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How to get fromMannheim to Pilsenby train, bus, car, or plane

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There are 7 ways to get from Mannheim to Pilsen by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Nuremberg

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    3. Take the bus from Nürnberg to Plzeň,Terminál Hlavní nádražíbus bus
    6h 21m
    Kč 1,890–5,883

  2. Bus

    cheapest
    1. Take the bus from Mannheim central bus station to Frankfurt central train stationbus bus FlixBus 108 / ...
    2. Take the bus from Frankfurt Central Train Station to Pilsen Central Bus Stationbus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    7h 15m
    Kč 863–1,413

  3. Train, bus

    1. Take the train from Mannheim, Hauptbahnhof to Heilbronn Hauptbahnhoftrain train RE10b / ...
    2. Take the bus from Heilbronn central train station to Plzeňbus bus N1315 / ...
    7h 9m
    Kč 1,070–1,821

  4. Drive  419.1 km

    1. Drive from Mannheim to Pilsencar car 419.1 km
    3h 34m
    Kč 1,575–2,275

  5. Train, fly, bus

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    3. Take the bus from Prague to Plzeňbus bus
    5h 36m
    Kč 1,656–4,093

  6. Train via Nuremberg

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 20 / ...
    2. Take the train from Frankfurt to Nürnberg Hbftrain train 41 / ...
    3. Take the train from Nürnberg Hbf to Schwandorftrain train
    4. Take the train from Schwandorf to Plzen Hlavni Nadrazitrain train Re
    7h 40m
    Kč 2,740–8,133

  7. Train

    1. Take the train from Mannheim, Hauptbahnhof to München Hbftrain train 11 / ...
    2. Take the train from Muenchen Hbf to Plzen Hlavni Nadrazitrain train Re
    7h 45m
    Kč 3,035–10,576

Mannheim to Pilsen by train and bus

Calendar9Weekly Services
Duration7h 9mAverage Duration
TicketKč 1,070Cheapest Price
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Questions & Answers

Map of how to get from Mannheim to Pilsen.ExpandLaunch map view
  • Distance: 500.1 km
  • Duration: 6h 21m

What companies run services between Mannheim, Germany and Pilsen, Czechia?

You can take a bus from Mannheim central bus station to Pilsen Central Bus Station via Frankfurt Central Train Station in around 7h 15m. Alternatively, you can take a train from Mannheim, Hauptbahnhof to Plzen Hlavni Nadrazi via Frankfurt, Nürnberg Hbf, and Schwandorf in around 7h 40m.

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