There are 12 ways to get from Mannheim to Palermo by train, plane, train (Trenitalia), car, car ferry, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Frankfurt, fly to Palermo Airport
best- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
5h 53m€91–252Train, train to Allgäu Airport, Memmingen, fly to Palermo Airport
cheapest- Take the train from Mannheim, Hauptbahnhof to Ulm Hauptbahnhoftrain
- Take the train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOBtrain
- Fly from Allgäu Airport, Memmingen (FMM) to Palermo Airport (PMO)plane FMM - PMO
8h 5m€74–360Train
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
23h 57m€231–581Drive, car ferry
- Drive from Mannheim to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
27h 57m€218–321Bus via Rome
- Take the bus from Mannheim central bus station to Roma, Autostazione Tiburtinabus N77
- Take the bus from Roma, Autostazione Tiburtina to Palermobus N592
33h 45m€195–292Train to Stuttgart Airport, fly to Palermo Airport
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane STR - PMO
6h 20m€88–320Train to Cologne Bonn Airport, fly to Palermo Airport
- Take the train from Mannheim, Hauptbahnhof to Köln Hbftrain
- Fly from Cologne Bonn Airport (CGN) to Palermo Airport (PMO)plane CGN - PMO
7h 19m€111–428Train to Frankfurt, fly to Catania–Fontanarossa Airport, bus
- Take the train from Mannheim, Hauptbahnhof to Frankfurttrain
- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
8h 26m€99–274Train, train to Zurich Airport, fly to Palermo Airport
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain
- Take the train from Basel SBB to Zürich HBtrain
- Fly from Zurich Airport (ZRH) to Palermo Airport (PMO)plane ZRH - PMO
8h 47m€144–355Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane STR - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
8h 58m€96–322Train, car ferry
- Take the train from Mannheim, Hauptbahnhof to Basel SBBtrain 12 / ...
- Take the train from Basel SBB to Arth-Goldautrain Ec
- Take the train from Arth-Goldau to Chiassotrain Ec / ...
- Take the train from Chiasso to Genova P. Principetrain Ec
- Take the carferry from Port of Genoa to Port of Palermocarferry
32h 38m€219–521Bus
- Take the bus from Mannheim, Zob to Palermo Piazza Cairolibus
35h 41m€280–390
Mannheim to Palermo by train
Comparing Your Travel Options
The cheapest way to get from Mannheim to Palermo is to train and fly which costs €70 - €360 and takes 8h 5m.
The fastest way to get from Mannheim to Palermo is to train and fly which takes 5h 53m and costs €90 - €260.
Yes, there is a direct bus departing from Mannheim, Zob and arriving at Palermo Piazza Cairoli. Services depart once a week, and operate Wednesday and Saturday. The journey takes approximately 35h 41m.
No, there is no direct train from Mannheim to Palermo. However, there are services departing from Mannheim, Hauptbahnhof and arriving at Palermo Centrale via Basel SBB, Lugano, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 23h 57m.
The distance between Mannheim and Palermo is 1470 km.
The best way to get from Mannheim to Palermo without a car is to train which takes 23h 57m and costs €230 - €600.
It takes approximately 5h 53m to get from Mannheim to Palermo, including transfers.
Mannheim to Palermo bus services, operated by FlixBus, depart from Mannheim central bus station.
Mannheim to Palermo train services, operated by Deutsche Bahn Intercity (DB IC), depart from Mannheim, Hauptbahnhof station.
The best way to get from Mannheim to Palermo is to train which takes 23h 57m and costs €230 - €600. Alternatively, you can bus via Rome, which costs €190 - €300 and takes 33h 45m.
What companies run services between Mannheim, Germany and Palermo, Italy?
You can take a train from Mannheim, Hauptbahnhof to Palermo Centrale via Basel SBB, Lugano, Milano Centrale, and Roma Termini in around 23h 57m. Alternatively, you can take a bus from Mannheim central bus station to Palermo via Roma, Autostazione Tiburtina in around 33h 45m.
