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How to get fromMastic to Syracuseby train, bus (Greyhound), car, plane, or bus

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There are 9 ways to get from Mastic to Syracuse by train, bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Mastic-Shirley to Jamaicatrain train Montauk Branch
    2. Take the train from New York Penn Station to Syracusetrain train VIA Rail
    8h 21m
    $116–311

  2. Drive 292.8 mi

    cheapest
    1. Drive from Mastic to Syracusecar car 292.8 mi
    6h 30m
    $54–78

  3. Bus

    1. Take the bus from Riverhead to 3 Av & E 42 Stbus bus North Fork
    2. Take the bus from Port Authority Bus Terminal to Syracuse Bus Stationbus bus Greyhound US0205 / ...
    9h 58m
    $74–245

  4. Train to John F. Kennedy International Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Patchogue to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Syracuse Hancock International Airport (SYR)plane plane JFK - SYR
    7h 17m
    $99–596

  5. Bus, train

    1. Take the bus from Patchogue LIRR to Amityville LIRRbus bus 2
    2. Take the train from Amityville to New York Penn Stationtrain train
    3. Take the bus from New York Midtown to Syracuse Bus Stationbus bus
    10h 6m
    $60–101

  6. Line 66 bus, train, bus to Laguardia Airport, fly to Syracuse Hancock International Airport

    1. Take the bus from Mastic Rd/Patchogue Ave to Patchogue LIRRbus bus
    2. Take the train from Patchogue to Jamaicatrain train
    3. Take the bus from Junction Blvd/Queens Blvd to Laguardia Rd/94 Stbus bus
    4. Fly from Laguardia Airport (LGA) to Syracuse Hancock International Airport (SYR)plane plane LGA - SYR
    8h 25m
    $116–698

  7. Train to John F. Kennedy International Airport, fly to Rochester, train

    1. Take the train from Patchogue to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Rochester (ROC)plane plane JFK - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 55m
    $132–700

  8. Train to John F. Kennedy International Airport, fly to Ithaca Tompkins Regional Airport, bus

    1. Take the train from Patchogue to Jamaicatrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Ithaca Tompkins Regional Airport (ITH)plane plane JFK - ITH
    3. Take the bus from Ithaca to Syracuse Bus Stationbus bus
    9h 8m
    $67–335

  9. Train to Laguardia Airport, fly to Rochester, train

    1. Take the train from Patchogue to Jamaicatrain train
    2. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    9h 16m
    $154–872

Mastic to Syracuse by bus and train

Calendar47Weekly Services
Duration10h 6mAverage Duration
Ticket$60Cheapest Price
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Questions & Answers

Map of how to get from Mastic to Syracuse.ExpandLaunch map view
  • Distance: 355.2 mi
  • Duration: 8h 21m

What companies run services between Mastic, NY, USA and Syracuse, NY, USA?

You can take a vehicle from Mastic to Syracuse via Mastic-Shirley, Jamaica, and New York Penn Station in around 8h 21m. Alternatively, you can take a bus from Mastic Rd/Patchogue Ave to Syracuse Bus Station via Riverhead, 3 Av & E 42 St, E 42 St/3 Av, West 42nd Street & 8th Avenue, and Port Authority Bus Terminal in around 9h 58m.

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