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How to get fromManchester to Buffaloby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Manchester to Buffalo by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Manchester Airport to Buffalo Niagara International Airport

    best
    1. Fly from Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF)plane plane MHT - BUF
    6h 20m
    $146–879

  2. Drive  427.2 mi

    cheapest
    1. Drive from Manchester to Buffalocar car 427.2 mi
    8h 42m
    $78–113

  3. Bus (Greyhound)

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus Greyhound US0260
    2. Take the bus from Boston to Buffalobus bus Greyhound US0171
    12h 30m
    $84–134

  4. Bus, train

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus Greyhound US0260
    2. Take the train from Boston to Buffalo Depew Stationtrain train Lake Shore Limited
    15h 25m
    $271–574

  5. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    5h 58m
    $100–594

  6. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 29m
    $149–757

  7. Bus via Ithaca

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    14h 59m
    $88–139

Manchester to Buffalo by bus (Greyhound)

Calendar7Weekly Buses
Duration12h 30mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Manchester to Buffalo.ExpandLaunch map view
  • Distance: 383.9 mi
  • Duration: 6h 20m

What companies run services between Manchester, NH, USA and Buffalo, NY, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Manchester Airport (MHT) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Manchester(Veterans Memorial Park) to Buffalo via Boston in around 12h 30m.

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