There are 8 ways to get from Massachusetts to Louisville by plane, train, bus, bus (Greyhound, Flixbus, Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Boston Logan Airport to Louisville International Airport
best- Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane BOS - SDF
5h 22m$153–805Fly Bradley International Airport to Louisville International Airport
cheapest- Fly from Bradley International Airport (BDL) to Louisville International Airport (SDF)plane BDL - SDF
7h 5m$150–818Train, bus via Toledo
- Take the train from Boston to Toledotrain
- Take the bus from Toledo to Indianapolisbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
25h 23m$476–774Bus
- Take the bus from Boston to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Louisville, KYbus
25h 40m$181–301Drive 937 mi
- Drive from Boston to Louisvillecar 937 mi
16h 51m$171–247Train, train to Laguardia Airport, fly to Louisville International Airport
- Take the train from Springfield to New Haventrain
- Take the train from New Haven to 125th Street - Harlemtrain
- Fly from Laguardia Airport (LGA) to Louisville International Airport (SDF)plane LGA - SDF
8h 48m$216–992Train, train to Laguardia Airport, fly to Blue Grass Airport, drive
- Take the train from Springfield to New Haventrain
- Take the train from New Haven to 125th Street - Harlemtrain
- Fly from Laguardia Airport (LGA) to Blue Grass Airport (LEX)plane LGA - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
8h 37m$153–608Train, bus (Amtrak)
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
31h 12m$576–1,559
Massachusetts to Louisville by train and bus
Comparing Your Travel Options
The cheapest way to get from Massachusetts to Louisville is to drive which costs $170 - $250 and takes 16h 51m.
The fastest way to get from Massachusetts to Louisville is to fly which takes 5h 22m and costs $150 - $850.
No, there is no direct bus from Massachusetts to Louisville. However, there are services departing from Boston and arriving at Louisville, KY via Newark Penn Station and Indianapolis Union Station. The journey, including transfers, takes approximately 25h 40m.
The distance between Massachusetts and Louisville is 841 miles. The road distance is 942.5 miles.
The best way to get from Massachusetts to Louisville without a car is to train and bus via Toledo which takes 25h 23m and costs $470 - $800.
It takes approximately 5h 22m to get from Massachusetts to Louisville, including transfers.
Massachusetts to Louisville bus services, operated by Greyhound USA, depart from Boston station.
The best way to get from Massachusetts to Louisville is to fly which takes 5h 22m and costs $150 - $850. Alternatively, you can bus, which costs $180 - $310 and takes 25h 40m.
Massachusetts to Louisville bus services, operated by Greyhound USA, arrive at Newark Penn Station.
Yes, the driving distance between Massachusetts to Louisville is 942 miles. It takes approximately 16h 51m to drive from Massachusetts to Louisville.
What companies run services between Massachusetts, USA and Louisville, KY, USA?
American Airlines, Delta, and two other airlines fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF) every 4 hours. Alternatively, you can take a bus from Boston to Louisville, KY via Newark Penn Station and Indianapolis Union Station in around 25h 40m.
- Website
- delta.com
Flights from Boston Logan Airport to Louisville International Airport
- Ave. Duration
- 2h 42m
- When
- Every day
- Estimated price
- $150–800
Flights from Boston Logan Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Bradley International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $150–850
Flights from Laguardia Airport to Louisville International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $160–900
Flights from Laguardia Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 28m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–950
Flights from Laguardia Airport to Blue Grass Airport
- Ave. Duration
- 2h 9m
- When
- Every day
- Estimated price
- $85–500
Flights from Laguardia Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $100–550
Flights from Laguardia Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $120–650
- Website
- aa.com
Flights from Boston Logan Airport to Louisville International Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $150–800
Flights from Boston Logan Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 4h 59m
- When
- Monday to Saturday
- Estimated price
- $150–800
Flights from Bradley International Airport to Louisville International Airport via Philadelphia
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $140–800
Flights from Bradley International Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 5h 50m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $150–800
Flights from Laguardia Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 4h 39m
- When
- Sunday
- Estimated price
- $160–900
Flights from Laguardia Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Laguardia Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $100–600
- Website
- southwest.com
Flights from Boston Logan Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $150–800
Flights from Boston Logan Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 50m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–900
Flights from Bradley International Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $150–800
Flights from Bradley International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 7h 5m
- When
- Sunday and Saturday
- Estimated price
- $170–900
Flights from Laguardia Airport to Louisville International Airport via Nashville
- Ave. Duration
- 5h
- When
- Tuesday and Wednesday
- Estimated price
- $190–1,000
- Website
- united.com
Flights from Boston Logan Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $150–800
Flights from Bradley International Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $140–800
Flights from Laguardia Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $160–900
Flights from Laguardia Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Toledo
- Ave. Duration
- 17h 23m
- Frequency
- Once daily
- Estimated price
- $430–700
- Website
- Amtrak
Train from Springfield to New Haven
- Ave. Duration
- 1h 22m
- Frequency
- Every 3 hours
- Estimated price
- $30–55
- Website
- Amtrak
Train from Springfield to New Haven
- Ave. Duration
- 1h 22m
- Frequency
- Every 3 hours
- Estimated price
- $30–55
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 4h 2m
- Frequency
- Every 3 hours
- Estimated price
- $120–200
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Indianapolis
- Ave. Duration
- 23h 15m
- Frequency
- 3 times a week
- Estimated price
- $500–800
- Website
- Amtrak
- Phone
- +1 877.690.5114
- Website
- Metro North Railroad
Train from New Haven to 125th Street - Harlem
- Ave. Duration
- 1h 55m
- Frequency
- Every 30 minutes
- Estimated price
- $18–28
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $18–21
- Peak
- $25–28
Train from New Haven to 125th Street - Harlem
- Ave. Duration
- 1h 55m
- Frequency
- Every 30 minutes
- Estimated price
- $18–28
- Website
- Metro North Railroad
- Schedules at
- Metro North Railroad Schedules
- Off-Peak
- $18–21
- Peak
- $25–28
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 49m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $50–490
- First Class
- $200–750
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Toledo to Indianapolis
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Newark Penn Station
- Ave. Duration
- 5h 20m
- Frequency
- 4 times a day
- Estimated price
- $40–70
- Website
- Greyhound
Bus from Newark Penn Station to Indianapolis Union Station
- Ave. Duration
- 16h 25m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
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Booking & Getting There
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