There are 8 ways to get from Manchester to Greenville by plane, bus (Greyhound, Flixbus), bus, train, car, taxi, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Manchester Airport to Greenville–Spartanburg International Airport
best- Fly from Manchester Airport (MHT) to Greenville–Spartanburg International Airport (GSP)plane MHT - GSP
5h 28m$476–946Drive 934.3 mi
cheapest- Drive from Manchester to Greenvillecar 934.3 mi
17h 32m$171–247Bus
- Take the bus from Manchester(Veterans Memorial Park) to Bostonbus
- Take the bus from Boston to NYC Downtownbus
- Take the bus from New York, NY to Gastonia, NC - Chester St.bus Nyc
- Take the bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenvillebus
20h 18m$183–360Bus, train
- Take the bus from Manchester(Veterans Memorial Park) to Bostonbus
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus
23h 44m$294–1,318Fly Manchester Airport to Asheville Regional Airport, taxi
- Fly from Manchester Airport (MHT) to Asheville Regional Airport (AVL)plane MHT - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
6h 48m$236–671Bus to Boston Logan Airport, fly to Asheville Regional Airport, taxi
- Take the bus from Manchester(Veterans Memorial Park) to Bostonbus
- Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane BOS - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
6h 35m$229–608Bus, train to Theodore Francis Green State Airport, fly to Greenville–Spartanburg International Airport
- Take the bus from Manchester(Veterans Memorial Park) to Bostonbus
- Take the train from South Station to TF Green Airporttrain
- Fly from Theodore Francis Green State Airport (PVD) to Greenville–Spartanburg International Airport (GSP)plane PVD - GSP
7h 42m$312–977Bus via Atlanta
- Take the bus from Manchester(Veterans Memorial Park) to Bostonbus
- Take the bus from Boston to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Atlanta Bus Stationbus
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus
32h 4m$231–513
Manchester Airport (MHT) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Manchester to Greenville is to drive which costs $170 - $250 and takes 17h 32m.
The fastest way to get from Manchester to Greenville is to fly which takes 5h 28m and costs $470 - $950.
No, there is no direct bus from Manchester to Greenville. However, there are services departing from Manchester(Veterans Memorial Park) and arriving at Taqueria Guadalajara - Greenville via Boston, New York, NY and Los Arcos Restaurant - Gastonia. The journey, including transfers, takes approximately 20h 18m.
The distance between Manchester and Greenville is 824 miles. The road distance is 939.7 miles.
The best way to get from Manchester to Greenville without a car is to bus which takes 20h 18m and costs $180 - $360.
It takes approximately 5h 28m to get from Manchester to Greenville, including transfers.
Manchester to Greenville bus services, operated by Greyhound USA, depart from Manchester(Veterans Memorial Park) station.
The best way to get from Manchester to Greenville is to fly which takes 5h 28m and costs $470 - $950. Alternatively, you can bus, which costs $180 - $360 and takes 20h 18m.
Manchester to Greenville bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Manchester to Greenville is 940 miles. It takes approximately 17h 32m to drive from Manchester to Greenville.
What companies run services between Manchester, NH, USA and Greenville, SC, USA?
Southwest Airlines, United Airlines, and American Airlines fly from Manchester Airport (MHT) to Greenville–Spartanburg International Airport (GSP) every 3 hours. Alternatively, you can take a bus from Manchester(Veterans Memorial Park) to Greenville via Boston, NYC Downtown, New York, NY, Gastonia, NC - Chester St., Los Arcos Restaurant - Gastonia, and Taqueria Guadalajara - Greenville in around 20h 18m.
- Website
- aa.com
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $140–750
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $140–750
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Manchester Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $100–550
Flights from Manchester Airport to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $140–650
Flights from Manchester Airport to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $95–500
Flights from Manchester Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 7h 9m
- When
- Sunday
- Estimated price
- $95–500
Flights from Boston Logan Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $80–430
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $100–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $100–600
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 4h 55m
- When
- Saturday and Tuesday
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 43m
- When
- Tuesday to Friday
- Estimated price
- $140–750
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $190–900
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 6m
- When
- Monday to Saturday
- Estimated price
- $100–600
- Website
- delta.com
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 40m
- When
- Saturday and Sunday
- Estimated price
- $80–420
Flights from Boston Logan Airport to Asheville Regional Airport via New York La Guardia
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $80–420
Flights from Boston Logan Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $100–490
- Website
- united.com
Flights from Manchester Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $140–750
Flights from Boston Logan Airport to Asheville Regional Airport via Newark
- Ave. Duration
- 5h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–420
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $100–600
- Website
- allegiantair.com
Flights from Boston Logan Airport to Asheville Regional Airport
- Ave. Duration
- 2h 21m
- When
- Monday and Friday
- Estimated price
- $80–420
- Website
- flybreeze.com
Flights from Theodore Francis Green State Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 22m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $260–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $70–150
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Charlotte Amtrak Station
- Ave. Duration
- 12h 30m
- Frequency
- Twice daily
- Estimated price
- $180–390
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
Train from South Station to TF Green Airport
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Manchester(Veterans Memorial Park) to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Manchester(Veterans Memorial Park) to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Manchester(Veterans Memorial Park) to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Manchester(Veterans Memorial Park) to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Manchester(Veterans Memorial Park) to Boston
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Boston to Port Authority Bus Terminal
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Atlanta Bus Station
- Ave. Duration
- 18h 35m
- Frequency
- 4 times a day
- Estimated price
- $130–260
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to NYC Downtown
- Ave. Duration
- 5h
- Frequency
- Every 4 hours
- Estimated price
- $30–55
- Schedules at
- Flixbus USA
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York, NY to Gastonia, NC - Chester St.
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $90–130
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $90–130
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Los Arcos Restaurant - Gastonia to Taqueria Guadalajara - Greenville
- Ave. Duration
- 1h 57m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $45–150
- Ave. Duration
- 1h
- Estimated price
- $140–170
Asheville Taxi
- Phone
- +1 828-333-1976
- Website
- avltaxi.com
Asheville Taxi
- Phone
- +1 828-333-1976
- Website
- avltaxi.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Manchester to Greenville bus tickets online with Omio.
There are 225+ hotels available in Greenville.













