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How to get fromManhattan to Louisvilleby bus, plane, bus (Greyhound, Amtrak), train, car, or bus (Flixbus, Amtrak)

Find Transport to Louisville

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There are 7 ways to get from Manhattan to Louisville by bus, plane, bus (Greyhound, Amtrak), train, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Newark Liberty International Airport, fly to Louisville International Airport

    best
    1. Take the bus from Port Authority Bus Terminal to Terminal Bbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    5h 11m
    $156–868

  2. Fly Laguardia Airport to Blue Grass Airport, drive

    cheapest
    1. Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane plane LGA - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 56m
    $106–576

  3. Bus

    1. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    20h
    $167–259

  4. Train, bus (Amtrak)

    1. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    26h 10m
    $541–841

  5. Drive  733.6 mi

    1. Drive from Manhattan to Louisvillecar car 733.6 mi
    13h
    $134–194

  6. Fly Laguardia Airport to Louisville International Airport

    1. Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane plane LGA - SDF
    5h 8m
    $174–1,010

  7. Bus via Reading

    1. Take the bus from New York Midtown to Cincinnatibus bus
    2. Take the bus from Cincinnati to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    23h 54m
    $158–304

Manhattan to Louisville by bus

Calendar14Weekly Buses
Duration20hAverage Duration
Ticket$167Cheapest Price
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Comparing Your Travel Options

Map of how to get from Manhattan to Louisville.ExpandLaunch map view
  • Distance: 708.6 mi
  • Duration: 5h 11m

What companies run services between Manhattan, NY, USA and Louisville, KY, USA?

You can take a bus from Port Authority Bus Terminal to Louisville, KY via Indianapolis Union Station in around 20h. Alternatively, Delta, United Airlines, and two other airlines fly from Laguardia Airport (LGA) to Louisville International Airport (SDF) every 3 hours.

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