There are 8 ways to get from Manhattan to Syracuse, Ny by bus (Greyhound), train, car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from New York to Syracusebus Adt N816-D / ...
4h 45m$45–75Train
- Take the train from New York Penn Station to Syracusetrain VIA Rail
5h 33m$75–230Drive 253 mi
- Drive from Manhattan to Syracuse, Nycar 253 mi
4h 38m$47–67Fly Laguardia Airport to Syracuse Hancock International Airport
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
3h 52m$116–834Fly John F. Kennedy International Airport to Syracuse Hancock International Airport
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
4h 2m$97–645Fly Laguardia Airport to Rochester, train
- Fly from Laguardia Airport (LGA) to Rochester (ROC)plane LGA - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 15m$152–989Bus to Newark Liberty International Airport, fly to Rochester, train
- Take the bus from Port Authority Bus Terminal to Terminal Bbus
- Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane EWR - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
5h 26m$154–897Fly John F. Kennedy International Airport to Ithaca Tompkins Regional Airport, bus
- Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)plane JFK - ITH
- Take the bus from Ithaca to Syracuse Bus Stationbus
6h 27m$58–322
Manhattan to Syracuse, Ny by bus
Comparing Your Travel Options
The cheapest way to get from Manhattan to Syracuse, Ny is to bus which costs $45 - $75 and takes 4h 45m.
The fastest way to get from Manhattan to Syracuse, Ny is to fly which takes 3h 52m and costs $110 - $850.
Yes, there is a direct bus departing from New York and arriving at Syracuse. Services depart every two hours, and operate every day. The journey takes approximately 4h 45m.
Yes, there is a direct train departing from New York Penn Station station and arriving at Syracuse. Services depart once daily, and operate every day. The journey takes approximately 5h 33m.
The distance between Manhattan and Syracuse, Ny is 301 miles. The road distance is 254.5 miles.
The best way to get from Manhattan to Syracuse, Ny without a car is to bus which takes 4h 45m and costs $45 - $75.
The bus from New York to Syracuse takes 4h 45m including transfers and departs every two hours.
Manhattan to Syracuse, Ny bus services, operated by Trailways, depart from New York station.
Manhattan to Syracuse, Ny train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Manhattan to Syracuse, Ny is to bus which takes 4h 45m and costs $45 - $75. Alternatively, you can train, which costs $75 - $230 and takes 5h 33m, you could also fly, which costs $110 - $850 and takes 3h 52m.
What companies run services between Manhattan, NY, USA and Syracuse, Ny, NY, USA?
Trailways operates a bus from New York to Syracuse every 4 hours. Tickets cost $40–180 and the journey takes 4h 45m. Greyhound USA also services this route every 4 hours. Alternatively, VIA Rail operates a train from New York Penn Station to Syracuse once daily. Tickets cost $75–230 and the journey takes 5h 33m.
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $110–800
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $80–600
Flights from Laguardia Airport to Rochester
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $110–800
Flights from John F. Kennedy International Airport to Ithaca Tompkins Regional Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $35–290
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Syracuse
- Ave. Duration
- 5h 33m
- Frequency
- Once daily
- Estimated price
- $75–230
- Website
- VIA Rail
- Escape
- $75–180
- Business
- $110–220
- Business Plus
- $120–230
- Economy
- $85–190
- Economy Plus
- $95–190
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–160
- Website
- VIA Rail
- Escape
- $21–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $23–80
- Economy Plus
- $26–85
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–160
- Website
- VIA Rail
- Escape
- $21–70
- Business
- $50–150
- Business Plus
- $60–160
- Economy
- $23–80
- Economy Plus
- $26–85
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from New York to Syracuse
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–180
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $40–170
- Flexible
- $80–180
Want to know more about travelling around United States
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Booking & Getting There
Manhattan to Syracuse, Ny bus services, operated by Trailways, arrive at Syracuse station.
Manhattan to Syracuse, Ny train services, operated by VIA Rail, arrive at Syracuse station.
Yes, the driving distance between Manhattan to Syracuse, Ny is 255 miles. It takes approximately 4h 38m to drive from Manhattan to Syracuse, Ny.
Book your Manhattan to Syracuse, Ny train tickets online with Omio.
Book your Manhattan to Syracuse, Ny bus tickets online with Omio and FlixBus.
There are 119+ hotels available in Syracuse, Ny.