There are 8 ways to get from Manhattan to Destiny USA by bus (Greyhound, Flixbus), train, car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Port Authority Bus Terminal to Syracuse Bus Stationbus Greyhound US0205 / ...
4h 54m$40–160Train
- Take the train from New York Penn Station to Syracusetrain VIA Rail
5h 48m$75–230Drive 253 mi
- Drive from Manhattan to Destiny USAcar 253 mi
4h 37m$44–63Bus to Laguardia Airport, fly to Syracuse Hancock International Airport
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
4h 37m$59–399Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport
- Take the train from Grand Central Terminal to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
4h 43m$50–270Fly Laguardia Airport to Rochester, train
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 32m$102–599Train to Philadelphia International Airport, fly to Syracuse Hancock International Airport
- Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain
- Fly from Philadelphia International Airport (PHL) to Syracuse Hancock International Airport (SYR)plane PHL - SYR
6h 10m$99–1,152Fly John F. Kennedy International Airport to Ithaca Tompkins Regional Airport, bus
- Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)plane JFK - ITH
- Take the bus from Ithaca to Syracuse Bus Stationbus
6h 35m$59–283
Manhattan to Destiny USA by bus and foot
Comparing Your Travel Options
The cheapest way to get from Manhattan to Destiny USA is to drive which costs $40 - $65 and takes 4h 37m.
The fastest way to get from Manhattan to Destiny USA is to drive which takes 4h 37m and costs $40 - $65.
Yes, there is a direct bus departing from Port Authority Bus Terminal and arriving at Syracuse Bus Station station. Services depart every three hours, and operate every day. The journey takes approximately 4h 45m.
Yes, there is a direct train departing from New York Penn Station station and arriving at Syracuse. Services depart once daily, and operate every day. The journey takes approximately 5h 39m.
The distance between Manhattan and Destiny USA is 262 miles. The road distance is 254.4 miles.
The best way to get from Manhattan to Destiny USA without a car is to bus which takes 4h 54m and costs $40 - $160.
The bus from Port Authority Bus Terminal to Syracuse Bus Station takes 4h 45m including transfers and departs every three hours.
Manhattan to Destiny USA bus services, operated by Greyhound USA, depart from Port Authority Bus Terminal station.
Manhattan to Destiny USA train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Manhattan to Destiny USA is to bus which takes 4h 54m and costs $40 - $160. Alternatively, you can train, which costs $75 - $230 and takes 5h 48m.
What companies run services between Manhattan, NY, USA and Destiny USA, NY, USA?
Greyhound USA operates a bus from Port Authority Bus Terminal to Syracuse Bus Station every 4 hours. Tickets cost $45–70 and the journey takes 4h 45m. Two other operators also service this route. Alternatively, VIA Rail operates a train from New York Penn Station to Syracuse once daily. Tickets cost $75–230 and the journey takes 5h 39m.
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $55–390
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $35–250
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–410
Flights from John F. Kennedy International Airport to Ithaca Tompkins Regional Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $35–250
- Website
- aa.com
Flights from Laguardia Airport to Rochester via Boston
- Ave. Duration
- 3h 46m
- When
- Saturday
- Estimated price
- $80–470
Flights from Philadelphia International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $75–550
- Website
- united.com
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $80–470
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $35–250
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Syracuse
- Ave. Duration
- 5h 39m
- Frequency
- Once daily
- Estimated price
- $75–230
- Website
- VIA Rail
- Escape
- $75–180
- Business
- $110–220
- Business Plus
- $120–230
- Economy
- $85–190
- Economy Plus
- $95–200
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 18m
- Frequency
- Once daily
- Estimated price
- $21–160
- Website
- VIA Rail
- Escape
- $21–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $23–80
- Economy Plus
- $26–85
- Phone
- +1-718-217-5477
- Website
- Long Island Rail Road
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 21 min
- Frequency
- Every 10 minutes
- Estimated price
- $5–9
- Website
- Long Island Rail Road
- Schedules at
- Long Island Rail Road Schedules
- Off-Peak
- $5–8
- Peak
- $5–9
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 21m
- Frequency
- Every 30 minutes
- Estimated price
- $45–80
- Website
- Amtrak
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to 30th Street Station
- Ave. Duration
- 1h 9m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Ave. Duration
- 5h 20m
- Frequency
- Every 4 hours
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Bus from Ithaca to Syracuse Bus Station
- Ave. Duration
- 1h 15m
- Frequency
- 3 times a week
- Estimated price
- $10–15
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Port Authority Bus Terminal to Syracuse Bus Station
- Saver
- $40–150
- Flexible
- $70–160
- Phone
- 877-690-5116
- Website
- MTA
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- MTA
- Schedules at
- MTA scheduled
- Website
- MTA: World Cup 2026
- Standard Fare
- $3–8
Want to know more about travelling around United States
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Booking & Getting There
Manhattan to Destiny USA bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Manhattan to Destiny USA train services, operated by VIA Rail, arrive at Syracuse station.
Yes, the driving distance between Manhattan to Destiny USA is 254 miles. It takes approximately 4h 37m to drive from Manhattan to Destiny USA.
Book your Manhattan to Destiny USA train tickets online with Omio.
Book your Manhattan to Destiny USA bus tickets online with Omio and FlixBus.
There are 117+ hotels available in Destiny USA.























