There are 5 ways to get from Manhattan to Key West by plane, bus (Greyhound, Flixbus), car, train, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Manhattan Regional Airport (MHK) to Key West International Airport (EYW)plane MHK - EYW
7h 13m$152–510Bus
- Take the bus from Manhattan KS to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
41h 36m$270–543Drive, train, bus
- Drive from Manhattan to Topeka Stationcar
- Take the train from Topeka Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
2d 18h$845–1,795Drive 1,663.5 mi
- Drive from Manhattan to Key Westcar 1,663.5 mi
30h 42m$304–439Bus, ferry
- Take the bus from Manhattan KS to Kansas City Bus Stationbus
- Take the bus from Kansas City to Texarkanabus
- Take the bus from Texarkana to Houston Bus Stationbus
- Take the bus from Houston - Harrisburg Blvd to Fort Myersbus
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry
2d 1h$539–725
Manhattan to Key West by bus and foot
Questions & Answers
The cheapest way to get from Manhattan to Key West is to fly which costs $150 - $550 and takes 7h 13m.
The fastest way to get from Manhattan to Key West is to fly which takes 7h 13m and costs $150 - $550.
No, there is no direct bus from Manhattan to Key West. However, there are services departing from Manhattan KS and arriving at N Roosevelt & 3rd Street via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 41h 36m.
The distance between Manhattan and Key West is 1348 miles. The road distance is 1673.2 miles.
The best way to get from Manhattan to Key West without a car is to bus which takes 41h 36m and costs $270 - $550.
It takes approximately 7h 13m to get from Manhattan to Key West, including transfers.
Manhattan to Key West bus services, operated by Greyhound USA, depart from Manhattan KS station.
The best way to get from Manhattan to Key West is to fly which takes 7h 13m and costs $150 - $550. Alternatively, you can bus, which costs $270 - $550 and takes 41h 36m.
Manhattan to Key West bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Key West is 1h ahead of Manhattan. It is currently 4:02 PM in Manhattan and 5:02 PM in Key West.
What companies run services between Manhattan, KS, USA and Key West, FL, USA?
American Airlines and United Airlines fly from Manhattan Regional Airport (MHK) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a bus from Manhattan KS to N Roosevelt & 3rd Street via St Louis Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 41h 36m.
- Website
- aa.com
Flights from Manhattan Regional Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $120–500
Flights from Manhattan Regional Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 52m
- When
- Every day
- Estimated price
- $110–460
Flights from Manhattan Regional Airport to Key West International Airport via Dallas/Ft.Worth, Miami
- Ave. Duration
- 11h 31m
- When
- Every day
- Estimated price
- $110–490
- Website
- united.com
Flights from Manhattan Regional Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $120–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Topeka Station to Chicago Union Station
- Ave. Duration
- 10h 17m
- Frequency
- Once daily
- Estimated price
- $160–330
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Hollywood Amtrak Station
- Ave. Duration
- 46h 6m
- Frequency
- Once daily
- Estimated price
- $650–1,400
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Manhattan KS to St Louis Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $85–170
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $100–210
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Manhattan KS to Kansas City Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $24–50
- Website
- https://www.greyhound.com/
Bus from Texarkana to Houston Bus Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
- Website
- flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 30m
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- 5 times a week
- Estimated price
- $85–150
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $110–190
- Schedules at
- flixbus.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Schedules at
- greyhound.com
Bus from Texarkana to Houston Bus Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Schedules at
- greyhound.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Texarkana
- Ave. Duration
- 8h 55m
- Frequency
- 4 times a day
- Estimated price
- $110–160
- Book at
- https://www.jeffersonlines.com
- Adult
- $110–160
- Phone
- +1 800-923-1799
- [email protected]
- Website
- omnibusexpress.com
Bus from Houston - Harrisburg Blvd to Fort Myers
- Ave. Duration
- 20h 38m
- Frequency
- Once daily
- Estimated price
- $170–220
- Schedules at
- omnibusexpress.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Manhattan to Key West is 1673 miles. It takes approximately 30h 42m to drive from Manhattan to Key West.
There are 947+ hotels available in Key West.


















