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How to get fromManchester to Mayo Clinicby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 7 ways to get from Manchester to Mayo Clinic by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Manchester Airport to Rochester

    best
    1. Fly from Manchester Airport (MHT) to Rochester (RST)plane plane MHT - RST
    9h 48m
    $122–592

  2. Bus to Boston Logan Airport, fly to Rochester

    cheapest
    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (RST)plane plane BOS - RST
    9h 39m
    $111–549

  3. Bus

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    5. Take the bus from Milwaukee to Rochesterbus bus
    33h 30m
    $262–442

  4. Bus, train via Madison

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    34h 53m
    $404–846

  5. Drive 1,300.2 mi

    1. Drive from Manchester to Mayo Cliniccar car 1,300.2 mi
    23h 18m
    $238–343

  6. Bus to Boston Logan Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Minneapolis–Saint Paul International Airport (MSP)plane plane BOS - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    9h 16m
    $402–1,021

  7. Bus, train

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    35h 51m
    $487–1,026

Manchester to Mayo Clinic by bus and foot

Calendar7Weekly Services
Duration33h 30mAverage Duration
Ticket$262Cheapest Price
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Questions & Answers

Map of how to get from Manchester to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,070.5 mi
  • Duration: 9h 48m

What companies run services between Manchester, NH, USA and Mayo Clinic, MN, USA?

American Airlines and United Airlines fly from Manchester Airport (MHT) to Rochester (RST) 5 times a day. Alternatively, you can take a bus from Manchester(Veterans Memorial Park) to Mayo Clinic via Boston, New York Midtown, Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 33h 30m.

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