There are 3 ways to get from Manaus to Santiago de Cuba by plane, shuttle, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Antonio Maceo International Airport
best- Fly from Manaus (MAO) to Antonio Maceo International Airport (SCU)plane MAO - SCU
12h 25m$263–1,015Fly to Frank País International Airport, shuttle
- Fly from Manaus (MAO) to Frank País International Airport (HOG)plane MAO - HOG
- Take a shuttle bus from Hotel Pernik Holguin to Melia Santiago de Cuba
34h 28m$313–1,200Fly to Ignacio Agramonte International Airport, bus
- Fly from Manaus (MAO) to Ignacio Agramonte International Airport (CMW)plane MAO - CMW
- Take the bus from Camagüey to Santiago de Cubabus
34h 37m$284–1,019
Manaus (MAO) to Antonio Maceo International Airport (SCU) flights
Questions & Answers
The cheapest way to get from Manaus to Santiago de Cuba is to fly which costs $260 - $1,100 and takes 12h 25m.
The fastest way to get from Manaus to Santiago de Cuba is to fly which takes 12h 25m and costs $260 - $1,100.
The distance between Manaus and Santiago de Cuba is 3101 km.
It takes approximately 12h 25m to get from Manaus to Santiago de Cuba, including transfers.
What companies run services between Manaus, Brazil and Santiago de Cuba?
Copa Airlines, Euroairlines, and InterCaribbean Airways fly from Manaus (MAO) to Antonio Maceo International Airport (SCU) twice a week.
- Website
- aa.com
Flights from Manaus to Frank País International Airport via Fortaleza, Miami
- Ave. Duration
- 30h 10m
- When
- Thursday
- Estimated price
- $600–1,800
Flights from Manaus to Frank País International Airport via Bogota, Miami
- Ave. Duration
- 33h 50m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $450–1,500
Flights from Manaus to Frank País International Airport via Panama City, Miami
- Ave. Duration
- 34h 25m
- When
- Every day
- Estimated price
- $290–1,100
Flights from Manaus to Frank País International Airport via Brasilia, Miami
- Ave. Duration
- 34h 35m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $600–1,700
Flights from Manaus to Ignacio Agramonte International Airport via Fortaleza, Miami
- Ave. Duration
- 29h 50m
- When
- Thursday
- Estimated price
- $550–1,700
Flights from Manaus to Ignacio Agramonte International Airport via Bogota, Miami
- Ave. Duration
- 33h 30m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- $420–1,400
Flights from Manaus to Ignacio Agramonte International Airport via Panama City, Miami
- Ave. Duration
- 34h 5m
- When
- Every day
- Estimated price
- $270–1,000
Flights from Manaus to Ignacio Agramonte International Airport via Brasilia, Miami
- Ave. Duration
- 34h 15m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $600–1,600
Flights from Manaus to Antonio Maceo International Airport via Panama City, Havana
- Ave. Duration
- 11h 25m
- When
- Wednesday
- Estimated price
- $320–1,200
Flights from Manaus to Frank País International Airport via Panama City, Havana
- Ave. Duration
- 33h 30m
- When
- Saturday
- Estimated price
- $270–1,100
Flights from Manaus to Ignacio Agramonte International Airport via Bogota, Cancun
- Ave. Duration
- 28h 35m
- When
- Tuesday
- Estimated price
- $430–1,400
Flights from Manaus to Ignacio Agramonte International Airport via Panama City, Cancun
- Ave. Duration
- 29h 10m
- When
- Tuesday
- Estimated price
- $270–1,100
- Website
- vivaaerobus.com
Flights from Manaus to Ignacio Agramonte International Airport via Bogota, Cancun
- Ave. Duration
- 28h 35m
- When
- Tuesday
- Estimated price
- $430–1,400
Flights from Manaus to Ignacio Agramonte International Airport via Panama City, Cancun
- Ave. Duration
- 29h 10m
- When
- Tuesday
- Estimated price
- $270–1,100
- Website
- intercaribbean.com
Flights from Manaus to Antonio Maceo International Airport via Panama City, Kingston
- Ave. Duration
- 16h 10m
- When
- Wednesday
- Estimated price
- $250–1,000
- Phone
- +(537) 206 9590
- [email protected]
- Website
- ecured.cu
Shuttle from Hotel Pernik Holguin to Melia Santiago de Cuba
- Ave. Duration
- 1h 9m
- Frequency
- Twice daily
- Estimated price
- $28–80
- Schedules at
- viajescubanacan.cu
- Phone
- +53 7873 7373
- [email protected]
- Website
- Ómnibus Nacionales
Bus from Camagüey to Santiago de Cuba
- Ave. Duration
- 4h
- Frequency
- 4 times a week
- Estimated price
- $2–5
- Schedules at
- Ómnibus Nacionales
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