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How to get fromMannheim to Brindisiby train, plane, train (Trenitalia), bus, night train, or car

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There are 7 ways to get from Mannheim to Brindisi by train, plane, train (Trenitalia), bus, night train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Brindisi Airport (BDS)plane plane FRA - BDS
    4h 21m
    €98–299

  2. Train

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Mediopadana R.Emiliatrain train
    5. Take the train from Reggio Emilia Av to Brindisitrain train Fr
    17h 25m
    €204–792

  3. Bus

    1. Take the bus from Ludwigshafen ZOB to Baribus bus
    2. Take the bus from Bari Largo Sorrentino to Brindisi Strada Stratale Via Appiabus bus 2938R
    19h 43m
    €147–202

  4. Train, night train

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 47 / ...
    2. Take the nighttrain from Stuttgart Hbf to Padovanighttrain night train Nj
    3. Take the train from Padova to Brindisitrain train Fr
    24h 43m
    €182–462

  5. Train to Stuttgart Airport, fly

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Brindisi Airport (BDS)plane plane STR - BDS
    5h 8m
    €100–337

  6. Train, bus

    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train S9 / ...
    2. Take the bus from Karlsruhe central train station to Baribus bus
    3. Take the bus from Bari FS Park - Via Capruzzi to Brindisi Istituto Professionale Falconebus bus
    26h 39m
    €139–261

  7. Drive  1,581.8 km

    1. Drive from Mannheim to Brindisicar car 1,581.8 km
    14h 42m
    €250–361

Mannheim to Brindisi by train and night train

Calendar7Weekly Services
Duration24h 43mAverage Duration
Ticket€182Cheapest Price
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Questions & Answers

Map of how to get from Mannheim to Brindisi.ExpandLaunch map view
  • Distance: 1,345.3 km
  • Duration: 4h 21m

What companies run services between Mannheim, Germany and Brindisi, Italy?

You can take a train from Mannheim, Hauptbahnhof to Brindisi via Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 17h 25m. Alternatively, you can take a bus from Ludwigshafen ZOB to Brindisi Strada Stratale Via Appia via Bari and Bari Largo Sorrentino in around 19h 43m.

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