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How to get fromManzanillo to Panama Cityby bus, plane, or car

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There are 6 ways to get from Manzanillo to Panama City by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Miguel Hidalgo Y Costilla Guadalajara International Airport, fly

    best
    1. Take the bus from Manzanillo to Guadalajara Airportbus bus
    2. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Tocumen International Airport (PTY)plane plane GDL - PTY
    11h 26m
    $171–559

  2. Bus

    1. Take the bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1 1/2bus bus
    2. Take the bus from Guadalajara to Los Angelesbus bus
    3. Take the bus from Los Angeles to San Salvadorbus bus
    4. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    7d 11h
    $587–775

  3. Drive  3,896.5 km

    1. Drive from Manzanillo to Panama Citycar car 3,896.5 km
    2d 5h
    $533–770

  4. Fly from Playa De Oro International Airport

    1. Fly from Playa De Oro International Airport (ZLO) to Tocumen International Airport (PTY)plane plane ZLO - PTY
    8h 6m
    $287–1,034

  5. Bus to Licenciado Miguel De La Madrid Airport, fly

    1. Take the bus from Manzanillo to Colimabus bus
    2. Fly from Licenciado Miguel De La Madrid Airport (CLQ) to Tocumen International Airport (PTY)plane plane CLQ - PTY
    18h 47m
    $255–969

  6. Bus to Licenciado Gustavo Díaz Ordaz International Airport, fly

    1. Take the bus from Manzanillo to Puerto Vallartabus bus
    2. Fly from Licenciado Gustavo Díaz Ordaz International Airport (PVR) to Tocumen International Airport (PTY)plane plane PVR - PTY
    13h 44m
    $430–1,569

Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Tocumen International Airport (PTY) flights

Calendar21Weekly Planes
Duration5h 29mAverage Duration
Ticket$101Cheapest Price
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Comparing Your Travel Options

Map of how to get from Manzanillo to Panama City.ExpandLaunch map view
  • Distance: 3,195.8 km
  • Duration: 11h 26m

What companies run services between Manzanillo, Mexico and Panama City, Panama?

You can take a bus from Parada en Av. Elias Zamora Verduzco to Terminal Tica Bus Panamá via Parada en Obras Maritimas 42, Manzanillo, Nueva Central Camionera de Guadalajara Mod 1 1/2, Guadalajara, Los Angeles, San Salvador, Terminal Tica Bus San Salvador, and Terminal Tica Bus San José in around 7d 11h. Alternatively, Aeroméxico and Copa Airlines fly from Playa De Oro International Airport (ZLO) to Tocumen International Airport (PTY) 4 times a day.

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