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How to get fromManhattan to Florence Stationby bus (Greyhound), train (Amtrak), car, plane, bus, bus (Flixbus, Greyhound), or train

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There are 11 ways to get from Manhattan to Florence Station by bus (Greyhound), train (Amtrak), car, plane, bus, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Port Authority Bus Terminal to Raleigh Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    14h 8m
    $102–196

  2. Train (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Florence Stationtrain train Palmetto / ...
    14h 41m
    $200–420

  3. Drive 629.4 mi

    1. Drive from Manhattan to Florence Stationcar car 629.4 mi
    11h 6m
    $115–166

  4. Fly Newark Liberty International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Newark Liberty International Airport (EWR) to Charlotte Douglas International Airport (CLT)plane plane EWR - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 10m
    $272–620

  5. Bus via Fayetteville

    1. Take the bus from New York City Chinatown to Fayetteville Bus Stationbus bus FlixBus N2471 / ...
    2. Take the bus from Fayetteville Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    15h 48m
    $111–192

  6. Fly Laguardia Airport to Charlotte Douglas International Airport, bus

    1. Fly from Laguardia Airport (LGA) to Charlotte Douglas International Airport (CLT)plane plane LGA - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    9h 16m
    $155–650

  7. Fly Laguardia Airport to Wilmington International Airport, bus, train

    1. Fly from Laguardia Airport (LGA) to Wilmington International Airport (ILM)plane plane LGA - ILM
    2. Take the bus from Wilmington Cape Fear Public Transit to Fayetteville Bus Stationbus bus
    3. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    9h 47m
    $140–575

  8. Fly Laguardia Airport to Myrtle Beach, bus, train

    1. Fly from Laguardia Airport (LGA) to Myrtle Beach (MYR)plane plane LGA - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 26m
    $128–514

  9. Fly Newark Liberty International Airport to Myrtle Beach, bus, train

    1. Fly from Newark Liberty International Airport (EWR) to Myrtle Beach (MYR)plane plane EWR - MYR
    2. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    3. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    9h 31m
    $425–884

  10. Fly Laguardia Airport to Columbia, bus

    1. Fly from Laguardia Airport (LGA) to Columbia (CAE)plane plane LGA - CAE
    2. Take the bus from Columbia, SC to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    10h
    $262–1,265

  11. Fly Newark Liberty International Airport to Raleigh-Durham International Airport, train

    1. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    2. Take the train from Raleigh Union Station to Selma Stationtrain train
    3. Take the train from Selma Station to Florence Stationtrain train
    10h 16m
    $262–1,139

Manhattan to Florence Station by train (Amtrak)

Calendar14Weekly Trains
Duration14h 41mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Florence Station.ExpandLaunch map view
  • Distance: 686.8 mi
  • Duration: 14h 8m

What companies run services between Manhattan, NY, USA and Florence Station, SC, USA?

You can take a bus from Port Authority Bus Terminal to Florence Station via Raleigh Bus Station and Florence Bus Station in around 14h 8m. Alternatively, Amtrak operates a train from Ny Moynihan Train Hall At Penn Station to Florence Station twice daily. Tickets cost $200–420 and the journey takes 14h 41m.

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