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How to get fromManchester to Winston-Salemby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Manchester to Winston-Salem by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Manchester Airport (MHT) to Piedmont Triad International Airport (GSO)plane plane MHT - GSO
    6h 21m
    $150–774

  2. Bus via New York

    cheapest
    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the bus from Boston to NYC Downtownbus bus
    3. Take the bus from New York, NY to Winston-Salem, NCbus bus Nyc
    18h 25m
    $119–186

  3. Bus, train

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the train from Boston to Lynchburgtrain train
    3. Take the train from Lynchburg to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    19h 46m
    $248–519

  4. Drive 765.4 mi

    1. Drive from Manchester to Winston-Salemcar car 765.4 mi
    14h 49m
    $140–202

  5. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Manchester Airport (MHT) to Charlotte Douglas International Airport (CLT)plane plane MHT - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    6h 54m
    $142–747

  6. Fly to Raleigh-Durham International Airport, bus

    1. Fly from Manchester Airport (MHT) to Raleigh-Durham International Airport (RDU)plane plane MHT - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    7h 25m
    $148–630

  7. Bus (Greyhound)

    1. Take the bus from Manchester(Veterans Memorial Park) to Bostonbus bus
    2. Take the bus from Boston to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Winston Salem(Trans Center)bus bus
    22h 53m
    $134–271

Manchester to Winston-Salem by bus and train

Calendar5Weekly Services
Duration19h 46mAverage Duration
Ticket$248Cheapest Price
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Questions & Answers

Map of how to get from Manchester to Winston-Salem.ExpandLaunch map view
  • Distance: 681.5 mi
  • Duration: 6h 21m

What companies run services between Manchester, NH, USA and Winston-Salem, NC, USA?

United Airlines and American Airlines fly from Manchester Airport (MHT) to Piedmont Triad International Airport (GSO) every 4 hours. Alternatively, you can take a bus from Manchester(Veterans Memorial Park) to Winston-Salem, NC via Boston, NYC Downtown, and New York, NY in around 18h 25m.

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