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How to get fromMassachusetts to Knoxvilleby plane, train, bus, car, bus (Flixbus), or bus (Greyhound)

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There are 9 ways to get from Massachusetts to Knoxville by plane, train, bus, car, bus (Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Mcghee Tyson Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS)plane plane BOS - TYS
    4h 16m
    $297–1,372

  2. Fly Boston Logan Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Boston Logan Airport (BOS) to Asheville Regional Airport (AVL)plane plane BOS - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 4m
    $112–502

  3. Train, bus via Farragut

    1. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the bus from New York to Knoxvillebus bus Nyc
    17h 35m
    $237–967

  4. Drive  909.8 mi

    1. Drive from Boston to Knoxvillecar car 909.8 mi
    15h 57m
    $156–225

  5. Train to Bradley International Airport, fly to Mcghee Tyson Airport

    1. Take the train from Springfield to Hartford Amtrak Stationtrain train
    2. Fly from Bradley International Airport (BDL) to Mcghee Tyson Airport (TYS)plane plane BDL - TYS
    6h 59m
    $291–1,294

  6. Train to Theodore Francis Green State Airport, fly to Mcghee Tyson Airport

    1. Take the train from South Station to TF Green Airporttrain train
    2. Fly from Theodore Francis Green State Airport (PVD) to Mcghee Tyson Airport (TYS)plane plane PVD - TYS
    7h 9m
    $285–1,286

  7. Train, bus

    1. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train Northeast Regional
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    17h 39m
    $192–877

  8. Bus

    1. Take the bus from Boston to NYC Downtownbus bus FlixBus 2611
    2. Take the bus from New York to Knoxvillebus bus Nyc
    18h 6m
    $214–300

  9. Bus via New York

    1. Take the bus from Boston to Port Authority Bus Terminalbus bus Greyhound US0230 / ...
    2. Take the bus from New York to Knoxvillebus bus Nyc
    18h 27m
    $223–312

Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS) flights

Calendar68Weekly Planes
Duration4h 40mAverage Duration
Ticket$242Cheapest Price
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Comparing Your Travel Options

Map of how to get from Massachusetts to Knoxville.ExpandLaunch map view
  • Distance: 844.9 mi
  • Duration: 4h 16m

What companies run services between Massachusetts, USA and Knoxville, TN, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Boston Logan Airport (BOS) to Mcghee Tyson Airport (TYS) every 3 hours. Alternatively, you can take a bus from Boston to Knoxville via NYC Downtown, New York, and Knoxville in around 18h 6m.

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