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How to get fromMassachusetts to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 10 ways to get from Massachusetts to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Boston Logan Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Des Moines (DSM)plane plane BOS - DSM
    4h 51m
    $189–823

  2. Fly from Bradley International Airport

    cheapest
    1. Fly from Bradley International Airport (BDL) to Des Moines (DSM)plane plane BDL - DSM
    6h 35m
    $183–784

  3. Bus

    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    29h 45m
    $224–395

  4. Train, bus

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    30h 1m
    $383–767

  5. Drive 1,295.8 mi

    1. Drive from Boston to Des Moinescar car 1,295.8 mi
    22h 2m
    $237–342

  6. Bus to Manchester Airport, fly

    1. Take the bus from Boston to Boston Manchester Airportbus bus
    2. Fly from Manchester Airport (MHT) to Des Moines (DSM)plane plane MHT - DSM
    7h 6m
    $215–936

  7. Train to Theodore Francis Green State Airport, fly

    1. Take the train from South Station to TF Green Airporttrain train
    2. Fly from Theodore Francis Green State Airport (PVD) to Des Moines (DSM)plane plane PVD - DSM
    7h 54m
    $187–787

  8. Fly from Worcester Regional Airport

    1. Fly from Worcester Regional Airport (ORH) to Des Moines (DSM)plane plane ORH - DSM
    6h 52m
    $199–823

  9. Train, train to Laguardia Airport, fly

    1. Take the train from Springfield to New Haventrain train
    2. Take the train from New Haven to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Des Moines (DSM)plane plane LGA - DSM
    8h 26m
    $258–1,048

  10. Train, bus via Galesburg

    1. Take the train from Boston to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    31h 53m
    $413–842

Massachusetts to Des Moines by bus

Calendar15Weekly Buses
Duration29h 45mAverage Duration
Ticket$224Cheapest Price
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Questions & Answers

Map of how to get from Massachusetts to Des Moines.ExpandLaunch map view
  • Distance: 1,170.6 mi
  • Duration: 4h 51m

What companies run services between Massachusetts, USA and Des Moines, IA, USA?

Allegiant Air, Delta, and three other airlines fly from Boston Logan Airport (BOS) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Boston to Des Moines via New York Midtown and Chicago Bus Station in around 29h 45m.

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