There are 3 ways to get from Manila to Santa Isabela by plane, taxi, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Antonio Maceo International Airport, taxi
best- Fly from Ninoy Aquino International Airport (MNL) to Antonio Maceo International Airport (SCU)plane MNL - SCU
- Take the taxi from Antonio Maceo International Airport (SCU) to Santa Isabelataxi
26h 56m$937–2,448Fly to Ignacio Agramonte International Airport, bus
cheapest- Fly from Ninoy Aquino International Airport (MNL) to Ignacio Agramonte International Airport (CMW)plane MNL - CMW
- Take the bus from Camaguey to Palma Sorianobus
35h 38m$520–1,426Fly to Frank País International Airport, bus
- Fly from Ninoy Aquino International Airport (MNL) to Frank País International Airport (HOG)plane MNL - HOG
- Take the bus from Holguin Airport to Bayamobus
- Take the bus from Bayamo to Los Benitezbus
34h 22m$624–1,632
Ninoy Aquino International Airport (MNL) to Antonio Maceo International Airport (SCU) flights
Comparing Your Travel Options
The cheapest way to get from Manila to Santa Isabela is to fly and bus which costs $500 - $1,500 and takes 35h 38m.
The fastest way to get from Manila to Santa Isabela is to fly and taxi which takes 26h 56m and costs $900 - $2,500.
The distance between Manila and Santa Isabela is 15818 km.
It takes approximately 26h 56m to get from Manila to Santa Isabela, including transfers.
Santa Isabela is 13h behind Manila. It is currently 2:21 PM in Manila and 1:21 AM in Santa Isabela.
What companies run services between Manila, Philippines and Santa Isabela, Cuba?
There is no direct connection from Manila to Santa Isabela. However, you can take the bus to NAIA Terminal 2, walk to Ninoy Aquino International Airport (MNL) airport, fly to Antonio Maceo International Airport (SCU), then take the taxi to Santa Isabela. Alternatively, you can take the bus to NAIA Terminal 2, walk to Ninoy Aquino International Airport (MNL) airport, fly to Frank País International Airport (HOG), walk to Holguin Airport, take the bus to Bayamo, take the bus to Los Benitez, then take the taxi to Santa Isabela.
- Website
- aa.com
Flights from Ninoy Aquino International Airport to Antonio Maceo International Airport via San Francisco, Miami
- Ave. Duration
- 23h 50m
- When
- Wednesday to Sunday
- Estimated price
- $850–2,900
Flights from Ninoy Aquino International Airport to Antonio Maceo International Airport via Seattle, Miami
- Ave. Duration
- 24h 35m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $900–2,400
Flights from Ninoy Aquino International Airport to Antonio Maceo International Airport via Los Angeles, Miami
- Ave. Duration
- 25h
- When
- Wednesday to Sunday
- Estimated price
- $900–2,400
Flights from Ninoy Aquino International Airport to Antonio Maceo International Airport via Chicago O'Hare, Miami
- Ave. Duration
- 30h 35m
- When
- Wednesday and Friday
- Estimated price
- $900–2,400
Flights from Ninoy Aquino International Airport to Frank País International Airport via San Francisco, Miami
- Ave. Duration
- 27h 35m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $550–2,000
Flights from Ninoy Aquino International Airport to Frank País International Airport via Seattle, Miami
- Ave. Duration
- 28h 20m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $600–1,600
Flights from Ninoy Aquino International Airport to Frank País International Airport via Los Angeles, Miami
- Ave. Duration
- 28h 45m
- When
- Every day
- Estimated price
- $600–1,700
Flights from Ninoy Aquino International Airport to Frank País International Airport via Toronto, Miami
- Ave. Duration
- 30h 50m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $600–1,600
Flights from Ninoy Aquino International Airport to Frank País International Airport via New York JFK, Miami
- Ave. Duration
- 30h 50m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- $600–1,700
Flights from Ninoy Aquino International Airport to Frank País International Airport via Chicago O'Hare, Miami
- Ave. Duration
- 34h 20m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $600–1,600
Flights from Ninoy Aquino International Airport to Ignacio Agramonte International Airport via San Francisco, Miami
- Ave. Duration
- 27h 30m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $500–1,700
Flights from Ninoy Aquino International Airport to Ignacio Agramonte International Airport via Seattle, Miami
- Ave. Duration
- 28h 15m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $500–1,400
Flights from Ninoy Aquino International Airport to Ignacio Agramonte International Airport via Los Angeles, Miami
- Ave. Duration
- 28h 40m
- When
- Every day
- Estimated price
- $550–1,500
Flights from Ninoy Aquino International Airport to Ignacio Agramonte International Airport via Chicago O'Hare, Miami
- Ave. Duration
- 34h 15m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $500–1,400
- Website
- vivaaerobus.com
Flights from Ninoy Aquino International Airport to Ignacio Agramonte International Airport via San Francisco, Cancun
- Ave. Duration
- 33h 40m
- When
- Tuesday
- Estimated price
- $500–1,700
Flights from Ninoy Aquino International Airport to Ignacio Agramonte International Airport via Los Angeles, Cancun
- Ave. Duration
- 34h 55m
- When
- Tuesday
- Estimated price
- $500–1,700
- Phone
- +53 59 89 0616
- [email protected]
- Website
- Viazul
Bus from Holguin Airport to Bayamo
- Ave. Duration
- 1h 5m
- Frequency
- 5 times a day
- Estimated price
- $8–12
- Website
- Viazul
- Phone
- +53 7873 7373
- [email protected]
- Website
- Ómnibus Nacionales
Bus from Bayamo to Los Benitez
- Ave. Duration
- 1h 8m
- Frequency
- Once daily
- Estimated price
- $1
- Schedules at
- Ómnibus Nacionales
Bus from Camaguey to Palma Soriano
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $2–4
- Schedules at
- Ómnibus Nacionales
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