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How to get fromMannheim to Palermoby train, plane, train (Trenitalia), car, car ferry, or bus

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There are 7 ways to get from Mannheim to Palermo by train, plane, train (Trenitalia), car, car ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 44m
    €81–257

  2. Train

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Roma Terminitrain train
    5. Take the train from Roma Termini to Palermo Centraletrain train Ic
    23h 58m
    €245–869

  3. Drive, car ferry

    1. Drive from Mannheim to Port of Genoacar car
    2. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    27h 57m
    €215–326

  4. Bus via Rome

    1. Take the bus from Mannheim central bus station to Roma, Autostazione Tiburtinabus bus N77
    2. Take the bus from Roma, Autostazione Tiburtina to Palermobus bus N592
    33h 45m
    €169–270

  5. Train to Stuttgart Airport, fly

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane plane STR - PMO
    6h 11m
    €94–328

  6. Train via Zurich

    1. Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain train 12 / ...
    2. Take the train from Basel SBB to Zürich HBtrain train Tgv / ...
    3. Take the train from Zürich HB to Como S. Giovannitrain train Ec
    4. Take the train from Como S.Giovanni to Rhotrain train S11
    5. Take the train from RHO Fiera to Roma Terminitrain train
    6. Take the train from Roma Termini to Palermo Centraletrain train Ic
    27h 5m
    €303–894

  7. Bus

    1. Take the bus from Mannheim, Zob to Palermo Piazza Cairolibus bus
    35h 51m
    €280–390

Mannheim to Palermo by train

Calendar25Weekly Trains
Duration23h 58mAverage Duration
Ticket€245Cheapest Price
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Questions & Answers

Map of how to get from Mannheim to Palermo.ExpandLaunch map view
  • Distance: 1,470.3 km
  • Duration: 5h 44m

What companies run services between Mannheim, Germany and Palermo, Italy?

You can take a train from Mannheim, Hauptbahnhof to Palermo Centrale via Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 23h 58m. Alternatively, you can take a bus from Mannheim central bus station to Palermo via Roma, Autostazione Tiburtina in around 33h 45m.

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