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How to get fromManhattan to Chicagoby plane, car, train, bus (Greyhound, Flixbus), or bus

Find Transport to Chicago

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There are 5 ways to get from Manhattan to Chicago by plane, car, train, bus (Greyhound, Flixbus), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Manhattan Regional Airport (MHK) to Chicago O'Hare International Airport (ORD)plane plane MHK - ORD
    2h 55m
    $83–322
  2. Drive, train (Amtrak)

    1. Drive from Manhattan to Topeka Stationcar car
    2. Take the train from Topeka Station to Chicago Union Stationtrain train Southwest Chief
    11h 15m
    $170–345
  3. Bus

    1. Take the bus from Manhattan KS to St Louis Bus Stationbus bus Greyhound US0180s
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    15h 10m
    $111–205
  4. Drive 608.8 mi

    1. Drive from Manhattan to Chicagocar car 608.8 mi
    11h 4m
    $112–161
  5. Bus, train

    1. Take the bus from Manhattan KS to Kansas City Bus Stationbus bus Greyhound US0180s
    2. Take the train from Kansas City to Chicago Union Stationtrain train Southwest Chief / ...
    12h 37m
    $163–334

Manhattan to Chicago by bus

Calendar7Weekly Buses
Duration15h 10mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

What companies run services between Manhattan, KS, USA and Chicago, IL, USA?

American Airlines flies from Manhattan Regional Airport (MHK) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a bus from Manhattan KS to Chicago Bus Station via St Louis Bus Station in around 15h 10m.

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