There are 9 ways to get from Manhattan to Carlisle by train (Amtrak), bus, car, plane, train, taxi, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain Acela
5h 15m$103–192Drive 201.4 mi
cheapest- Drive from Manhattan to Carlislecar 201.4 mi
4h 9m$37–54Bus
- Take the bus from Manhattan, NY to Cambridge - Alewife Stationbus Manhattan-Cambridge
5h 23m$60–76Bus to Laguardia Airport, fly to Boston Logan Airport, train, taxi
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Boston Logan Airport (BOS)plane LGA - BOS
- Take the train from Anderson/Woburn to North Billericatrain
- Take the taxi from North Billerica to Carlisletaxi
4h 44m$80–391Bus via Boston
- Take the bus from Port Authority Bus Terminal to South Stationbus New York
6h 20m$56–94Train to John F. Kennedy International Airport, fly to Boston Logan Airport, train, taxi
- Take the train from Grand Central Terminal to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Boston Logan Airport (BOS)plane JFK - BOS
- Take the train from Anderson/Woburn to North Billericatrain
- Take the taxi from North Billerica to Carlisletaxi
4h 40m$246–1,062Train to Newark Liberty International Airport, fly to Boston Logan Airport, train, taxi
- Take the train from New York Penn Station to Newark Airport Railroad Stationtrain
- Fly from Newark Liberty International Airport (EWR) to Boston Logan Airport (BOS)plane EWR - BOS
- Take the train from Anderson/Woburn to North Billericatrain
- Take the taxi from North Billerica to Carlisletaxi
4h 47m$512–1,671Fly Laguardia Airport to Worcester Regional Airport, taxi
- Fly from Laguardia Airport (LGA) to Worcester Regional Airport (ORH)plane LGA - ORH
- Take the taxi from Worcester-Airport-ORH to Carlisletaxi
4h 1m$168–507Train to Long Island Mac Arthur Airport, fly to Boston Logan Airport
- Take the train from New York Penn Station to Central Isliptrain
- Fly from Long Island Mac Arthur Airport (ISP) to Boston Logan Airport (BOS)plane ISP - BOS
6h 29m$298–424
Laguardia Airport (LGA) to Boston Logan Airport (BOS) flights
Questions & Answers
The cheapest way to get from Manhattan to Carlisle is to drive which costs $35 - $55 and takes 4h 9m.
The fastest way to get from Manhattan to Carlisle is to fly and taxi which takes 4h 1m and costs $160 - $550.
No, there is no direct bus from Manhattan to Carlisle. However, there are services departing from Manhattan, NY and arriving at South Rd @ Great Rd via Alewife. The journey, including transfers, takes approximately 5h 23m.
No, there is no direct train from Manhattan station to Carlisle. However, there are services departing from Ny Moynihan Train Hall At Penn Station and arriving at North Billerica via Back Bay and North Station. The journey, including transfers, takes approximately 5h 15m.
The distance between Manhattan and Carlisle is 262 miles. The road distance is 202.5 miles.
The best way to get from Manhattan to Carlisle without a car is to train which takes 5h 15m and costs $100 - $200.
It takes approximately 5h 15m to get from Manhattan to Carlisle, including transfers.
Manhattan to Carlisle bus services, operated by Go Buses, depart from Manhattan, NY station.
Manhattan to Carlisle train services, operated by Amtrak Acela, depart from Ny Moynihan Train Hall At Penn Station.
The best way to get from Manhattan to Carlisle is to train which takes 5h 15m and costs $100 - $200. Alternatively, you can bus, which costs $55 - $80 and takes 5h 23m.
What companies run services between Manhattan, NY, USA and Carlisle, MA, USA?
Amtrak Acela operates a train from Ny Moynihan Train Hall At Penn Station to Boston every 4 hours. Tickets cost $50–750 and the journey takes 3h 36m. Amtrak also services this route every 3 hours. Alternatively, Go Buses operates a bus from Manhattan, NY to Cambridge - Alewife Station twice daily. Tickets cost $40–50 and the journey takes 4h 15m.
