There are 8 ways to get from Mannheim to Brindisi by train, plane, train (Trenitalia), bus, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly
best- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Brindisi Airport (BDS)plane FRA - BDS
4h 36m€98–285Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Reggio Emilia Avtrain Fr
- Take the train from Reggio Emilia Av to Brindisitrain Fr
17h 8m€215–845Bus
- Take the bus from Ludwigshafen ZOB to Baribus
- Take the bus from Bari Largo Sorrentino to Brindisi Strada Stratale Via Appiabus 2938R
19h 43mTrain, night train
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain 11 / ...
- Take the night train from Stuttgart Hbf to Padovanighttrain Nj
- Take the train from Padova to Brindisitrain Fr
24h 42m€192–482Train to Stuttgart Airport, fly
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Brindisi Airport (BDS)plane STR - BDS
5h 9m€101–320Train, bus
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain 12 / ...
- Take the bus from Karlsruhe central train station to Baribus
- Take the bus from Bari FS Park - Via Capruzzi to Brindisi Istituto Professionale Falconebus
25h 22m€144–282Drive 1,581.8 km
- Drive from Mannheim to Brindisicar 1,581.8 km
14h 41m€248–359Drive, car train
- Drive from Mannheim to Fuldacar
- Take the car train from Fulda to Villach Hbfcartrain
- Drive from Villach Hbf to Brindisicar
22h 1m€291–417
Mannheim to Brindisi by train
Questions & Answers
The cheapest way to get from Mannheim to Brindisi is to train and fly which costs €100 - €320 and takes 5h 9m.
The fastest way to get from Mannheim to Brindisi is to train and fly which takes 4h 36m and costs €95 - €290.
No, there is no direct bus from Mannheim to Brindisi. However, there are services departing from Ludwigshafen ZOB and arriving at Brindisi Strada Stratale Via Appia via Bari Largo Sorrentino. The journey, including transfers, takes approximately 19h 43m.
No, there is no direct train from Mannheim to Brindisi. However, there are services departing from Mannheim, Hauptbahnhof and arriving at Brindisi via Basel SBB, Lugano, Milano Centrale and Reggio Emilia Av. The journey, including transfers, takes approximately 17h 8m.
The distance between Mannheim and Brindisi is 1345 km. The road distance is 1581.8 km.
The best way to get from Mannheim to Brindisi without a car is to train which takes 17h 8m and costs €210 - €850.
It takes approximately 4h 36m to get from Mannheim to Brindisi, including transfers.
Mannheim to Brindisi bus services, operated by Onebus, depart from Ludwigshafen ZOB station.
Mannheim to Brindisi train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Mannheim to Brindisi is to train which takes 17h 8m and costs €210 - €850. Alternatively, you can bus, which costs and takes 19h 43m.
What companies run services between Mannheim, Germany and Brindisi, Italy?
You can take a train from Mannheim, Hauptbahnhof to Brindisi via Basel SBB, Lugano, Milano Centrale, and Reggio Emilia Av in around 17h 8m. Alternatively, you can take a bus from Ludwigshafen ZOB to Brindisi Strada Stratale Via Appia via Bari and Bari Largo Sorrentino in around 19h 43m.
