There are 10 ways to get from Mannheim to Grenoble by train (TGV), bus, car, train, plane, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mannheim, Hauptbahnhof to Offenburg Bahnhoftrain 12 / ...
- Take the train from Offenburg to Paris Esttrain Tgv
- Take the train from Paris Gare De Lyon to Grenobletrain Tgv
8h 33m€212–355Bus
cheapest- Take the bus from Mannheim central bus station to Lyonbus N7720 / ...
- Take the bus from Lyon to Grenoblebus S1777 / ...
10h 23m€58–95Drive 641.7 km
- Drive from Mannheim to Grenoblecar 641.7 km
6h 11m€121–174Train to Frankfurt, fly to Lyon–Saint Exupéry Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane FRA - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
5h 55m€139–379Train, bus
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Renens VDtrain
- Take the train from Renens VD to Genèvetrain Ic1 / ...
- Take the bus from Geneva - Bus Station to Grenoble - Bus Stationbus
8h 59m€117–224Night train, bus, train
- Take the nighttrain from Mannheim Hbf to Basel Sbbnighttrain Nj
- Take the bus from Basel SBB to Annecybus
- Take the train from Annecy to Grenobletrain K21
11h 1m€79–177Train to Frankfurt, fly to Geneva International Airport, bus, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane FRA - GVA
- Take the bus from Geneva Airport to Chambérybus
- Take the train from Chambery Challes Les Eaux to Grenobletrain
6h 52m€137–330Train, train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport
- Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain
- Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain
- Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane SXB - LYS
- Take the train from Lyon-Saint Exupery Tgv to Grenobletrain
6h 41m€142–396Train to Frankfurt, fly to Turin Caselle Airport, train
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Turin Caselle Airport (TRN)plane FRA - TRN
- Take the train from Torino Porta Susa to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Grenobletrain
9h 18m€140–391Train, bus to Luxembourg, fly to Geneva International Airport, bus
- Take the train from Mannheim, Hauptbahnhof to Saarbrücken Hbftrain
- Take the bus from Saarbrücken Hbf to Luxembourgbus
- Fly from Luxembourg (LUX) to Geneva International Airport (GVA)plane LUX - GVA
- Take the bus from Geneva Airport to Chambérybus
- Take the train from Chambery Challes Les Eaux to Grenobletrain
9h 47m
Mannheim to Grenoble by train and foot
Comparing Your Travel Options
The cheapest way to get from Mannheim to Grenoble is to bus which costs €55 - €95 and takes 10h 23m.
The fastest way to get from Mannheim to Grenoble is to train and fly which takes 5h 55m and costs €130 - €380.
No, there is no direct bus from Mannheim station to Grenoble. However, there are services departing from Mannheim central bus station and arriving at Grenoble via Lyon. The journey, including transfers, takes approximately 10h 23m.
No, there is no direct train from Mannheim to Grenoble. However, there are services departing from Mannheim, Hauptbahnhof and arriving at Grenoble via Offenburg, Paris Nord and Paris Gare De Lyon. The journey, including transfers, takes approximately 8h 33m.
The distance between Mannheim and Grenoble is 1153 km. The road distance is 641.7 km.
The best way to get from Mannheim to Grenoble without a car is to train which takes 8h 33m and costs €210 - €360.
It takes approximately 8h 33m to get from Mannheim to Grenoble, including transfers.
Mannheim to Grenoble bus services, operated by FlixBus, depart from Mannheim central bus station.
Mannheim to Grenoble train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Mannheim to Grenoble is to train which takes 8h 33m and costs €210 - €360. Alternatively, you can bus, which costs €55 - €95 and takes 10h 23m.
What companies run services between Mannheim, Germany and Grenoble, France?
You can take a train from Mannheim, Hauptbahnhof to Grenoble via Offenburg, Paris Est, Paris Nord, and Paris Gare De Lyon in around 8h 33m. Alternatively, you can take a bus from Mannheim central bus station to Grenoble via Lyon in around 10h 23m.
- Website
- lufthansa.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–500
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Munich
- Ave. Duration
- 3h 40m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €80–240
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €100–440
Flights from Frankfurt to Geneva International Airport via Munich
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €100–230
Flights from Frankfurt to Turin Caselle Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €150–450
Flights from Frankfurt to Turin Caselle Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–470
- Website
- swiss.com
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- €100–440
Flights from Frankfurt to Geneva International Airport via Zurich
- Ave. Duration
- 2h 53m
- When
- Every day
- Estimated price
- €100–440
Flights from Luxembourg to Geneva International Airport via Zurich
- Ave. Duration
- 2h 51m
- When
- Every day
- Estimated price
- €90–310
- Website
- airbus.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €75–230
- Website
- airdolomiti.it
Flights from Frankfurt to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 20m
- When
- Monday to Saturday
- Estimated price
- €170–500
Flights from Frankfurt to Geneva International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €150–440
Flights from Frankfurt to Turin Caselle Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €150–450
- Website
- luxair.lu
Flights from Luxembourg to Geneva International Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–250
- Website
- brusselsairlines.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €75–280
Flights from Frankfurt to Geneva International Airport via Brussels
- Ave. Duration
- 3h 20m
- When
- Every day
- Estimated price
- €150–300
- Website
- twinjet.fr
Flights from Strasbourg International Airport to Lyon–Saint Exupéry Airport
- Ave. Duration
- 1h 10m
- When
- Monday to Friday
- Estimated price
- €650–1,300
- Website
- airfrance.com
Flights from Frankfurt to Lyon–Saint Exupéry Airport via Paris Charles de Gaulle
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €55–330
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–90
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 22 min
- Frequency
- Hourly
- Estimated price
- €9–21
