There are 6 ways to get from Manzanillo to Panama City by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Playa De Oro International Airport
best- Fly from Playa De Oro International Airport (ZLO) to Tocumen International Airport (PTY)plane ZLO - PTY
7h 54m$298–1,086Bus to Licenciado Miguel De La Madrid Airport, fly
cheapest- Take the bus from Manzanillo to Colimabus
- Fly from Licenciado Miguel De La Madrid Airport (CLQ) to Tocumen International Airport (PTY)plane CLQ - PTY
19h 2m$265–1,019Bus
- Take the bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1 1/2bus
- Take the bus from Guadalajara to Los Angelesbus
- Take the bus from Los Angeles to San Salvadorbus
- Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus
- Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus
7d 11h$587–780Drive 3,896.5 km
- Drive from Manzanillo to Panama Citycar 3,896.5 km
2d 5h$533–770Bus to Miguel Hidalgo Y Costilla Guadalajara International Airport, fly
- Take the bus from Manzanillo to Guadalajara Airportbus
- Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Tocumen International Airport (PTY)plane GDL - PTY
11h 26m$572–1,511Bus to Licenciado Gustavo Díaz Ordaz International Airport, fly
- Take the bus from Manzanillo to Puerto Vallartabus
- Fly from Licenciado Gustavo Díaz Ordaz International Airport (PVR) to Tocumen International Airport (PTY)plane PVR - PTY
13h 50m$430–1,570
Playa De Oro International Airport (ZLO) to Tocumen International Airport (PTY) flights
Questions & Answers
The cheapest way to get from Manzanillo to Panama City is to bus and fly which costs $260 - $1,100 and takes 19h 2m.
The fastest way to get from Manzanillo to Panama City is to fly which takes 7h 54m and costs $290 - $1,100.
No, there is no direct bus from Manzanillo to Panama City. However, there are services departing from Parada en Av. Elias Zamora Verduzco and arriving at Terminal Tica Bus Panamá via Manzanillo, Guadalajara, Los Angeles, Terminal Tica Bus San Salvador and Terminal Tica Bus San José. The journey, including transfers, takes approximately 7 days 11h.
The distance between Manzanillo and Panama City is 2987 km. The road distance is 3896.5 km.
The best way to get from Manzanillo to Panama City without a car is to bus which takes 7 days 11h and costs $550 - $800.
It takes approximately 7h 54m to get from Manzanillo to Panama City, including transfers.
Manzanillo to Panama City bus services, operated by Autocamiones del Pacifico, depart from Manzanillo station.
The best way to get from Manzanillo to Panama City is to fly which takes 7h 54m and costs $290 - $1,100. Alternatively, you can bus, which costs $550 - $800 and takes 7 days 11h.
Manzanillo to Panama City bus services, operated by Autocamiones del Pacifico, arrive at Nueva Central Camionera de Guadalajara Mod 1 1/2 station.
Panama City is 1h ahead of Manzanillo. It is currently 2:02 PM in Manzanillo and 3:02 PM in Panama City.
What companies run services between Manzanillo, Mexico and Panama City, Panama?
Aeroméxico and Copa Airlines fly from Playa De Oro International Airport (ZLO) to Tocumen International Airport (PTY) 4 times a day. Alternatively, you can take a bus from Parada en Av. Elias Zamora Verduzco to Terminal Tica Bus Panamá via Parada en Obras Maritimas 42, Manzanillo, Nueva Central Camionera de Guadalajara Mod 1 1/2, Guadalajara, Los Angeles, San Salvador, Terminal Tica Bus San Salvador, and Terminal Tica Bus San José in around 7d 11h.
- Website
- copaair.com
Flights from Playa De Oro International Airport to Tocumen International Airport via Mexico City
- Ave. Duration
- 9h 41m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Miguel Hidalgo Y Costilla Guadalajara International Airport to Tocumen International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–450
Flights from Licenciado Miguel De La Madrid Airport to Tocumen International Airport via Mexico City
- Ave. Duration
- 13h 33m
- When
- Every day
- Estimated price
- $210–950
Flights from Licenciado Gustavo Díaz Ordaz International Airport to Tocumen International Airport via Miguel Hidalgo Y Costilla Guadalajara International Airport
- Ave. Duration
- 6h 15m
- When
- Thursday to Sunday
- Estimated price
- $130–600
Flights from Licenciado Gustavo Díaz Ordaz International Airport to Tocumen International Airport via Mexico City
- Ave. Duration
- 8h 40m
- When
- Every day
- Estimated price
- $130–600
Flights from Licenciado Gustavo Díaz Ordaz International Airport to Tocumen International Airport via Monterrey
- Ave. Duration
- 9h 33m
- When
- Every day
- Estimated price
- $150–650
- Phone
- +52 33 3600 0598
- [email protected]
- Website
- Autocamiones del Pacifico
Bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1 1/2
- Ave. Duration
- 4h
- Frequency
- Every 4 hours
- Estimated price
- $22–35
- Schedules at
- Autocamiones del Pacifico
Bus from Manzanillo to Puerto Vallarta
- Ave. Duration
- 3h 30m
- Frequency
- Every 4 hours
- Estimated price
- $21–30
- Schedules at
- Autocamiones del Pacifico
Want to know more about travelling around Panama
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More Questions & Answers
Yes, the driving distance between Manzanillo to Panama City is 3897 km. It takes approximately 2 days 5h to drive from Manzanillo to Panama City.
There are 864+ hotels available in Panama City.


