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How to get fromManhattan to Cape Girardeauby plane, bus, bus (Greyhound), train, taxi, or car

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There are 12 ways to get from Manhattan to Cape Girardeau by plane, bus, bus (Greyhound), train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    7h 52m
    $191–854

  2. Fly Laguardia Airport to Cape Girardeau Municipal Airport

    cheapest
    1. Fly from Laguardia Airport (LGA) to Cape Girardeau Municipal Airport (CGI)plane plane LGA - CGI
    6h 52m
    $146–635

  3. Bus

    1. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    26h 9m
    $191–357

  4. Train, taxi

    1. Take the train from 125th Street - Harlem to Croton-Harmontrain train
    2. Take the train from Croton-Harmon Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Carbondaletrain train
    4. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    28h 18m
    $510–1,006

  5. Drive 988.2 mi

    1. Drive from Manhattan to Cape Girardeaucar car 988.2 mi
    17h 45m
    $181–261

  6. Fly Newark Liberty International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h
    $418–874

  7. Fly John F. Kennedy International Airport to Lambert–St. Louis International Airport, bus

    1. Fly from John F. Kennedy International Airport (JFK) to Lambert–St. Louis International Airport (STL)plane plane JFK - STL
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h 21m
    $162–665

  8. Fly Laguardia Airport to Memphis, bus

    1. Fly from Laguardia Airport (LGA) to Memphis (MEM)plane plane LGA - MEM
    2. Take the bus from Memphis Bus Station to Cape Girardeaubus bus
    10h
    $239–1,022

  9. Fly Laguardia Airport to Nashville, bus, taxi

    1. Fly from Laguardia Airport (LGA) to Nashville (BNA)plane plane LGA - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    10h 24m
    $245–744

  10. Fly Newark Liberty International Airport to Nashville, bus, taxi

    1. Fly from Newark Liberty International Airport (EWR) to Nashville (BNA)plane plane EWR - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    10h 22m
    $652–1,814

  11. Fly John F. Kennedy International Airport to Nashville, bus, taxi

    1. Fly from John F. Kennedy International Airport (JFK) to Nashville (BNA)plane plane JFK - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the taxi from Carbondale Intermodal Station to Cape Girardeautaxi taxi
    10h 30m
    $606–1,305

  12. Train, bus

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    29h 57m
    $428–891

Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL) flights

Calendar69Weekly Planes
Duration2h 43mAverage Duration
Ticket$161Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Cape Girardeau.ExpandLaunch map view
  • Distance: 1,022.9 mi
  • Duration: 7h 52m

What companies run services between Manhattan, NY, USA and Cape Girardeau, MO, USA?

You can take a bus from Port Authority Bus Terminal to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 26h 9m. Alternatively, Delta, Corporate Flight Management Inc, and American Airlines fly from Laguardia Airport (LGA) to Cape Girardeau Municipal Airport (CGI) twice daily.

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