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How to get fromManzanillo to San Diegoby plane, bus, car, or train

Find Transport to San Diego

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There are 6 ways to get from Manzanillo to San Diego by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Playa De Oro International Airport (ZLO) to San Diego International Airport (SAN)plane plane ZLO - SAN
    6h 6m
    $209–846

  2. Bus

    cheapest
    1. Take the bus from Manzanillo to Tijuanabus bus
    2. Take the bus from Otay Mesa Transit Center to Broadway & 4th Avbus bus 225
    40h 25m
    $203–317

  3. Bus via Santa Ana

    1. Take the bus from Manzanillo to Santa Anabus bus
    2. Take the bus from Santa Ana to Mexicalibus bus
    3. Take the bus from Mexicali to Tijuanabus bus
    28h 46m
    $206–380

  4. Drive  1,525.7 mi

    1. Drive from Manzanillo to San Diegocar car 1,525.7 mi
    29h 30m
    $279–403

  5. Bus, drive, train

    1. Take the bus from Manzanillo to Santa Anabus bus
    2. Drive from Santa Ana to 219 N Arroyo Blvd - Nogalescar car
    3. Take the bus from 219 N Arroyo Blvd - Nogales to 4207 S 6th Ave - Tucsonbus bus
    4. Take the train from Tucson Amtrak Station to Los Angelestrain train
    5. Take the train from Los Angeles to San Diegotrain train
    35h 19m
    $542–843

  6. Bus #2

    1. Take the bus from Manzanillo to Nueva Central Camionera de Guadalajara Mod 1bus bus
    2. Take the bus from Nueva Central Camionera de Guadalajara Mod 6 to Tijuanabus bus
    46h 58m
    $209–455

Playa De Oro International Airport (ZLO) to San Diego International Airport (SAN) flights

Calendar12Weekly Planes
Duration7h 33mAverage Duration
Ticket$178Cheapest Price
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Comparing Your Travel Options

Map of how to get from Manzanillo to San Diego.ExpandLaunch map view
  • Distance: 1,240.6 mi
  • Duration: 6h 6m

What companies run services between Manzanillo, Mexico and San Diego, CA, USA?

American Airlines, United Airlines, and two other airlines fly from Playa De Oro International Airport (ZLO) to San Diego International Airport (SAN) twice daily. Alternatively, you can take a bus from Parada en Av. Elias Zamora Verduzco to Fifth Avenue Station via Parada en Obras Maritimas 42, Manzanillo, Santa Ana, Mexicali, Tijuana, and San Ysidro Station in around 28h 46m.

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