There are 7 ways to get from Manitowoc to Mayo Clinic by bus (Greyhound), car, bus, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Manitowoc to Milwaukee Intermodal Stationbus Greyhound US0150S
- Take the bus from Milwaukee to Rochesterbus Jefferson Lines 966
8h 32m$91–144Drive 274.2 mi
cheapest- Drive from Manitowoc to Mayo Cliniccar 274.2 mi
5h 35m$50–73Bus to Green Bay, fly to Rochester
- Take the bus from Manitowoc to Green Bay Transit Centerbus
- Fly from Green Bay (GRB) to Rochester (RST)plane GRB - RST
6h 34m$101–446Taxi to Appleton International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the taxi from Manitowoc to Appleton International Airport (ATW)taxi
- Fly from Appleton International Airport (ATW) to Minneapolis–Saint Paul International Airport (MSP)plane ATW - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 47m$217–562Bus to Green Bay, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Manitowoc to Green Bay Transit Centerbus
- Fly from Green Bay (GRB) to Minneapolis–Saint Paul International Airport (MSP)plane GRB - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
6h 27m$155–506Bus to General Mitchell International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the bus from Manitowoc to Milwaukee Intermodal Stationbus
- Fly from General Mitchell International Airport (MKE) to Minneapolis–Saint Paul International Airport (MSP)plane MKE - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 48m$673–1,108Bus, bus to Chicago O'Hare International Airport, fly to Rochester
- Take the bus from Manitowoc to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
8h 9m$100–396
Green Bay (GRB) to Rochester (RST) flights
Comparing Your Travel Options
The cheapest way to get from Manitowoc to Mayo Clinic is to drive which costs $50 - $75 and takes 5h 35m.
The fastest way to get from Manitowoc to Mayo Clinic is to drive which takes 5h 35m and costs $50 - $75.
No, there is no direct bus from Manitowoc to Mayo Clinic. However, there are services departing from Manitowoc and arriving at Rochester via Milwaukee. The journey, including transfers, takes approximately 8h 32m.
The distance between Manitowoc and Mayo Clinic is 364 miles. The road distance is 275.8 miles.
The best way to get from Manitowoc to Mayo Clinic without a car is to bus which takes 8h 32m and costs $90 - $150.
It takes approximately 8h 32m to get from Manitowoc to Mayo Clinic, including transfers.
Manitowoc to Mayo Clinic bus services, operated by Greyhound USA, depart from Manitowoc station.
Manitowoc to Mayo Clinic bus services, operated by Greyhound USA, arrive at Milwaukee Intermodal Station.
Yes, the driving distance between Manitowoc to Mayo Clinic is 276 miles. It takes approximately 5h 35m to drive from Manitowoc to Mayo Clinic.
There are 77+ hotels available in Mayo Clinic.
What companies run services between Manitowoc, WI, USA and Mayo Clinic, MN, USA?
You can take a vehicle from Manitowoc to Mayo Clinic via Manitowoc, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 8h 32m.
- Website
- delta.com
Flights from Green Bay to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $50–330
Flights from Appleton International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $55–380
Flights from Green Bay to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $55–380
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Green Bay to Rochester via Chicago O'Hare International Airport
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $55–350
Flights from Chicago O'Hare International Airport to Rochester
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–270
- Website
- southwest.com
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 3h 12m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–600
- Website
- suncountry.com
Flights from General Mitchell International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 1h 19m
- When
- Sunday
- Estimated price
- $80–550
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Manitowoc to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Manitowoc to Green Bay Transit Center
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $6–10
- Website
- Greyhound
Bus from Manitowoc to Green Bay Transit Center
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $6–10
- Website
- Greyhound
Bus from Manitowoc to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
Bus from Manitowoc to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $13–21
- Website
- Greyhound
- Phone
- +1 989-725-5105
- Website
- Indian Trails
Bus from Manitowoc to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- Indian Trails
Bus from Manitowoc to Green Bay Transit Center
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $8–22
- Website
- Indian Trails
Bus from Manitowoc to Green Bay Transit Center
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $8–22
- Website
- Indian Trails
Bus from Manitowoc to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- Indian Trails
Bus from Manitowoc to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- Indian Trails
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $70–100
- Book at
- Jefferson Lines
- Adult
- $70–100
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- Groome Transportation - Rochester - MSP
- Phone
- (866) 912 6224
- [email protected]
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Website
- coachusa.com
- Ave. Duration
- 1h 15m
- Estimated price
- $110–140
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