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How to get fromManchester to Great Smoky Mountainsby plane, car, bus, or train

Find Transport to Great Smoky Mountains

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There are 9 ways to get from Manchester to Great Smoky Mountains by plane, car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Manchester Airport to Mcghee Tyson Airport, drive

    best
    1. Fly from Manchester Airport (MHT) to Mcghee Tyson Airport (TYS)plane plane MHT - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 21m
    $201–1,017

  2. Bus to Boston Logan Airport, fly to Asheville Regional Airport, drive

    cheapest
    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane plane BOS - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 39m
    $103–460

  3. Bus, train, drive

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    4. Drive from Knoxville, TN to Great Smoky Mountainscar car
    21h 35m
    $168–897

  4. Bus, train, drive via Lynchburg

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the train from Boston to Lynchburgtrain train
    3. Take the train from Lynchburg to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    24h 34m
    $266–571

  5. Drive 957.7 mi

    1. Drive from Manchester to Great Smoky Mountainscar car 957.7 mi
    17h 46m
    $175–253

  6. Fly Manchester Airport to Asheville Regional Airport, drive

    1. Fly from Manchester Airport (MHT) to Asheville Regional Airport (AVL)plane plane MHT - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 52m
    $110–523

  7. Bus to Boston Logan Airport, fly to Mcghee Tyson Airport, drive

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS)plane plane BOS - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    7h 33m
    $179–884

  8. Bus, drive

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the bus from Boston to New Yorkbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    4. Drive from Knoxville to Great Smoky Mountainscar car
    22h 26m
    $164–289

  9. Bus, drive via Farragut

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    4. Drive from Knoxville, TN to Great Smoky Mountainscar car
    22h 29m
    $145–199

Manchester Airport (MHT) to Mcghee Tyson Airport (TYS) flights

Calendar85Weekly Planes
Duration5h 20mAverage Duration
Ticket$197Cheapest Price
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Questions & Answers

Map of how to get from Manchester to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 894.7 mi
  • Duration: 7h 21m

What companies run services between Manchester, NH, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Manchester to Great Smoky Mountains. However, you can take the bus to Boston Manchester Airport, walk to Manchester Airport (MHT) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Manchester(Veterans Memorial Park) to Great Smoky Mountains via Boston, Boston, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, NY, and Knoxville, TN in around 21h 35m.

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