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How to get fromMannheim to Sicilyby train, plane, bus, car, car ferry, or night train

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There are 9 ways to get from Mannheim to Sicily by train, plane, bus, car, car ferry, or night train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Frankfurt, fly to Catania–Fontanarossa Airport

    best
    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    5h 23m
    €87–250

  2. Train, bus

    1. Take the train from Mannheim, Hauptbahnhof to Heilbronn Hauptbahnhoftrain train
    2. Take the bus from Heilbronn ZOB - Fernbusbahnhof - Bahnhofstrasse 41 to Verona Porta Nuova Stationbus bus
    3. Take the train from Verona Porta Nuova to Roma Terminitrain train Fr
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    25h 52m
    €240–456

  3. Drive, car ferry

    1. Drive from Mannheim to Port of Genoacar car
    2. Take the carferry from Port of Genoa to Port of Palermocarferry car ferry
    28h 4m
    €219–321

  4. Bus via Rome

    1. Take the bus from Mannheim central bus station to Roma, Autostazione Tiburtinabus bus N77
    2. Take the bus from Roma, Autostazione Tiburtina to Palermobus bus N592
    34h 16m
    €185–287

  5. Train to Frankfurt, fly to Palermo Airport

    1. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    5h 44m
    €91–241

  6. Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    5h 50m
    €89–297

  7. Train to Stuttgart Airport, fly to Palermo Airport

    1. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Palermo Airport (PMO)plane plane STR - PMO
    6h 11m
    €88–308

  8. Train, night train

    1. Take the train from Mannheim, Hauptbahnhof to Augsburg Hbftrain train 11 / ...
    2. Take the nighttrain from Augsburg Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Roma Terminitrain train
    4. Take the train from Roma Termini to Palermo Centraletrain train Ic
    30h 8m
    €217–495

  9. Bus

    1. Take the bus from Mannheim, Zob to Palermo Piazza Cairolibus bus
    36h 7m
    €287–388

Mannheim to Sicily by bus

Calendar7Weekly Buses
Duration34h 16mAverage Duration
Ticket€185Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mannheim to Sicily.ExpandLaunch map view
  • Distance: 1,567.5 km
  • Duration: 5h 23m

What companies run services between Mannheim, Germany and Sicily, Italy?

You can take a bus from Mannheim central bus station to Piazza Boiardo via Roma, Autostazione Tiburtina, Palermo, and Stazione Centrale Pensilina Esterna in around 34h 16m.

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