There are 9 ways to get from Mantua to Isernia by train (Trenitalia), bus, car, train, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Mantova to Roma Terminitrain Fr
- Take the train from Roma Termini to Iserniatrain Re
6h 53m€88–170Bus
cheapest- Take the bus from Mantua to Roma, Autostazione Tiburtinabus N532 / ...
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
9h 10m€43–77Drive 622.8 km
- Drive from Mantua to Iserniacar 622.8 km
5h 47m€99–142Train to Bologna Guglielmo Marconi Airport, fly to Fiumicino International Airport, train
- Take the train from Mantova to Bologna Centraletrain
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Fiumicino International Airport (FCO)plane BLQ - FCO
- Take the train from Roma Termini to Iserniatrain
7h 6m€85–255Bus, train
- Take the bus from Mincio to Poggio Ruscobus 35
- Take the train from Poggio Rusco to Bologna Centraletrain Re
- Take the train from Bologna centrale to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
8h 27m€79–142Shuttle to Milan Linate Airport, fly to Naples Airport, train
- Take a shuttle bus from Mantova to Milano Linate airport
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Caserta to Iserniatrain
8h 51m€242–677Fly Verona Villafranca Airport to Naples Airport, train
- Fly from Verona Villafranca Airport (VRN) to Naples Airport (NAP)plane VRN - NAP
- Take the train from Caserta to Iserniatrain
7h 22m€63–246Train to Venice Marco Polo Airport, fly to Naples Airport, train
- Take the train from Verona Porta Nuova to Venezia Mestretrain
- Fly from Venice Marco Polo Airport (VCE) to Naples Airport (NAP)plane VCE - NAP
- Take the train from Caserta to Iserniatrain
8h 32m€47–246Bus to Il Caravaggio International Airport, fly to Naples Airport, train
- Take the bus from Verona to Bergamobus
- Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane BGY - NAP
- Take the train from Caserta to Iserniatrain
8h 48m€60–243
Mantua to Isernia by train (Trenitalia)
Questions & Answers
The cheapest way to get from Mantua to Isernia is to bus which costs €40 - €80 and takes 9h 10m.
The fastest way to get from Mantua to Isernia is to drive which takes 5h 47m and costs €95 - €150.
No, there is no direct bus from Mantua to Isernia. However, there are services departing from Mantua and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 9h 10m.
No, there is no direct train from Mantua to Isernia. However, there are services departing from Mantova and arriving at Isernia via Roma Termini. The journey, including transfers, takes approximately 6h 53m.
The distance between Mantua and Isernia is 636 km. The road distance is 622.8 km.
The best way to get from Mantua to Isernia without a car is to train which takes 6h 53m and costs €85 - €170.
It takes approximately 6h 53m to get from Mantua to Isernia, including transfers.
Mantua to Isernia bus services, operated by FlixBus, depart from Mantua station.
Mantua to Isernia train services, operated by Trenitalia Frecce, depart from Mantova station.
The best way to get from Mantua to Isernia is to train which takes 6h 53m and costs €85 - €170. Alternatively, you can bus, which costs €40 - €80 and takes 9h 10m.
What companies run services between Mantua, Italy and Isernia, Italy?
You can take a train from Mantova to Isernia via Roma Termini in around 6h 53m. Alternatively, you can take a bus from Mantua to Isernia via Roma, Autostazione Tiburtina in around 9h 10m.
- Website
- ryanair.com
Flights from Verona Villafranca Airport to Naples Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Tuesday, Friday, and Saturday
- Estimated price
- €40–180
Flights from Venice Marco Polo Airport to Naples Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €29–140
Flights from Il Caravaggio International Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €35–190
Flights from Il Caravaggio International Airport to Naples Airport via Palermo
- Ave. Duration
- 3h 40m
- When
- Tuesday
- Estimated price
- €35–190
- Phone
- +39 06 68475475
- Website
- Trenitalia Frecce
Train from Mantova to Roma Termini
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €65–130
- Schedules at
- Trenitalia Frecce
Train from Mantova to Bologna Centrale
- Ave. Duration
- 1h 9m
- Frequency
- Twice daily
- Estimated price
- €14–29
- Schedules at
- Trenitalia Frecce
Train from Verona Porta Nuova to Venezia Mestre
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €16–35
- Schedules at
- Trenitalia Frecce
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Mantua to Roma, Autostazione Tiburtina
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €35–60
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €13–21
- Website
- Flixbus
Bus from Verona to Bergamo
- Ave. Duration
- 1h 20m
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- Flixbus
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More Questions & Answers
Mantua to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Mantua to Isernia train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
Yes, the driving distance between Mantua to Isernia is 623 km. It takes approximately 5h 47m to drive from Mantua to Isernia.
Book your Mantua to Isernia train tickets online with Omio.
Book your Mantua to Isernia bus tickets online with Omio and FlixBus.
There are 466+ hotels available in Isernia.







