There are 12 ways to get from Mannheim to Assisi by train, bus, train (Trenitalia), night train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the bus from Basel to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
12h 42m€125–244Train to Frankfurt, fly to Fiumicino International Airport, train
cheapest- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Fiumicino International Airport (FCO)plane FRA - FCO
- Take the train from Roma Termini to Assisitrain
9h 17m€74–201Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Chiassotrain Ec
- Take the train from Chiasso to Milano Lambratetrain Ec
- Take the train from Milano Lambrate to Assisitrain Ic
16h 24m€118–394Train, night train
- Take the train from Mannheim, Hauptbahnhof to München Hbftrain 11 / ...
- Take the nighttrain from Muenchen Hbf to Bologna Centralenighttrain Nj
- Take the train from Bologna Centrale to Assisitrain Ic
19h 5m€108–307Drive 1,058 km
- Drive from Mannheim to Assisicar 1,058 km
10h 15m€172–248Bus
- Take the bus from Mannheim, Zob to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
17h 32m€147–203Bus via Mannheim central bus station
- Take the bus from Mannheim central bus station to Florence Villa Constanza Bus Stationbus N77
- Take the bus from Florence Villa Constanza Bus Station to Assisibus 529
19h€101–150Train to Frankfurt, fly to Florence Peretola Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Assisitrain
9h 27m€150–367Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Assisitrain
9h 52m€133–345Train to Stuttgart Airport, fly to Fiumicino International Airport, train
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Fiumicino International Airport (FCO)plane STR - FCO
- Take the train from Roma Termini to Assisitrain
9h 49m€106–259Train to Frankfurt, fly to Milan Linate Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Milan Linate Airport (LIN)plane FRA - LIN
- Take the train from Milano P.Garibaldi to Perugiatrain
10h 57m€108–300Train to Frankfurt, fly to Venice Marco Polo Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Assisitrain
12h€143–337
Mannheim to Assisi by train and bus
Comparing Your Travel Options
The cheapest way to get from Mannheim to Assisi is to train and fly which costs €70 - €210 and takes 9h 17m.
The fastest way to get from Mannheim to Assisi is to train and fly which takes 9h 17m and costs €70 - €210.
No, there is no direct bus from Mannheim to Assisi. However, there are services departing from Mannheim, Zob and arriving at Assisi via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 17h 32m.
No, there is no direct train from Mannheim to Assisi. However, there are services departing from Mannheim, Hauptbahnhof and arriving at Assisi via Basel SBB, Chiasso and Milano Lambrate. The journey, including transfers, takes approximately 16h 24m.
The distance between Mannheim and Assisi is 1153 km. The road distance is 1058 km.
The best way to get from Mannheim to Assisi without a car is to train and bus which takes 12h 42m and costs €120 - €250.
It takes approximately 12h 42m to get from Mannheim to Assisi, including transfers.
Mannheim to Assisi bus services, operated by Onebus, depart from Mannheim, Zob station.
Mannheim to Assisi train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Mannheim to Assisi is to train which takes 16h 24m and costs €110 - €400. Alternatively, you can bus, which costs €140 - €210 and takes 17h 32m.
What companies run services between Mannheim, Germany and Assisi, Italy?
You can take a train from Mannheim, Hauptbahnhof to Via San Francesco via Basel SBB, Chiasso, Milano Lambrate, Assisi, and Assisi Stazione in around 16h 24m. Alternatively, you can take a bus from Mannheim, Zob to Assisi via Florence Villa Constanza Bus Station in around 17h 32m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €110–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €170–550
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €70–130
Flights from Frankfurt to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- €75–130
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €130–450
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–460
Flights from Stuttgart Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 50m
- When
- Monday to Saturday
- Estimated price
- €80–300
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–250
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 2h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–420
- Website
- ita-airways.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €110–550
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- €70–130
Flights from Frankfurt to Fiumicino International Airport via Milan Linate Airport
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €75–420
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €130–450
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €80–250
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €160–550
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €140–450
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €50–440
- Website
- eurowings.com
Flights from Stuttgart Airport to Fiumicino International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- €70–150
- Website
- condor.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–320
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 45m
- When
- Friday
- Estimated price
- €70–160
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 10m
- When
- Friday
- Estimated price
- €85–200
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- €85–350
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 20m
- When
- Monday and Saturday
- Estimated price
- €75–300
Flights from Stuttgart Airport to Fiumicino International Airport via Zurich
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- €70–290
- Website
- easyjet.com
Flights from Frankfurt to Fiumicino International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €45–120
Flights from Frankfurt to Milan Linate Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–140
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to München Hbf
- Ave. Duration
- 2h 42m
- Frequency
- Hourly
- Estimated price
- €55–130
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €18–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to München Hbf
- Ave. Duration
- 2h 45m
- Frequency
- 3 times a day
- Estimated price
- €35–75
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €11–23
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Chiasso
- Ave. Duration
- 3h 26m
- Frequency
- 4 times a day
- Estimated price
- €100–170
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Chiasso to Milano Lambrate
- Ave. Duration
- 53 min
- Frequency
- Twice a week
- Estimated price
- €18–30
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Chiasso
- Ave. Duration
- 3h 48m
- Frequency
- Once daily
- Estimated price
- €21–28
- Schedules at
- SBB GmbH
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Lambrate to Assisi
- Ave. Duration
- 5h 49m
- Frequency
- Once daily
- Estimated price
- €50–95
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Assisi
- Ave. Duration
- 3h 31m
- Frequency
- Once daily
- Estimated price
- €29–55
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €19–35
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Assisi
- Ave. Duration
- 3h 31m
- Frequency
- Once daily
- Estimated price
- €29–55
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- €19–35
- Website
- Trenitalia Intercity
- Phone
- +49 221 800 20 80
- [email protected]
- Website
- MSM Partyzug
Train from Mannheim, Hauptbahnhof to München Hbf
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Schedules at
- MSM Partyzug
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Muenchen Hbf to Bologna Centrale
- Ave. Duration
- 9h 39m
- Frequency
- Once daily
- Estimated price
- €40–120
- Website
- Nightjet
- Sleeper Carriage
- €100–120
- Couchette Carriage
- €70–85
- Seating Carriage
- €40–50
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 46m
- Frequency
- Every 4 hours
- Estimated price
- €21–29
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Firenze S.M.N. to Assisi
- Ave. Duration
- 2h 46m
- Frequency
- Every 4 hours
- Estimated price
- €21–29
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano P.Garibaldi to Perugia
- Ave. Duration
- 3h 42m
- Frequency
- 6 times a week
- Estimated price
- €60–110
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €29–50
- Website
- Italo Treno
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Basel to Florence Villa Constanza Bus Station
- Ave. Duration
- 5h 46m
- Frequency
- Once a week
- Estimated price
- €80–120
- Website
- Onebus
Bus from Mannheim, Zob to Florence Villa Constanza Bus Station
- Ave. Duration
- 13h 57m
- Frequency
- Once a week
- Estimated price
- €130–180
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €15–24
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €15–24
- Website
- Flixbus
Bus from Mannheim central bus station to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 25m
- Frequency
- Once daily
- Estimated price
- €85–130
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Assisi
- Ave. Duration
- 2h 35m
- Frequency
- 5 times a week
- Estimated price
- €15–24
- Website
- Flixbus
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Booking & Getting There
Mannheim to Assisi bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Mannheim to Assisi train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mannheim to Assisi is 1058 km. It takes approximately 10h 15m to drive from Mannheim to Assisi.
Book your Mannheim to Assisi bus tickets online with Omio.
There are 2391+ hotels available in Assisi.











































