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How to get fromManchester to Knoxvilleby plane, car, or shuttle

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There are 6 ways to get from Manchester to Knoxville by plane, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Manchester Airport (MAN) to Mcghee Tyson Airport (TYS)plane plane MAN - TYS
    14h 2m
    $659–2,478

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Manchester Airport (MAN) to Asheville Regional Airport (AVL)plane plane MAN - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    16h 48m
    $266–993

  3. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Manchester Airport (MAN) to Chattanooga Metropolitan Airport (CHA)plane plane MAN - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    15h 40m
    $272–986

  4. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Manchester Airport (MAN) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MAN - ATL
    2. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    15h 38m
    $329–1,168

  5. Fly to Greenville–Spartanburg International Airport, drive

    1. Fly from Manchester Airport (MAN) to Greenville–Spartanburg International Airport (GSP)plane plane MAN - GSP
    2. Drive from Greenville–Spartanburg International Airport (GSP) to Knoxvillecar car
    17h 43m
    $424–1,558

  6. Fly to Tri-Cities Regional Tn/Va Airport, shuttle, drive

    1. Fly from Manchester Airport (MAN) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane MAN - TRI
    2. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    3. Drive from Hot Springs to Knoxvillecar car
    19h 52m
    $461–1,182

Manchester Airport (MAN) to Mcghee Tyson Airport (TYS) flights

Calendar13Weekly Planes
Duration11h 56mAverage Duration
Ticket$642Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Manchester to Knoxville.ExpandLaunch map view
  • Distance: 3,986.9 mi
  • Duration: 14h 2m

What companies run services between Manchester, England and Knoxville, TN, USA?

Virgin Atlantic and Delta fly from Manchester Airport (MAN) to Mcghee Tyson Airport (TYS) twice daily.

Airlines
Bus operators

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