There are 10 ways to get from Mannheim to Grenoble by train (TGV), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain 82 / ...
- Take the train from Strasbourg to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Grenobletrain Ter
7h 58m€134–243Bus
cheapest- Take the bus from Mannheim - Bus Station to Lyon - Gerland Bus Stationbus BlaBlaCar Bus
- Take the bus from Lyon to Grenoblebus S1777 / ...
10h 44m€51–93Drive 641.7 km
- Drive from Mannheim to Grenoblecar 641.7 km
6h 11m€103–148Train to Frankfurt, fly to Lyon–Saint Exupéry Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane FRA - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
5h 42m€137–332Train, bus
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Renens VDtrain
- Take the train from Renens VD to Genèvetrain Ic1 / ...
- Take the bus from Geneva - Bus Station to Grenoble - Bus Stationbus
8h 55m€96–218Bus via Freiburg im Breisgau
- Take the bus from Mannheim central bus station to Freiburgbus FlixBus N33 / ...
- Take the bus from Freiburg to Grenoblebus FlixBus N872
12h 11m€55–88Train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport, train
- Take the train from Mannheim, Hauptbahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane SXB - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
5h 27m€147–381Train to Frankfurt, fly to Geneva International Airport, bus, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
- Take the bus from Geneva - Airport Bus Station to Chambéry - Bus Stationbus
- Take the train from Chambery Challes Les Eaux to Grenobletrain
6h 39m€135–323Train to Frankfurt, fly to Turin Caselle Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Turin Caselle Airport (TRN)plane FRA - TRN
- Take the train from Torino Porta Susa to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Grenobletrain
9h 3m€134–384Train, bus to Luxembourg, fly to Geneva International Airport, bus
- Take the train from Mannheim, Hauptbahnhof to Saarbrücken Hbftrain
- Take the bus from Saarbrücken Hbf to Luxembourgbus
- Fly from Luxembourg (LUX) to Geneva International Airport (GVA)plane LUX - GVA
- Take the bus from Geneva - Airport Bus Station to Chambéry - Bus Stationbus
- Take the train from Chambery Challes Les Eaux to Grenobletrain
9h 35m
Mannheim to Grenoble by train
Comparing Your Travel Options
The cheapest way to get from Mannheim to Grenoble is to bus via Freiburg im Breisgau which costs €50 - €90 and takes 12h 11m.
The fastest way to get from Mannheim to Grenoble is to train and fly which takes 5h 27m and costs €140 - €390.
No, there is no direct bus from Mannheim station to Grenoble. However, there are services departing from Mannheim - Bus Station and arriving at Grenoble via Lyon. The journey, including transfers, takes approximately 10h 44m.
No, there is no direct train from Mannheim to Grenoble. However, there are services departing from Mannheim, Hauptbahnhof and arriving at Grenoble via Strasbourg and Lyon Part Dieu. The journey, including transfers, takes approximately 7h 58m.
The distance between Mannheim and Grenoble is 777 km. The road distance is 641.7 km.
The best way to get from Mannheim to Grenoble without a car is to train which takes 7h 58m and costs €130 - €250.
It takes approximately 7h 58m to get from Mannheim to Grenoble, including transfers.
Mannheim to Grenoble bus services, operated by BlaBlaCar Bus, depart from Mannheim - Bus Station.
Mannheim to Grenoble train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Mannheim to Grenoble is to train which takes 7h 58m and costs €130 - €250. Alternatively, you can bus, which costs €50 - €95 and takes 10h 44m.
What companies run services between Mannheim, Germany and Grenoble, France?
You can take a train from Mannheim, Hauptbahnhof to Grenoble via Strasbourg Bahnhof, Strasbourg, and Lyon Part Dieu in around 7h 58m. Alternatively, you can take a bus from Mannheim - Bus Station to Grenoble via Lyon in around 10h 44m.
