There are 3 ways to get from Manaus to Santa Cruz by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Manaus (MAO) to Viru Viru International Airport (VVI)plane MAO - VVI
9h 39m$291–713Bus
cheapest- Take the bus from Terminal Rodoviário de Manaus to Estação Rodoviária de Humaitábus
- Take the bus from Estação Rodoviária de Humaitá to Rodoviária de Porto Velhobus
- Take the bus from Porto Velho to Cuscobus
- Take the bus from Cusco to Terminal de Buses La Pazbus
- Take the bus from La Paz to Santa Cruzbus
3d 14h$237–756Drive 8,516.7 km
- Drive from Manaus to Santa Cruz de la Sierracar 8,516.7 km
5d 8h$859–1,240
Manaus (MAO) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Manaus to Santa Cruz is to fly which costs $290 - $750 and takes 9h 39m.
The fastest way to get from Manaus to Santa Cruz is to fly which takes 9h 39m and costs $290 - $750.
No, there is no direct bus from Manaus to Santa Cruz. However, there are services departing from Terminal Rodoviário de Manaus and arriving at Santa Cruz via Estação Rodoviária de Humaitá, Porto Velho, Cusco and La Paz. The journey, including transfers, takes approximately 3 days 14h.
The distance between Manaus and Santa Cruz is 1691 km. The road distance is 8516.7 km.
The best way to get from Manaus to Santa Cruz without a car is to bus which takes 3 days 14h and costs $230 - $800.
It takes approximately 9h 39m to get from Manaus to Santa Cruz, including transfers.
Manaus to Santa Cruz bus services, operated by Eucatur, depart from Terminal Rodoviário de Manaus station.
The best way to get from Manaus to Santa Cruz is to fly which takes 9h 39m and costs $290 - $750. Alternatively, you can bus, which costs $230 - $800 and takes 3 days 14h.
Manaus to Santa Cruz bus services, operated by Eucatur, arrive at Estação Rodoviária de Humaitá station.
Yes, the driving distance between Manaus to Santa Cruz is 8517 km. It takes approximately 5 days 8h to drive from Manaus to Santa Cruz.
What companies run services between Manaus, Brazil and Santa Cruz, Bolivia?
Gol Transportes Aéreos, LATAM Chile, and Boliviana de Aviación fly from Manaus (MAO) to Viru Viru International Airport (VVI) 3 times a day. Alternatively, you can take a bus from Terminal Rodoviário de Manaus to Santa Cruz de la Sierra via Estação Rodoviária de Humaitá, Porto Velho, Cusco, La Paz, and Santa Cruz in around 3d 14h.
- Website
- voegol.com.br
Flights from Manaus to Viru Viru International Airport via Sao Paulo
- Ave. Duration
- 9h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,100
- Website
- boa.bo
Flights from Manaus to Viru Viru International Airport via Sao Paulo
- Ave. Duration
- 8h 50m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $350–1,100
- Phone
- 800 045 5050
- Website
- eucatur.com.br
Bus from Terminal Rodoviário de Manaus to Estação Rodoviária de Humaitá
- Ave. Duration
- 17h 56m
- Frequency
- 3 times a week
- Estimated price
- $55–85
- Schedules at
- eucatur.com.br
- Book at
- eucatur.com.br
Bus from Estação Rodoviária de Humaitá to Rodoviária de Porto Velho
- Ave. Duration
- 3h 10m
- Frequency
- 3 times a day
- Estimated price
- $15–24
- Schedules at
- eucatur.com.br
- Book at
- eucatur.com.br
- Phone
- 0800 880 2006
- [email protected]
- Website
- amatur.com.br
Bus from Estação Rodoviária de Humaitá to Rodoviária de Porto Velho
- Ave. Duration
- 3h 10m
- Frequency
- Twice daily
- Estimated price
- $20–30
- Schedules at
- amatur.com.br
- Book at
- amaturturismo.buson.com.br
- Phone
- +55 15 3292-1529
- Website
- eucatur.com.br
Bus from Estação Rodoviária de Humaitá to Rodoviária de Porto Velho
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $9–35
- Schedules at
- clickbus.com.br
- Phone
- +55 (68) 3221-1660
- Website
- transacreana.com.br
Bus from Porto Velho to Cusco
- Ave. Duration
- 30h 14m
- Frequency
- Once a week
- Estimated price
- $140–220
- Schedules at
- transacreana.com.br
- Book at
- transacreana.com.br
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from Cusco to Terminal de Buses La Paz
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $20–350
- Book at
- https://www.ticketsbolivia.com/company/nc_internacional.php
- Phone
- +591-72233555
- [email protected]
- Website
- transcopacabanasa.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $18–24
- Schedules at
- transcopacabanasa.com
- Phone
- +591 7297 1111
- Website
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- facebook.com
- Phone
- +591 69414917
- Website
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–19
- Schedules at
- facebook.com
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $16–19
- Phone
- +591 69416892
- [email protected]
- Website
- facebook.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- facebook.com
- Phone
- +59176400493
- Website
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $18–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
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