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How to get fromMatamoros to San Antonioby bus (Flixbus, Greyhound), car, plane, or bus

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There are 5 ways to get from Matamoros to San Antonio by bus (Flixbus, Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from La Plaza at Brownsville to San Antonio Bus Stationbus bus FlixBus US1120 / ...
    6h 10m
    $45–80

  2. Drive  279 mi

    1. Drive from Matamoros to San Antoniocar car 279 mi
    4h 47m
    $61–89

  3. Fly Brownsville-South Padre Island International Airport to San Antonio International Airport

    1. Fly from Brownsville-South Padre Island International Airport (BRO) to San Antonio International Airport (SAT)plane plane BRO - SAT
    5h 49m
    $79–464

  4. Bus to Rio Grande Valley International Airport, fly to San Antonio International Airport

    1. Take the bus from Brownsville to Harlingen Bus Stationbus bus
    2. Fly from Rio Grande Valley International Airport (HRL) to San Antonio International Airport (SAT)plane plane HRL - SAT
    6h 36m
    $118–503

  5. Bus to Mcallen Miller International Airport, fly to Austin-Bergstrom International Airport, bus

    1. Take the bus from Brownsville to McAllen Central Stationbus bus
    2. Fly from Mcallen Miller International Airport (MFE) to Austin-Bergstrom International Airport (AUS)plane plane MFE - AUS
    3. Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus bus
    6h 59m
    $87–481

Matamoros to San Antonio by bus

Calendar27Weekly Buses
Duration6h 10mAverage Duration
Ticket$45Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Matamoros to San Antonio.ExpandLaunch map view
  • Distance: 298.1 mi
  • Duration: 6h 10m

What companies run services between Matamoros, Tamaulipas, Mexico and San Antonio, TX, USA?

Flixbus USA operates a bus from La Plaza at Brownsville to San Antonio Bus Station 3 times a day. Tickets cost $45–70 and the journey takes 6h 10m. Two other operators also service this route. Alternatively, United Airlines and American Airlines fly from Brownsville-South Padre Island International Airport (BRO) to San Antonio International Airport (SAT) every 4 hours.

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Want to know more about travelling around United States

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Need to know: Greyhound

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