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €80–490
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €55–340
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- €90–430
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €90–480
Flights from Frankfurt to Turin Caselle Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–460
Flights from Frankfurt to Turin Caselle Airport via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €110–490
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- €90–430
Flights from Frankfurt to Geneva International Airport via Zurich
- Ave. Duration
- 3h 7m
- When
- Monday to Saturday
- Estimated price
- €90–340
Flights from Luxembourg to Geneva International Airport via Zurich
- Ave. Duration
- 2h 52m
- When
- Every day
- Estimated price
- €90–310
- Website
- luxair.lu
Flights from Frankfurt to Turin Caselle Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €110–430
Flights from Luxembourg to Geneva International Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–250
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €150–490
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Sunday
- Estimated price
- €130–430
Flights from Frankfurt to Turin Caselle Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €140–460
- Website
- twinjet.fr
Flights from Strasbourg International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Thursday
- Estimated price
- €600–1,600
- Website
- airfrance.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €55–340
Flights from Luxembourg to Geneva International Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €45–300
- Website
- airbus.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €80–250
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €26–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €45–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 1h 9m
- Frequency
- 4 times a day
- Estimated price
- €26–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €13–27
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €24–50
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 12m
- Frequency
- Every 4 hours
- Estimated price
- €100–150
- Website
- TGV inOui
Train from Lyon Part Dieu to Grenoble
- Ave. Duration
- 1h 11m
- Frequency
- 4 times a week
- Estimated price
- €26–40
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €22–35
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €22–35
- Website
- TGV inOui
Train from Torino Porta Susa to Chambery Challes Les Eaux
- Ave. Duration
- 2h 38m
- Frequency
- Every 4 hours
- Estimated price
- €35–60
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact DetailsContact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Strasbourg to Lyon Part Dieu
- Ave. Duration
- 4h 20m
- Frequency
- Twice daily
- Estimated price
- €85–150
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Grenoble
- Ave. Duration
- 1h 23m
- Frequency
- Every 30 minutes
- Estimated price
- €22–40
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €19–35
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 12m
- Frequency
- Twice daily
- Estimated price
- €19–35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–20
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–20
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Every 20 minutes
- Estimated price
- €11–20
- Website
- Oui.SNCF
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–16
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- €50–80
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Genève
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €17–25
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Renens VD to Genève
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- €8–14
- Website
- Trenitalia Eurocity
- 1st Class
- €8–12
- 2nd Class
- €10–14
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Torino Porta Susa to Chambery Challes Les Eaux
- Ave. Duration
- 2h 35m
- Frequency
- 4 times a day
- Estimated price
- €23–35
- Website
- Trenitalia
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 36m
- Frequency
- Every 2 hours
- Estimated price
- €22–30
- Schedules at
- Süwex
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Mannheim - Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €40–75
- Website
- BlaBlaCar Bus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €7–12
- Website
- BlaBlaCar Bus
Bus from Geneva - Bus Station to Grenoble - Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Every 3 hours
- Estimated price
- €10–17
- Website
- BlaBlaCar Bus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–11
- Website
- BlaBlaCar Bus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–11
- Website
- BlaBlaCar Bus
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mannheim - Bus Station to Lyon - Gerland Bus Station
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €50–80
- Website
- Flixbus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- €8–14
- Website
- Flixbus
Bus from Geneva - Bus Station to Grenoble - Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Hourly
- Estimated price
- €12–19
- Website
- Flixbus
Bus from Mannheim central bus station to Freiburg
- Ave. Duration
- 3h 5m
- Frequency
- Every 4 hours
- Estimated price
- €17–27
- Website
- Flixbus
Bus from Freiburg to Grenoble
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- Flixbus
Bus from Geneva - Airport Bus Station to Chambéry - Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- Flixbus
- Phone
- +352 24 89 24 89
- Website
- Luxembourg Railways (CFL)
Bus from Saarbrücken Hbf to Luxembourg
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- Luxembourg Railways (CFL)
Want to know more about travelling around France
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Train travel in France: A guide to SNCF
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Mannheim to Grenoble bus services, operated by BlaBlaCar Bus, arrive at Lyon - Gerland Bus Station.
Mannheim to Grenoble train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Strasbourg Bahnhof station.
Yes, the driving distance between Mannheim to Grenoble is 642 km. It takes approximately 6h 11m to drive from Mannheim to Grenoble.
Book your Mannheim to Grenoble train tickets online with Omio.
Book your Mannheim to Grenoble bus tickets online with Omio and FlixBus.
There are 2297+ hotels available in Grenoble.










































