There are 6 ways to get from Manhattan to Syracuse University by bus, train, car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Port Authority Bus Terminal to Syracuse Univbus 316
4h 39m$35–160Train
- Take the train from New York Penn Station to Syracusetrain VIA Rail
6h 37m$79–240Drive 250.2 mi
- Drive from Manhattan to Syracuse Universitycar 250.2 mi
4h 35m$46–66Bus to Laguardia Airport, fly
- Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus
- Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane LGA - SYR
4h 51m$94–665Bus via Regional Transportation Center (Flixbus)
- Take the bus from New York Midtown to Syracuse Bus Stationbus FlixBus N2686 / ...
6h 14m$47–82Train to John F. Kennedy International Airport, fly
- Take the train from Grand Central Terminal to Jamaicatrain
- Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane JFK - SYR
5h 5m$85–516
Manhattan to Syracuse University by bus and foot
Questions & Answers
The cheapest way to get from Manhattan to Syracuse University is to drive which costs $45 - $70 and takes 4h 35m.
The fastest way to get from Manhattan to Syracuse University is to drive which takes 4h 35m and costs $45 - $70.
Yes, there is a direct bus departing from Port Authority Bus Terminal and arriving at Syracuse Univ. Services depart once daily, and operate Monday, Thursday, Friday and Sunday. The journey takes approximately 4h 35m.
No, there is no direct train from Manhattan station to Syracuse University. However, there are services departing from New York Penn Station and arriving at Syracuse via . The journey, including transfers, takes approximately 6h 37m.
The distance between Manhattan and Syracuse University is 260 miles. The road distance is 251.7 miles.
The best way to get from Manhattan to Syracuse University without a car is to bus which takes 4h 39m and costs $35 - $160.
The bus from Port Authority Bus Terminal to Syracuse Univ takes 4h 35m including transfers and departs once daily.
Manhattan to Syracuse University bus services, operated by Trailways, depart from Port Authority Bus Terminal station.
Manhattan to Syracuse University train services, operated by VIA Rail, depart from New York Penn Station.
The best way to get from Manhattan to Syracuse University is to bus which takes 4h 39m and costs $35 - $160. Alternatively, you can train, which costs $75 - $240 and takes 6h 37m.
What companies run services between Manhattan, NY, USA and Syracuse University, NY, USA?
Trailways operates a bus from Port Authority Bus Terminal to Syracuse Univ once daily. Tickets cost $35–160 and the journey takes 4h 35m. Alternatively, VIA Rail operates a train from New York Penn Station to Syracuse once daily. Tickets cost $75–240 and the journey takes 5h 33m.
- Website
- delta.com
Flights from Laguardia Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $90–650
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $70–490
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $70–490
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from New York Penn Station to Syracuse
- Ave. Duration
- 5h 33m
- Frequency
- Once daily
- Estimated price
- $75–240
- Website
- https://www.viarail.ca/en
- Escape
- $75–180
- Business
- $110–230
- Business Plus
- $120–240
- Economy
- $85–190
- Economy Plus
- $95–200
- Phone
- +1-718-217-5477
- Website
- mta.info
Train from Grand Central Terminal to Jamaica
- Ave. Duration
- 21 min
- Frequency
- Every 15 minutes
- Estimated price
- $5–9
- Website
- https://www.mta.info/agency/long-island-rail-road
- Schedules at
- https://www.mta.info/agency/long-island-rail-road/timetables
- Off-Peak
- $5–8
- Peak
- $5–9
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Port Authority Bus Terminal to Syracuse Univ
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $35–160
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $35–150
- Flexible
- $70–160
- Phone
- 877-690-5116
- Website
- mta.info
Bus from E 125 St/Lexington Av to Laguardia Rd/94 St
- Ave. Duration
- 24 min
- Frequency
- Every 10 minutes
- Estimated price
- $3–8
- Website
- https://www.mta.info/
- Schedules at
- https://www.mta.info/schedules
- Website
- https://www.mta.info/world-cup-2026-new-york-new-jersey
- Standard Fare
- $3–8
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from New York Midtown to Syracuse Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Schedules at
- flixbus.com
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More Questions & Answers
Manhattan to Syracuse University bus services, operated by Trailways, arrive at Syracuse Univ station.
Manhattan to Syracuse University train services, operated by VIA Rail, arrive at Syracuse station.
Yes, the driving distance between Manhattan to Syracuse University is 252 miles. It takes approximately 4h 35m to drive from Manhattan to Syracuse University.
Book your Manhattan to Syracuse University bus tickets online with Omio.
There are 112+ hotels available in Syracuse University.











