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How to get fromMattoon to Great Smoky Mountainsby train, plane, car, or bus

Find Transport to Great Smoky Mountains

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There are 10 ways to get from Mattoon to Great Smoky Mountains by train, plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to University Of Illinois Willard Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS)plane plane CMI - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    8h 18m
    $162–717

  2. Drive 491.4 mi

    cheapest
    1. Drive from Mattoon to Great Smoky Mountainscar car 491.4 mi
    10h 42m
    $90–130

  3. Train, bus, drive via Columbus

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Columbusbus bus
    4. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    25h 29m
    $154–314

  4. Train, bus, drive

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the train from Indianapolis to Charlottesvilletrain train
    4. Take the train from Charlottesville to Greensborotrain train
    5. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    6. Drive from Asheville, NC to Great Smoky Mountainscar car
    31h 7m
    $316–654

  5. Train to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    9h 8m
    $168–735

  6. Train, bus to Decatur Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus bus
    3. Fly from Decatur Airport (DEC) to Mcghee Tyson Airport (TYS)plane plane DEC - TYS
    4. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    12h 32m
    $165–775

  7. Train, bus to Central Illinois Regional Airport At Bloomington-Normal, fly to Mcghee Tyson Airport, drive

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Bloomington-Normalbus bus
    3. Fly from Central Illinois Regional Airport At Bloomington-Normal (BMI) to Mcghee Tyson Airport (TYS)plane plane BMI - TYS
    4. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    10h 44m
    $152–711

  8. Train, bus to Decatur Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus bus
    3. Fly from Decatur Airport (DEC) to Asheville Regional Airport (AVL)plane plane DEC - AVL
    4. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    12h 46m
    $124–471

  9. Train, bus, drive via Ironville

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    4. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    5. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    6. Drive from New Leicester Hwy at Walgreens to Great Smoky Mountainscar car
    26h 23m
    $198–399

  10. Train, bus, drive #2

    1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Greensborotrain train
    4. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    5. Drive from Asheville, NC to Great Smoky Mountainscar car
    37h 32m
    $468–984

University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS) flights

Calendar36Weekly Planes
Duration5h 55mAverage Duration
Ticket$122Cheapest Price
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Questions & Answers

Map of how to get from Mattoon to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 483.4 mi
  • Duration: 8h 18m

What companies run services between Mattoon, IL, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Mattoon to Great Smoky Mountains. However, you can take the train to Champaign-Urbana, take the taxi to University Of Illinois Willard Airport (CMI) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a train from Mattoon Amtrak Station to Great Smoky Mountains via Champaign-Urbana, Champaign Intermodal Trans Ctr, Indianapolis Union Station, Columbus, Winston Salem(Trans Center), and Asheville, NC in around 25h 29m.

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