- Website
- lufthansa.com
Flights from Frankfurt to Brindisi Airport
- Ave. Duration
- 2h 5m
- When
- Monday and Friday
- Estimated price
- €95–270
Flights from Frankfurt to Brindisi Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Thursday
- Estimated price
- €220–1,000
Flights from Stuttgart Airport to Brindisi Airport via Munich
- Ave. Duration
- 4h
- When
- Thursday, Saturday, and Sunday
- Estimated price
- €120–1,000
- Website
- swiss.com
Flights from Frankfurt to Brindisi Airport via Zurich
- Ave. Duration
- 4h 10m
- When
- Saturday
- Estimated price
- €110–380
Flights from Stuttgart Airport to Brindisi Airport via Zurich
- Ave. Duration
- 4h 17m
- When
- Saturday, Wednesday, Friday, and Sunday
- Estimated price
- €110–470
- Website
- ita-airways.com
Flights from Stuttgart Airport to Brindisi Airport via Rome
- Ave. Duration
- 4h 21m
- When
- Tuesday, Thursday, Sunday, and Friday
- Estimated price
- €75–230
- Website
- airbus.com
Flights from Frankfurt to Brindisi Airport
- Ave. Duration
- 2h 5m
- When
- Monday and Friday
- Estimated price
- €95–270
- Website
- eurowings.com
Flights from Stuttgart Airport to Brindisi Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €75–230
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–60
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 11m
- Frequency
- Hourly
- Estimated price
- €45–200
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–85
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–85
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- €11–50
- Website
- https://int.bahn.de/en
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €8–17
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €28–60
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €12–25
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €12–25
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 28 min
- Frequency
- Once daily
- Estimated price
- €6–14
- Website
- https://www.ns.nl/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €90–280
- Website
- https://www.sbb.ch/en
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €27–85
- Website
- https://www.sbb.ch/en
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- sbb-deutschland.de
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- sbb-deutschland.de
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Reggio Emilia Av
- Ave. Duration
- 44 min
- Frequency
- Every 30 minutes
- Estimated price
- €22–45
- Schedules at
- trenitalia.com
Train from Reggio Emilia Av to Brindisi
- Ave. Duration
- 7h 4m
- Frequency
- Every 3 hours
- Estimated price
- €120–240
- Schedules at
- trenitalia.com
Train from Padova to Brindisi
- Ave. Duration
- 8h 8m
- Frequency
- 5 times a day
- Estimated price
- €130–260
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Reggio Emilia Av
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- €19–40
- Website
- https://www.italotreno.it/en
- Phone
- +43 (0) 51717
- Website
- nightjet.com
Night train from Stuttgart Hbf to Padova
- Ave. Duration
- 13h 56m
- Frequency
- Twice daily
- Estimated price
- €50–140
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €110–140
- Couchette Carriage
- €80–95
- Seating Carriage
- €50–60
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €14–24
- Website
- https://int.bahn.de/en
- Phone
- +49 621 830 1200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 6m
- Frequency
- 5 times a week
- Estimated price
- €13–19
- Schedules at
- suewex.de
- Phone
- +49 (0) 221 800 20 820
- [email protected]
- Website
- urlaubs-express.de
Car train from Fulda to Villach Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Once a week
- Estimated price
- €95–120
- Website
- https://urlaubs-express.de/?lang=en
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Ludwigshafen ZOB to Bari
- Ave. Duration
- 17h 36m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- 0832.871016
- [email protected]
- Website
- eliosautoservizi.com
Bus from Bari Largo Sorrentino to Brindisi Strada Stratale Via Appia
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €10–16
- Schedules at
- eliosautoservizi.com
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- https://www.flixbus.fr
Bus from Karlsruhe central train station to Bari
- Ave. Duration
- 21h 25m
- Frequency
- Once daily
- Estimated price
- €130–220
- Website
- https://www.flixbus.co.uk
Bus from Bari FS Park - Via Capruzzi to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 2h 30m
- Frequency
- Every 4 hours
- Estimated price
- €9–16
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Bari FS Park - Via Capruzzi to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 1h 39m
- Frequency
- 5 times a day
- Estimated price
- €7–14
- Website
- https://www.itabus.it/en/home
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Italian Lakes: Getting around by train
Read the travel guide
More Questions & Answers
Mannheim to Brindisi bus services, operated by Onebus, arrive at Bari station.
Mannheim to Brindisi train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mannheim to Brindisi is 1582 km. It takes approximately 14h 41m to drive from Mannheim to Brindisi.
Book your Mannheim to Brindisi train tickets online with Omio.
Book your Mannheim to Brindisi bus tickets online with Omio.
There are 1157+ hotels available in Brindisi.














































