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How to get fromManhattan to Louisvilleby plane, bus (Greyhound), car, train, or bus

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There are 6 ways to get from Manhattan to Louisville by plane, bus (Greyhound), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Manhattan Regional Airport to Louisville International Airport

    best
    1. Fly from Manhattan Regional Airport (MHK) to Louisville International Airport (SDF)plane plane MHK - SDF
    6h 54m
    $142–640

  2. Drive 624.4 mi

    cheapest
    1. Drive from Manhattan to Louisvillecar car 624.4 mi
    10h 22m
    $114–165

  3. Bus

    1. Take the bus from Manhattan KS to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    3. Take the bus from Evansville, IN to Louisville, KYbus bus
    15h 45m
    $120–218

  4. Drive, train, bus (Amtrak)

    1. Drive from Manhattan to Topeka Stationcar car
    2. Take the train from Topeka Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    20h 34m
    $252–520

  5. Fly Manhattan Regional Airport to Blue Grass Airport, drive

    1. Fly from Manhattan Regional Airport (MHK) to Blue Grass Airport (LEX)plane plane MHK - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 58m
    $214–956

  6. Bus to Salina Municipal Airport, fly to Louisville International Airport

    1. Take the bus from Manhattan KS to Salinabus bus
    2. Fly from Salina Municipal Airport (SLN) to Louisville International Airport (SDF)plane plane SLN - SDF
    9h 57m
    $143–638

Manhattan to Louisville by bus

Calendar7Weekly Buses
Duration15h 45mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Louisville.ExpandLaunch map view
  • Distance: 606.2 mi
  • Duration: 6h 54m

What companies run services between Manhattan, KS, USA and Louisville, KY, USA?

American Airlines flies from Manhattan Regional Airport (MHK) to Louisville International Airport (SDF) twice daily. Alternatively, you can take a bus from Manhattan KS to Louisville, KY via St Louis Bus Station and Evansville, IN in around 15h 45m.

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