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How to get fromMannheim to Brnoby train, bus, night train, car, or plane

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There are 10 ways to get from Mannheim to Brno by train, bus, night train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mannheim, Hauptbahnhof to München Hbftrain train 11 / ...
    2. Take the train from Muenchen Hbf Gl.5-10 to Salzburg Hbftrain train Re / ...
    3. Take the train from Salzburg Hbf to Wien Hbftrain train Rjx / ...
    4. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train Rj / ...
    9h 15m
    Kč 2,465–6,772
  2. Bus

    cheapest
    1. Take the bus from Mannheim central bus station to Brnobus bus N1309
    10h 15m
    Kč 1,600–2,400
  3. Night train, train

    1. Take the nighttrain from Mannheim Hbf to Praha Hlavni Nadrazinighttrain night train En
    2. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train Rj / ...
    12h 30m
    Kč 3,650–6,604
  4. Drive  715.3 km

    1. Drive from Mannheim to Brnocar car 715.3 km
    6h 8m
    Kč 3,157–4,559
  5. Train to Frankfurt, fly to Vienna International Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane plane FRA - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    6h 8m
    Kč 2,005–5,408
  6. Train to Frankfurt, fly to Václav Havel Airport Prague, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    3. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train
    7h 1m
    Kč 1,828–5,088
  7. Train to Stuttgart Airport, fly to Vienna International Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane plane STR - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    6h 46m
    Kč 2,276–7,628
  8. Train to Frankfurt, fly to Dresden Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    3. Take the train from Dresden-Neustadt to Brno hl.n.train train
    9h 14m
    Kč 3,942–8,500
  9. Train to Cologne Bonn Airport, fly to Vienna International Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Köln Hbftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Vienna International Airport (VIE)plane plane CGN - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 39m
    Kč 2,542–8,647
  10. Train to Frankfurt, fly to Linz Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Linz Airport (LNZ)plane plane FRA - LNZ
    3. Take the train from Linz/Donau Hbf to Wien Hbftrain train
    4. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    8h 17m
    Kč 3,172–6,970

Mannheim to Brno by train

Calendar185Weekly Trains
Duration9h 15mAverage Duration
TicketKč 2,465Cheapest Price
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Comparing Your Travel Options

What companies run services between Mannheim, Germany and Brno, Czechia?

You can take a train from Mannheim, Hauptbahnhof to Brno Hlavni Nadrazi via München Hbf, Muenchen Hbf Gl.5-10, Salzburg Hbf, and Wien Hbf in around 9h 15m. Alternatively, FlixBus operates a bus from Mannheim central bus station to Brno once daily. Tickets cost Kč 1,600–2,400 and the journey takes 10h 15m.

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