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How to get fromMannheim to Brindisiby train, plane, train (Trenitalia), bus, night train, car, or car train

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There are 8 ways to get from Mannheim to Brindisi by train, plane, train (Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Brindisi Airport (BDS)plane plane FRA - BDS
    4h 36m
    €98–285
  2. Train

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Reggio Emilia Avtrain train Fr
    5. Take the train from Reggio Emilia Av to Brindisitrain train Fr
    17h 8m
    €215–845
  3. Bus

    1. Take the bus from Ludwigshafen ZOB to Baribus bus
    2. Take the bus from Bari Largo Sorrentino to Brindisi Strada Stratale Via Appiabus bus 2938R
    19h 43m
  4. Train, night train

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train 11 / ...
    2. Take the night train from Stuttgart Hbf to Padovanighttrain night train Nj
    3. Take the train from Padova to Brindisitrain train Fr
    24h 42m
    €192–482
  5. Train to Stuttgart Airport, fly

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Brindisi Airport (BDS)plane plane STR - BDS
    5h 9m
    €101–320
  6. Train, bus

    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train 12 / ...
    2. Take the bus from Karlsruhe central train station to Baribus bus
    3. Take the bus from Bari FS Park - Via Capruzzi to Brindisi Istituto Professionale Falconebus bus
    25h 22m
    €144–282
  7. Drive 1,581.8 km

    1. Drive from Mannheim to Brindisicar car 1,581.8 km
    14h 41m
    €248–359
  8. Drive, car train

    1. Drive from Mannheim to Fuldacar car
    2. Take the car train from Fulda to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Brindisicar car
    22h 1m
    €291–417

Mannheim to Brindisi by train

Calendar73Weekly Trains
Duration17h 8mAverage Duration
Ticket€215Cheapest Price
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Questions & Answers

What companies run services between Mannheim, Germany and Brindisi, Italy?

You can take a train from Mannheim, Hauptbahnhof to Brindisi via Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 17h 8m. Alternatively, you can take a bus from Ludwigshafen ZOB to Brindisi Strada Stratale Via Appia via Bari and Bari Largo Sorrentino in around 19h 43m.

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