There are 7 ways to get from Manhattan to Syracuse, Ny by bus (Flixbus), train, car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from New York to Syracusebus Adt N816 / ...
4h 45m$45–80Train
- Take the train from New York Penn Station to Syracusetrain VIA Rail
5h 33m$75–240Drive 252.8 mi
- Drive from Manhattan to Syracuse, Nycar 252.8 mi
4h 38m$47–67Bus to Laguardia Airport, fly to Syracuse Hancock International Airport
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
3h 58m$96–684Fly John F. Kennedy International Airport to Syracuse Hancock International Airport
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
4h 11m$87–535Fly Laguardia Airport to Rochester, train
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 21m$132–789Fly Newark Liberty International Airport to Rochester, train
- Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane EWR - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 21m$529–1,809
Manhattan to Syracuse, Ny by bus
Questions & Answers
The cheapest way to get from Manhattan to Syracuse, Ny is to drive which costs $45 - $70 and takes 4h 38m.
The fastest way to get from Manhattan to Syracuse, Ny is to bus and fly which takes 3h 58m and costs $95 - $700.
Yes, there is a direct bus departing from New York and arriving at Syracuse. Services depart hourly, and operate every day. The journey takes approximately 4h 45m.
Yes, there is a direct train departing from New York Penn Station station and arriving at Syracuse. Services depart once daily, and operate every day. The journey takes approximately 5h 33m.
The distance between Manhattan and Syracuse, Ny is 301 miles. The road distance is 254.3 miles.
The best way to get from Manhattan to Syracuse, Ny without a car is to bus which takes 4h 45m and costs $45 - $80.
The bus from New York to Syracuse takes 4h 45m including transfers and departs hourly.
Manhattan to Syracuse, Ny bus services, operated by Trailways, depart from New York station.
Manhattan to Syracuse, Ny train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Manhattan to Syracuse, Ny is to bus which takes 4h 45m and costs $45 - $80. Alternatively, you can train, which costs $75 - $240 and takes 5h 33m, you could also fly, which costs $85 - $550 and takes 4h 11m.
What companies run services between Manhattan, NY, USA and Syracuse, Ny, NY, USA?
Trailways operates a bus from New York to Syracuse every 4 hours. Tickets cost $40–180 and the journey takes 4h 45m. Two other operators also service this route. Alternatively, VIA Rail operates a train from New York Penn Station to Syracuse once daily. Tickets cost $75–240 and the journey takes 5h 33m.
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $90–650
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $70–490
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $90–600
- Website
- united.com
Flights from Laguardia Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $130–700
Flights from Newark Liberty International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $70–470
Flights from Newark Liberty International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $100–600
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $70–490
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Syracuse
- Ave. Duration
- 5h 33m
- Frequency
- Once daily
- Estimated price
- $75–240
- Website
- https://www.viarail.ca/en
- Escape
- $75–180
- Business
- $110–230
- Business Plus
- $120–240
- Economy
- $85–190
- Economy Plus
- $95–200
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–160
- Website
- https://www.viarail.ca/en
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $24–80
- Economy Plus
- $26–85
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–160
- Website
- https://www.viarail.ca/en
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $24–80
- Economy Plus
- $26–85
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $25–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from New York to Syracuse
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from New York to Syracuse
- Ave. Duration
- 5h 20m
- Frequency
- Every 3 hours
- Estimated price
- $70–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–110
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New York to Syracuse
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- $45–80
- Schedules at
- flixbus.com
- Phone
- 877-690-5116
- Website
- mta.info
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- https://www.mta.info/
- Schedules at
- https://www.mta.info/schedules
- Website
- https://www.mta.info/world-cup-2026-new-york-new-jersey
- Standard Fare
- $3–8
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More Questions & Answers
Manhattan to Syracuse, Ny bus services, operated by Trailways, arrive at Syracuse station.
Manhattan to Syracuse, Ny train services, operated by VIA Rail, arrive at Syracuse station.
Yes, the driving distance between Manhattan to Syracuse, Ny is 254 miles. It takes approximately 4h 38m to drive from Manhattan to Syracuse, Ny.
Book your Manhattan to Syracuse, Ny train tickets online with Omio.
Book your Manhattan to Syracuse, Ny bus tickets online with Omio and FlixBus.
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