There are 4 ways to get from Manhattan to Mayo Clinic by bus, shuttle, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, shuttle
best- Take the bus from Manhattan KS to Kansas City Bus Stationbus
- Take the bus from Kansas City to Owatonnabus
- Take a shuttle bus from Owatonna, MN to Rochester
13h 30m$118–213Drive 509.7 mi
cheapest- Drive from Manhattan to Mayo Cliniccar 509.7 mi
8h 43m$93–135Fly
- Fly from Manhattan Regional Airport (MHK) to Rochester (RST)plane MHK - RST
8h 7m$112–477Bus
- Take the bus from Manhattan KS to Kansas City Bus Stationbus
- Take the bus from Kansas City Bus Station to Saint Paul Union Depotbus
- Take the bus from St. Paul to Rochesterbus
15h 48m$151–233
Manhattan to Mayo Clinic by bus and foot
Questions & Answers
The cheapest way to get from Manhattan to Mayo Clinic is to drive which costs $90 - $140 and takes 8h 43m.
The fastest way to get from Manhattan to Mayo Clinic is to fly which takes 8h 7m and costs $110 - $480.
No, there is no direct bus from Manhattan to Mayo Clinic. However, there are services departing from Manhattan KS and arriving at Rochester via Kansas City Bus Station and St. Paul. The journey, including transfers, takes approximately 15h 48m.
The distance between Manhattan and Mayo Clinic is 575 miles. The road distance is 512.6 miles.
The best way to get from Manhattan to Mayo Clinic without a car is to bus and shuttle which takes 13h 30m and costs $110 - $220.
It takes approximately 13h 30m to get from Manhattan to Mayo Clinic, including transfers.
Manhattan to Mayo Clinic bus services, operated by Greyhound USA, depart from Manhattan KS station.
The best way to get from Manhattan to Mayo Clinic is to fly which takes 8h 7m and costs $110 - $480. Alternatively, you can bus, which costs $150 - $240 and takes 15h 48m.
Manhattan to Mayo Clinic bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
Yes, the driving distance between Manhattan to Mayo Clinic is 513 miles. It takes approximately 8h 43m to drive from Manhattan to Mayo Clinic.
What companies run services between Manhattan, KS, USA and Mayo Clinic, MN, USA?
American Airlines flies from Manhattan Regional Airport (MHK) to Rochester (RST) 4 times a day. Alternatively, you can take a bus from Manhattan KS to Mayo Clinic via Kansas City Bus Station, St. Paul, and Rochester in around 15h 48m.
- Website
- aa.com
Flights from Manhattan Regional Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 9h 13m
- When
- Every day
- Estimated price
- $80–400
Flights from Manhattan Regional Airport to Rochester via Dallas/Ft.Worth, Chicago O'Hare
- Ave. Duration
- 12h 35m
- When
- Every day
- Estimated price
- $130–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Manhattan KS to Kansas City Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Manhattan KS to Kansas City Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Greyhound
Bus from Kansas City Bus Station to Saint Paul Union Depot
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $65–130
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Owatonna
- Ave. Duration
- 7h 15m
- Frequency
- 3 times a day
- Estimated price
- $90–130
- Book at
- Jefferson Lines
- Adult
- $90–130
Bus from Kansas City Bus Station to Saint Paul Union Depot
- Ave. Duration
- 8h 25m
- Frequency
- Twice daily
- Estimated price
- $100–150
- Book at
- Jefferson Lines
- Adult
- $100–150
Bus from St. Paul to Rochester
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $28–40
- Book at
- Jefferson Lines
- Adult
- $28–40
- Phone
- +1 (888) 736-9190
- [email protected]
- Website
- landtoairexpress.com
Shuttle from Owatonna, MN to Rochester
- Ave. Duration
- 1h
- Frequency
- Twice daily
- Estimated price
- $5–40
- Schedules at
- landtoairexpress.com
- Adult
- $5–40
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