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How to get fromMattoon to Iowaby train, bus, car, or plane

Find Transport to Iowa

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There are 5 ways to get from Mattoon to Iowa by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train Saluki / ...
    2. Take the bus from Champaign Intermodal Trans Ctr to Des Moinesbus bus Greyhound US0157S
    9h 36m
    $93–138

  2. Drive  381.7 mi

    cheapest
    1. Drive from Mattoon to Des Moinescar car 381.7 mi
    7h 4m
    $70–101

  3. Train to University Of Illinois Willard Airport, fly

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Quad City International Airport (MLI)plane plane CMI - MLI
    7h 23m
    $90–382

  4. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Mattoon Amtrak Station to Homewoodtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    8h 29m
    $120–379

  5. Train, bus to Decatur Airport, fly

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Decatur Downtown Transportation Centerbus bus
    3. Fly from Decatur Airport (DEC) to Quad City International Airport (MLI)plane plane DEC - MLI
    9h 27m
    $93–389

University Of Illinois Willard Airport (CMI) to Quad City International Airport (MLI) flights

Calendar23Weekly Planes
Duration5h 34mAverage Duration
Ticket$47Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Mattoon to Iowa.ExpandLaunch map view
  • Distance: 389.1 mi
  • Duration: 9h 36m

What companies run services between Mattoon, IL, USA and Iowa, USA?

There is no direct connection from Mattoon to Iowa. However, you can take the train to Champaign-Urbana, walk to Champaign Intermodal Trans Ctr, take the bus to Des Moines, then take the taxi to Des Moines. Alternatively, you can drive from Mattoon to Des Moines in around 7h 4m.

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