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How to get fromManchester to Knoxvilleby plane, car, or shuttle

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There are 5 ways to get from Manchester to Knoxville by plane, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Manchester Airport (MAN) to Mcghee Tyson Airport (TYS)plane plane MAN - TYS
    14h 10m
    $609–2,278

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Manchester Airport (MAN) to Asheville Regional Airport (AVL)plane plane MAN - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    16h 2m
    $266–993

  3. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Manchester Airport (MAN) to Chattanooga Metropolitan Airport (CHA)plane plane MAN - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    15h 39m
    $272–1,036

  4. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Manchester Airport (MAN) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane MAN - ATL
    2. Drive from Atlanta-Airport-ATL to Knoxvillecar car
    15h 22m
    $459–1,368

  5. Fly to Tri-Cities Regional Tn/Va Airport, shuttle, drive

    1. Fly from Manchester Airport (MAN) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane MAN - TRI
    2. Take a shuttle bus from Black Bear Resort to Hot Springsshuttle bus
    3. Drive from Hot Springs to Knoxvillecar car
    19h 48m
    $461–1,182

Manchester Airport (MAN) to Mcghee Tyson Airport (TYS) flights

Calendar23Weekly Planes
Duration12h 40mAverage Duration
Ticket$566Cheapest Price
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Comparing Your Travel Options

Map of how to get from Manchester to Knoxville.ExpandLaunch map view
  • Distance: 3,987.2 mi
  • Duration: 14h 10m

What companies run services between Manchester, England and Knoxville, TN, USA?

Virgin Atlantic, Delta, and Southwest Airlines fly from Manchester Airport (MAN) to Mcghee Tyson Airport (TYS) 3 times a day.

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