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How to get fromManhattan to Louisvilleby plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

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There are 9 ways to get from Manhattan to Louisville by plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Newark Liberty International Airport to Louisville International Airport

    best
    1. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    4h 59m
    $116–530

  2. Bus via Columbus

    1. Take the bus from Port Authority Bus Terminal to Wilson & Ferrell Shell Station - Columbusbus bus Greyhound US0421
    2. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Louisville, KY Bus Stationbus bus Cleveland
    19h 15m
    $119–243

  3. Train, bus (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    26h 40m
    $333–658

  4. Drive 733.6 mi

    1. Drive from Manhattan to Louisvillecar car 733.6 mi
    13h 1m
    $134–194

  5. Fly Laguardia Airport to Louisville International Airport

    1. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    5h 4m
    $124–660

  6. Fly Laguardia Airport to Blue Grass Airport, drive

    1. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 56m
    $186–976

  7. Fly Newark Liberty International Airport to Covington, bus

    1. Fly from Newark Liberty International Airport (EWR) to Covington (CVG)plane plane EWR - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    7h 26m
    $291–1,174

  8. Fly Laguardia Airport to Covington, bus

    1. Fly from Laguardia Airport (LGA) to Covington (CVG)plane plane LGA - CVG
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus
    7h 29m
    $134–754

  9. Bus

    1. Take the bus from New York Midtown to Cincinnatibus bus FlixBus N2642
    2. Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus bus Cleveland
    19h 17m
    $124–235

Manhattan to Louisville by bus

Calendar14Weekly Buses
Duration19h 15mAverage Duration
Ticket$119Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Louisville.ExpandLaunch map view
  • Distance: 660.5 mi
  • Duration: 4h 59m

What companies run services between Manhattan, NY, USA and Louisville, KY, USA?

United Airlines, Delta, and American Airlines fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a bus from Port Authority Bus Terminal to Louisville, KY Bus Station via N Wilson Rd & Ferrell Pl - Columbus in around 19h 15m.

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