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How to get fromManhattan to Panama Cityby plane, car, or train

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There are 7 ways to get from Manhattan to Panama City by plane, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Laguardia Airport to Northwest Florida Beaches International Airport

    best
    1. Fly from Laguardia Airport (LGA) to Northwest Florida Beaches International Airport (ECP)plane plane LGA - ECP
    5h 2m
    $188–687

  2. Fly John F. Kennedy International Airport to Destin–Fort Walton Beach Airport, drive

    cheapest
    1. Fly from John F. Kennedy International Airport (JFK) to Destin–Fort Walton Beach Airport (VPS)plane plane JFK - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    6h 5m
    $116–476

  3. Drive 1,136.4 mi

    1. Drive from Manhattan to Panama Citycar car 1,136.4 mi
    20h 34m
    $208–300

  4. Fly Newark Liberty International Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Newark Liberty International Airport (EWR) to Destin–Fort Walton Beach Airport (VPS)plane plane EWR - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    5h 57m
    $127–495

  5. Fly Laguardia Airport to Destin–Fort Walton Beach Airport, drive

    1. Fly from Laguardia Airport (LGA) to Destin–Fort Walton Beach Airport (VPS)plane plane LGA - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama Citycar car
    6h 9m
    $135–625

  6. Train to Philadelphia International Airport, fly to Northwest Florida Beaches International Airport

    1. Take the train from Ny Moynihan Train Hall At Penn Station to 30th Street Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Northwest Florida Beaches International Airport (ECP)plane plane PHL - ECP
    6h 19m
    $209–1,279

  7. Fly Laguardia Airport to Pensacola International Airport, drive

    1. Fly from Laguardia Airport (LGA) to Pensacola International Airport (PNS)plane plane LGA - PNS
    2. Drive from Pensacola-Airport-PNS to Panama Citycar car
    7h 1m
    $132–586

Laguardia Airport (LGA) to Northwest Florida Beaches International Airport (ECP) flights

Calendar65Weekly Planes
Duration5h 10mAverage Duration
Ticket$119Cheapest Price
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Questions & Answers

Map of how to get from Manhattan to Panama City.ExpandLaunch map view
  • Distance: 1,012.1 mi
  • Duration: 5h 2m

What companies run services between Manhattan, NY, USA and Panama City, FL, USA?

Delta, American Airlines, and Southwest Airlines fly from Laguardia Airport (LGA) to Northwest Florida Beaches International Airport (ECP) every 3 hours.

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