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How to get fromManhattan to Sioux Fallsby car, bus, plane, or bus (Greyhound)

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There are 5 ways to get from Manhattan to Sioux Falls by car, bus, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus

    best
    1. Drive from Manhattan to Topekacar car
    2. Take the bus from Topeka to Omahabus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    9h 56m
    $219–253

  2. Drive 331.7 mi

    cheapest
    1. Drive from Manhattan to Sioux Fallscar car 331.7 mi
    6h 10m
    $61–88

  3. Fly from Manhattan Regional Airport

    1. Fly from Manhattan Regional Airport (MHK) to Sioux Falls (FSD)plane plane MHK - FSD
    7h 18m
    $123–479

  4. Bus

    1. Take the bus from Manhattan KS to Kansas City Bus Stationbus bus Greyhound US0180s
    2. Take the bus from Kansas City to Sioux Fallsbus bus Jefferson Lines 705
    14h 28m
    $120–185

  5. Bus to Salina Municipal Airport, fly

    1. Take the bus from Manhattan KS to Salinabus bus
    2. Fly from Salina Municipal Airport (SLN) to Sioux Falls (FSD)plane plane SLN - FSD
    8h 1m
    $109–457

Manhattan Regional Airport (MHK) to Sioux Falls (FSD) flights

Calendar42Weekly Planes
Duration8h 6mAverage Duration
Ticket$93Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Sioux Falls.ExpandLaunch map view
  • Distance: 413 mi
  • Duration: 9h 56m

What companies run services between Manhattan, KS, USA and Sioux Falls, SD, USA?

American Airlines flies from Manhattan Regional Airport (MHK) to Sioux Falls (FSD) every 4 hours. Alternatively, you can take a bus from Manhattan KS to The Bus Stop via Kansas City Bus Station, Kansas City, Sioux Falls, and Maple/Career NE corner in around 14h 28m.

Airlines
Bus operators

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