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhof
- Ave. Duration
- 43 min
- Frequency
- Every 3 hours
- Estimated price
- €13–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €11–25
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 19m
- Frequency
- Every 4 hours
- Estimated price
- €21–45
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 1h 24m
- Frequency
- Once daily
- Estimated price
- €33
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 42 min
- Frequency
- Once daily
- Estimated price
- €16
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 6131 4975 022
- [email protected]
- Website
- dbregiobus-mitte.de
Train from Mannheim, Hauptbahnhof to Offenburg Bahnhof
- Ave. Duration
- 3h 2m
- Frequency
- Once a week
- Estimated price
- €28–40
- Schedules at
- dbregiobus-mitte.de
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once a week
- Estimated price
- €13–19
- Schedules at
- dbregiobus-mitte.de
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Offenburg to Paris Est
- Ave. Duration
- 2h 19m
- Frequency
- Once daily
- Estimated price
- €90–140
- Website
- TGV inOui
Train from Paris Gare De Lyon to Grenoble
- Ave. Duration
- 3h
- Frequency
- Every 4 hours
- Estimated price
- €110–170
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Website
- TGV inOui
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- €23–35
- Website
- TGV inOui
Train from Torino Porta Susa to Chambery Challes Les Eaux
- Ave. Duration
- 2h 34m
- Frequency
- 3 times a day
- Estimated price
- €35–60
- Website
- TGV inOui
Rome2Rio's guide to Société Nationale des Chemins de fer Français (SNCF)
Contact Details
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Paris Gare De Lyon to Grenoble
- Ave. Duration
- 3h 6m
- Frequency
- Once daily
- Estimated price
- €100–170
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €21–35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €12–20
- Website
- Oui.SNCF
Train from Lyon-Saint Exupery Tgv to Grenoble
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €21–35
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €12–20
- Website
- Oui.SNCF
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €12–20
- Website
- Oui.SNCF
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mannheim Hbf to Basel Sbb
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Renens VD
- Ave. Duration
- 2h 16m
- Frequency
- Hourly
- Estimated price
- €55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Renens VD to Genève
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €18–29
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Renens VD to Genève
- Ave. Duration
- 44 min
- Frequency
- 5 times a week
- Estimated price
- €8–14
- Website
- Trenitalia Eurocity
- 1st Class
- €8–12
- 2nd Class
- €10–14
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mannheim Hbf to Basel Sbb
- Ave. Duration
- 2h 47m
- Frequency
- Once daily
- Estimated price
- €23–95
- Website
- Nightjet
- Sleeper Carriage
- €85–95
- Couchette Carriage
- €55–65
- Seating Carriage
- €23–28
- Phone
- +33 4 13 94 30 50
- Website
- Zou! Lignes Express Régionales
Train from Annecy to Grenoble
- Ave. Duration
- 1h 44m
- Frequency
- Every 2 hours
- Estimated price
- €30–45
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
Train from Chambery Challes Les Eaux to Grenoble
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- Zou! Lignes Express Régionales
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 57 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–10
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 621 830 1200
- Website
- Süwex
Train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhof
- Ave. Duration
- 1h 6m
- Frequency
- 5 times a week
- Estimated price
- €13–19
- Schedules at
- Süwex
Train from Mannheim, Hauptbahnhof to Saarbrücken Hbf
- Ave. Duration
- 1h 36m
- Frequency
- Every 2 hours
- Estimated price
- €22–30
- Schedules at
- Süwex
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Torino Porta Susa to Chambery Challes Les Eaux
- Ave. Duration
- 2h 35m
- Frequency
- Twice daily
- Estimated price
- €23–35
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mannheim central bus station to Lyon
- Ave. Duration
- 8h 50m
- Frequency
- 3 times a day
- Estimated price
- €55–85
- Website
- Flixbus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €9–14
- Website
- Flixbus
Bus from Geneva - Bus Station to Grenoble - Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 2 hours
- Estimated price
- €13–20
- Website
- Flixbus
Bus from Basel SBB to Annecy
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- €26–40
- Website
- Flixbus
Bus from Geneva Airport to Chambéry
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €8–12
- Website
- Flixbus
Bus from Geneva Airport to Chambéry
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- €8–12
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Mannheim central bus station to Lyon
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €50–80
- Website
- BlaBlaCar Bus
Bus from Lyon to Grenoble
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- BlaBlaCar Bus
Bus from Geneva - Bus Station to Grenoble - Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Every 2 hours
- Estimated price
- €12–20
- Website
- BlaBlaCar Bus
Bus from Geneva Airport to Chambéry
- Ave. Duration
- 1h 30m
- Frequency
- Every 2 hours
- Estimated price
- €7–12
- Website
- BlaBlaCar Bus
Bus from Geneva Airport to Chambéry
- Ave. Duration
- 1h 30m
- Frequency
- Every 2 hours
- Estimated price
- €7–12
- Website
- BlaBlaCar Bus
- Phone
- +352 24 89 24 89
- Website
- Luxembourg Railways (CFL)
Bus from Saarbrücken Hbf to Luxembourg
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- Luxembourg Railways (CFL)
Want to know more about travelling around France
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Booking & Getting There
Mannheim to Grenoble bus services, operated by FlixBus, arrive at Lyon station.
Mannheim to Grenoble train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Offenburg Bahnhof station.
Yes, the driving distance between Mannheim to Grenoble is 642 km. It takes approximately 6h 11m to drive from Mannheim to Grenoble.
Book your Mannheim to Grenoble train tickets online with Omio.
Book your Mannheim to Grenoble bus tickets online with Omio, FlixBus and 12go.asia.
There are 2323+ hotels available in Grenoble.
























































