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How to get fromMatamoros to Panama Cityby plane, bus, or car

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There are 6 ways to get from Matamoros to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Servando Canales International Airport

    best
    1. Fly from General Servando Canales International Airport (MAM) to Tocumen International Airport (PTY)plane plane MAM - PTY
    12h 55m
    $262–942

  2. Fly from Brownsville-South Padre Island International Airport

    cheapest
    1. Fly from Brownsville-South Padre Island International Airport (BRO) to Tocumen International Airport (PTY)plane plane BRO - PTY
    10h 12m
    $190–640

  3. Bus via Mexico City

    1. Take the bus from Matamoros to Terminal Central de Autobuses del Nortebus bus
    2. Take the bus from Politécnico to Tapachulabus bus
    3. Take the bus from Tapachula to San Salvadorbus bus
    4. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    3d 4h
    $275–505

  4. Drive 3,754.2 km

    1. Drive from Matamoros to Panama Citycar car 3,754.2 km
    2d 5h
    $514–742

  5. Bus to Mcallen Miller International Airport, fly

    1. Take the bus from Brownsville to McAllen Central Stationbus bus
    2. Fly from Mcallen Miller International Airport (MFE) to Tocumen International Airport (PTY)plane plane MFE - PTY
    10h 23m
    $235–899

  6. Bus

    1. Take the bus from Matamoros to Veracruzbus bus
    2. Take the bus from Veracruz to Tapachulabus bus
    3. Take the bus from Tapachula to San Salvadorbus bus
    4. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus Sac
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    3d 8h
    $354–530

General Servando Canales International Airport (MAM) to Tocumen International Airport (PTY) flights

Calendar18Weekly Planes
Duration17h 1mAverage Duration
Ticket$224Cheapest Price
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Questions & Answers

Map of how to get from Matamoros to Panama City.ExpandLaunch map view
  • Distance: 2,705.9 km
  • Duration: 12h 55m

What companies run services between Matamoros, Tamaulipas, Mexico and Panama City, Panama?

Aeroméxico, Copa Airlines, and two other airlines fly from General Servando Canales International Airport (MAM) to Tocumen International Airport (PTY) 3 times a day. Alternatively, you can take a bus from Matamoros to Terminal Tica Bus Panamá via México D.F., Central De Autobuses Del Norte, Autobuses del Norte, Politécnico, Politécnico, Tapachula, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, and Terminal Tica Bus San José in around 3d 4h.

Airlines
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