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How to get fromMannheim to Grenobleby train (TGV), bus, car, train, or plane

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There are 9 ways to get from Mannheim to Grenoble by train (TGV), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train 12 / ...
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Grenobletrain train Ter
    8h 54m
    €140–245

  2. Bus

    cheapest
    1. Take the bus from Mannheim - Bus Station to Lyon - Gerland Bus Stationbus bus BlaBlaCar Bus
    2. Take the bus from Lyon to Grenoblebus bus S1777 / ...
    10h 38m
    €59–97

  3. Drive  641.7 km

    1. Drive from Mannheim to Grenoblecar car 641.7 km
    6h 11m
    €122–176

  4. Train to Frankfurt, fly to Lyon–Saint Exupéry Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    3. Take the train from Lyon-Saint Exupery Tgv to Grenobletrain train
    5h 41m
    €140–377

  5. Train, bus

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Renens VDtrain train
    3. Take the train from Renens VD to Genèvetrain train Ic1 / ...
    4. Take the bus from Geneva - Bus Station to Annecy - Bus Stationbus bus
    5. Take the train from Annecy to Grenobletrain train Ter
    9h 25m
    €130–244

  6. Bus via Freiburg im Breisgau

    1. Take the bus from Mannheim central bus station to Freiburgbus bus FlixBus N1720 / ...
    2. Take the bus from Freiburg to Grenoblebus bus FlixBus N872
    13h 35m
    €63–98

  7. Train to Frankfurt, fly to Geneva International Airport, bus, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Geneva International Airport (GVA)plane plane FRA - GVA
    3. Take the bus from Geneva - Airport Bus Station to Annecy - Bus Stationbus bus
    4. Take the train from Annecy to Grenobletrain train
    7h 6m
    €144–342

  8. Train, train to Strasbourg International Airport, fly to Lyon–Saint Exupéry Airport

    1. Take the train from Mannheim, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train
    3. Fly from Strasbourg International Airport (SXB) to Lyon–Saint Exupéry Airport (LYS)plane plane SXB - LYS
    4. Take the train from Lyon-Saint Exupery Tgv to Grenobletrain train
    6h 22m
    €143–403

  9. Train to Frankfurt, fly to Turin Caselle Airport, train

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Turin Caselle Airport (TRN)plane plane FRA - TRN
    3. Take the train from Torino Porta Susa to Chambery Challes Les Eauxtrain train
    4. Take the train from Chambery Challes Les Eaux to Grenobletrain train
    9h 6m
    €141–389

Mannheim to Grenoble by train

Calendar63Weekly Trains
Duration8h 54mAverage Duration
Ticket€140Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mannheim to Grenoble.ExpandLaunch map view
  • Distance: 777.3 km
  • Duration: 8h 54m

What companies run services between Mannheim, Germany and Grenoble, France?

You can take a train from Mannheim, Hauptbahnhof to Grenoble via Karlsruhe Hauptbahnhof, Strasbourg Bahnhof, Strasbourg, and Lyon Part Dieu in around 8h 54m. Alternatively, you can take a bus from Mannheim - Bus Station to Grenoble via Lyon in around 10h 38m.

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