- Website
- ita-airways.com
Flights from Stuttgart Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 23m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–260
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €75–270
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- €65–210
Flights from Zurich Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- €60–250
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 46m
- When
- Sunday to Friday
- Estimated price
- €65–220
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich Airport
- Ave. Duration
- 4h 35m
- When
- Sunday, Monday, Wednesday, Tuesday, Friday, and Saturday
- Estimated price
- €65–270
Flights from Cologne Bonn Airport to Palermo Airport via Zurich Airport
- Ave. Duration
- 5h 10m
- When
- Monday and Wednesday
- Estimated price
- €70–280
Flights from Frankfurt to Catania–Fontanarossa Airport via Zurich Airport
- Ave. Duration
- 5h 5m
- When
- Monday, Wednesday, Thursday, and Sunday
- Estimated price
- €55–280
Flights from Zurich Airport to Palermo Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- €60–250
Flights from Zurich Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- €60–250
- Website
- lufthansa.com
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Thursday to Sunday
- Estimated price
- €80–290
Flights from Stuttgart Airport to Palermo Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Thursday, and Sunday
- Estimated price
- €90–320
Flights from Cologne Bonn Airport to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Monday, Tuesday, Thursday, and Friday
- Estimated price
- €85–310
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €75–270
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €60–310
- Website
- eurowings.com
Flights from Stuttgart Airport to Palermo Airport
- Ave. Duration
- 2h 5m
- When
- Sunday
- Estimated price
- €65–260
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Saturday
- Estimated price
- €120–310
Flights from Stuttgart Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Saturday to Thursday
- Estimated price
- €65–220
- Website
- ryanair.com
Flights from Cologne Bonn Airport to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Thursday, Friday, and Saturday
- Estimated price
- €45–180
Flights from Cologne Bonn Airport to Palermo Airport via Bologna
- Ave. Duration
- 5h
- When
- Friday
- Estimated price
- €45–180
Flights from Allgäu Airport, Memmingen to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €40–210
- Website
- lufthansa-city.com
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Wednesday, Thursday, and Sunday
- Estimated price
- €60–310
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €18–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Köln Hbf
- Ave. Duration
- 1h 31m
- Frequency
- Hourly
- Estimated price
- €40–95
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Hourly
- Estimated price
- €12–28
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Ulm Hauptbahnhof
- Ave. Duration
- 1h 27m
- Frequency
- Hourly
- Estimated price
- €30–75
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOB
- Ave. Duration
- 28 min
- Frequency
- Once daily
- Estimated price
- €9–20
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €18–45
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €40–100
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €11–23
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Frankfurt
- Ave. Duration
- 31 min
- Frequency
- Once daily
- Estimated price
- €7–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Ulm Hauptbahnhof
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- €21–45
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- 3 times a day
- Estimated price
- €11–23
- Website
- Nederlandse Spoorwegen (NS)
Train from Mannheim, Hauptbahnhof to Basel SBB
- Ave. Duration
- 2h 50m
- Frequency
- Once daily
- Estimated price
- €27–55
- Website
- Nederlandse Spoorwegen (NS)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €90–150
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €28–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Zürich HB
- Ave. Duration
- 1h 13m
- Frequency
- Every 20 minutes
- Estimated price
- €30–55
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Basel SBB to Arth-Goldau
- Ave. Duration
- 1h 41m
- Frequency
- Every 3 hours
- Estimated price
- €40–70
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Arth-Goldau to Chiasso
- Ave. Duration
- 1h 37m
- Frequency
- Hourly
- Estimated price
- €55–95
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Chiasso to Genova P. Principe
- Ave. Duration
- 2h 50m
- Frequency
- Twice a week
- Estimated price
- €70–110
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
Train from Basel SBB to Arth-Goldau
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- €10–14
- Schedules at
- SBB GmbH
Train from Arth-Goldau to Chiasso
- Ave. Duration
- 1h 37m
- Frequency
- Once daily
- Estimated price
- €11–14
- Schedules at
- SBB GmbH
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Ulm Hauptbahnhof to Memmingen, Bahnhof ZOB
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €9–40
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Basel SBB to Arth-Goldau
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €35–60
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mannheim central bus station to Roma, Autostazione Tiburtina
- Ave. Duration
- 18h 50m
- Frequency
- Once daily
- Estimated price
- €110–170
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 55m
- Frequency
- 5 times a week
- Estimated price
- €85–130
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €18–27
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €18–27
- Website
- Flixbus
- Phone
- 800 21 10 20
- [email protected]
- Website
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Mannheim, Zob to Palermo Piazza Cairoli
- Ave. Duration
- 35h 41m
- Frequency
- Once a week
- Estimated price
- €280–390
- Website
- Onebus
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 20h 45m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
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Booking & Getting There
Mannheim to Palermo bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Mannheim to Palermo train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Book your Mannheim to Palermo train tickets online with Omio.
Book your Mannheim to Palermo bus tickets online with Omio and FlixBus.
There are 6119+ hotels available in Palermo.





















































