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How to get fromMassachusetts to Missouriby plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

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There are 8 ways to get from Massachusetts to Missouri by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Boston Logan Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    5h 7m
    $365–855

  2. Fly Worcester Regional Airport to Lambert–St. Louis International Airport

    cheapest
    1. Fly from Worcester Regional Airport (ORH) to Lambert–St. Louis International Airport (STL)plane plane ORH - STL
    7h 14m
    $125–655

  3. Train (Amtrak)

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    30h 57m
    $388–1,014

  4. Bus

    1. Take the bus from Boston to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    33h 50m
    $239–380

  5. Drive  1,390.5 mi

    1. Drive from Boston to Kansas Citycar car 1,390.5 mi
    24h 26m
    $254–367

  6. Fly Boston Logan Airport to Kansas City

    1. Fly from Boston Logan Airport (BOS) to Kansas City (MCI)plane plane BOS - MCI
    6h 37m
    $302–1,002

  7. Train, train to Laguardia Airport, fly to Lambert–St. Louis International Airport

    1. Take the train from Springfield to New Haventrain train
    2. Take the train from New Haven to 125th Street - Harlemtrain train
    3. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    8h 32m
    $181–522

  8. Bus, train

    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    34h 29m
    $292–588

Massachusetts to Missouri by train and tram (Amtrak)

Calendar7Weekly Services
Duration30h 57mAverage Duration
Ticket$388Cheapest Price
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Comparing Your Travel Options

Map of how to get from Massachusetts to Missouri.ExpandLaunch map view
  • Distance: 1,060.7 mi
  • Duration: 5h 7m

What companies run services between Massachusetts, USA and Missouri, USA?

American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a train from Boston to Metro Center via Chicago Union Station, Kansas City, and Union Station in around 30h 57m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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