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How to get fromManaus to Santa Cruzby plane, bus, or car

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There are 3 ways to get from Manaus to Santa Cruz by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Manaus (MAO) to Viru Viru International Airport (VVI)plane plane MAO - VVI
    9h 39m
    $291–713
  2. Bus

    cheapest
    1. Take the bus from Terminal Rodoviário de Manaus to Estação Rodoviária de Humaitábus bus
    2. Take the bus from Estação Rodoviária de Humaitá to Rodoviária de Porto Velhobus bus
    3. Take the bus from Porto Velho to Cuscobus bus
    4. Take the bus from Cusco to Terminal de Buses La Pazbus bus
    5. Take the bus from La Paz to Santa Cruzbus bus
    3d 14h
    $237–756
  3. Drive 8,516.7 km

    1. Drive from Manaus to Santa Cruz de la Sierracar car 8,516.7 km
    5d 8h
    $859–1,240

Manaus (MAO) to Viru Viru International Airport (VVI) flights

Calendar18Weekly Planes
Duration9h 11mAverage Duration
Ticket$227Cheapest Price
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Questions & Answers

What companies run services between Manaus, Brazil and Santa Cruz, Bolivia?

Gol Transportes Aéreos, LATAM Chile, and Boliviana de Aviación fly from Manaus (MAO) to Viru Viru International Airport (VVI) 3 times a day. Alternatively, you can take a bus from Terminal Rodoviário de Manaus to Santa Cruz de la Sierra via Estação Rodoviária de Humaitá, Porto Velho, Cusco, La Paz, and Santa Cruz in around 3d 14h.

Airlines
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