There are 5 ways to get from Matanzas to Santiago de Cuba by bus, plane, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to José Martí International Airport, fly
best- Take the bus from Matanzas to Havana Airportbus
- Fly from José Martí International Airport (HAV) to Antonio Maceo International Airport (SCU)plane HAV - SCU
5h 12m$445–1,220Bus
cheapest- Take the bus from Matanzas to Santiago de Cubabus Matanzas
10h$5–11Train
- Take the train from Matanzas to Santiago de Cubatrain 11
15h 15m$5–14Drive 806.3 km
- Drive from Matanzas to Santiago de Cubacar 806.3 km
11h 22m$92–133Bus to Abel Santamaría Airport, fly
- Take the bus from Matanzas to Santa Clarabus
- Fly from Abel Santamaría Airport (SNU) to Antonio Maceo International Airport (SCU)plane SNU - SCU
23h 58m$106–480
José Martí International Airport (HAV) to Antonio Maceo International Airport (SCU) flights
Questions & Answers
The cheapest way to get from Matanzas to Santiago de Cuba is to train which costs $4 - $14 and takes 15h 15m.
The fastest way to get from Matanzas to Santiago de Cuba is to bus and fly which takes 5h 12m and costs $440 - $1,300.
Yes, there is a direct bus departing from Matanzas and arriving at Santiago de Cuba. Services depart once daily, and operate every day. The journey takes approximately 10h.
Yes, there is a direct train departing from Matanzas and arriving at Santiago de Cuba. Services depart once a week. The journey takes approximately 15h 15m.
The distance between Matanzas and Santiago de Cuba is 884 km. The road distance is 806.3 km.
The best way to get from Matanzas to Santiago de Cuba without a car is to bus which takes 10h and costs $5 - $11.
It takes approximately 5h 12m to get from Matanzas to Santiago de Cuba, including transfers.
Matanzas to Santiago de Cuba bus services, operated by Ómnibus Nacionales, depart from Matanzas station.
Matanzas to Santiago de Cuba train services, operated by Ferrocarriles de Cuba, depart from Matanzas station.
The best way to get from Matanzas to Santiago de Cuba is to bus which takes 10h and costs $5 - $11. Alternatively, you can train, which costs $4 - $14 and takes 15h 15m.
What companies run services between Matanzas, Cuba and Santiago de Cuba?
Ómnibus Nacionales operates a bus from Matanzas to Santiago de Cuba once daily. Tickets cost $5–11 and the journey takes 10h. Alternatively, Ferrocarriles de Cuba operates a train from Matanzas to Santiago de Cuba once a week. Tickets cost $5–14 and the journey takes 15h 15m.
Flights from José Martí International Airport to Antonio Maceo International Airport
- Ave. Duration
- 1h 26m
- When
- Wednesday and Tuesday
- Estimated price
- $180–650
- Website
- aa.com
Flights from Abel Santamaría Airport to Antonio Maceo International Airport via Miami
- Ave. Duration
- 19h 30m
- When
- Wednesday to Sunday
- Estimated price
- $90–460
- Phone
- +53 7 855 5025 / 7 855 5026 / 5 2161205
- [email protected]
- Website
- facebook.com
Train from Matanzas to Santiago de Cuba
- Ave. Duration
- 15h 15m
- Frequency
- Once a week
- Estimated price
- $5–14
- Schedules at
- https://thebusschedule.com/EN/cu/index.php
- Normal
- $5
- Climatizado
- $7
- Phone
- +53 59 89 0616
- [email protected]
- Website
- viazul.wetransp.com
Bus from Matanzas to Havana Airport
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $12–18
- Website
- https://www.viazul.wetransp.com/
- Phone
- +53 7873 7373
- [email protected]
- Website
- eon.wetransp.com
Bus from Matanzas to Santiago de Cuba
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $5–11
- Schedules at
- eon.wetransp.com
Bus from Matanzas to Santa Clara
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $1–3
- Schedules at
- eon.wetransp.com
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More Questions & Answers
Matanzas to Santiago de Cuba bus services, operated by Ómnibus Nacionales, arrive at Santiago de Cuba station.
Matanzas to Santiago de Cuba train services, operated by Ferrocarriles de Cuba, arrive at Santiago de Cuba station.
Yes, the driving distance between Matanzas to Santiago de Cuba is 806 km. It takes approximately 11h 22m to drive from Matanzas to Santiago de Cuba.