- Website
- delta.com
Flights from Laguardia Airport to Boston Logan Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $45–340
Flights from John F. Kennedy International Airport to Boston Logan Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $35–270
Flights from Newark Liberty International Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $40–280
Flights from Laguardia Airport to Worcester Regional Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $45–350
- Website
- united.com
Flights from Newark Liberty International Airport to Boston Logan Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $40–280
- Website
- aa.com
Flights from Laguardia Airport to Boston Logan Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $45–340
Flights from John F. Kennedy International Airport to Boston Logan Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $35–270
- Website
- jetblue.com
Flights from Laguardia Airport to Boston Logan Airport via Nantucket
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- $55–370
Flights from John F. Kennedy International Airport to Boston Logan Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $35–270
- Website
- capeair.com
Flights from Long Island Mac Arthur Airport to Boston Logan Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $250–350
- Website
- southwest.com
Flights from Long Island Mac Arthur Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $70–390
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Ny Moynihan Train Hall At Penn Station to Boston
- Ave. Duration
- 4h 14m
- Frequency
- Every 3 hours
- Estimated price
- $70–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Anderson/Woburn to North Billerica
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1–8
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $1–8
Train from Anderson/Woburn to North Billerica
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1–8
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $1–8
Train from Anderson/Woburn to North Billerica
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $1–8
- Website
- https://www.mbta.com
- Website
- https://www.mbta.com/guides/world-cup-guide
- Adult
- $1–8
- Phone
- +1-718-217-5477
- Website
- mta.info
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 20 min
- Frequency
- Every 15 minutes
- Estimated price
- $5–9
- Website
- https://www.mta.info/agency/long-island-rail-road
- Schedules at
- https://www.mta.info/agency/long-island-rail-road/timetables
- Off-Peak
- $5–8
- Peak
- $5–9
Train from New York Penn Station to Central Islip
- Ave. Duration
- 1h 14m
- Frequency
- Every 30 minutes
- Estimated price
- $12–28
- Website
- https://www.mta.info/agency/long-island-rail-road
- Schedules at
- https://www.mta.info/agency/long-island-rail-road/timetables
- Off-Peak
- $12–18
- Peak
- $20–28
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Train from New York Penn Station to Newark Airport Railroad Station
- Ave. Duration
- 24 min
- Frequency
- Every 20 minutes
- Estimated price
- $15–19
- Website
- https://www.njtransit.com
- Website
- https://njtworldcup.com/
- Adult Airport
- $15–19
- Phone
- 1 855-888-7160
- [email protected]
- Website
- gobuses.com
Bus from Manhattan, NY to Cambridge - Alewife Station
- Ave. Duration
- 4h 15m
- Frequency
- Twice daily
- Estimated price
- $40–50
- Website
- https://www.gobuses.com
- Phone
- 877-690-5116
- Website
- mta.info
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- https://www.mta.info/
- Schedules at
- https://www.mta.info/schedules
- Website
- https://www.mta.info/world-cup-2026-new-york-new-jersey
- Standard Fare
- $3–8
- Phone
- 1-800-343-9999
- Website
- peterpanbus.com
Bus from Port Authority Bus Terminal to South Station
- Ave. Duration
- 4h 35m
- Frequency
- Every 2 hours
- Estimated price
- $40–120
- Website
- https://peterpanbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Port Authority Bus Terminal to South Station
- Ave. Duration
- 5h 4m
- Frequency
- Hourly
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Ave. Duration
- 26 min
- Estimated price
- $22–150
Merrimack Taxi Co
- Phone
- +1 978-687-0911
Merrimack Taxi Co
- Phone
- +1 978-687-0911
Merrimack Taxi Co
- Phone
- +1 978-687-0911
Red Cab
- Phone
- +1 508-792-9999
- Website
- worcredcab.com
Worcester Green Cab
- Phone
- +1 508-459-1611
- Website
- worcestergreencab.com
Yellow Cab
- Phone
- +1 508-754-3211
- Website
- yellowcabworcester.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Manhattan to Carlisle bus services, operated by Go Buses, arrive at Cambridge - Alewife Station.
Manhattan to Carlisle train services, operated by Amtrak Acela, arrive at Boston station.
Yes, the driving distance between Manhattan to Carlisle is 203 miles. It takes approximately 4h 9m to drive from Manhattan to Carlisle.
There are 174+ hotels available in Carlisle.













