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How to get fromMattoon to Knoxvilleby taxi, plane, train, bus, or car

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There are 8 ways to get from Mattoon to Knoxville by taxi, plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Decatur Airport, fly

    best
    1. Take the taxi from Mattoon to Decatur Airport (DEC)taxi taxi
    2. Fly from Decatur Airport (DEC) to Mcghee Tyson Airport (TYS)plane plane DEC - TYS
    8h 2m
    $290–895

  2. Drive 435 mi

    cheapest
    1. Drive from Mattoon to Knoxvillecar car 435 mi
    8h 53m
    $80–115

  3. Train, bus via Chicago

    1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    38h 12m
    $550–1,017

  4. Train, bus

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    4. Take the bus from New York to Knoxvillebus bus Nyc
    38h 23m
    $337–562

  5. Train to University Of Illinois Willard Airport, fly

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS)plane plane CMI - TYS
    6h 43m
    $208–821

  6. Train to Chicago O'Hare International Airport, fly

    1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    7h 33m
    $214–789

  7. Train, bus via Ossining

    1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    38h 49m
    $505–944

  8. Train, bus via Champaign

    1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain train
    2. Take the bus from Champaign Intermodal Trans Ctr to Chicagobus bus
    3. Take the bus from Chicago to New York City Chinatownbus bus
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    42h 23m
    $283–439

Decatur Airport (DEC) to Mcghee Tyson Airport (TYS) flights

Calendar17Weekly Planes
Duration10h 21mAverage Duration
Ticket$129Cheapest Price
See schedules

Questions & Answers

Map of how to get from Mattoon to Knoxville.ExpandLaunch map view
  • Distance: 439.2 mi
  • Duration: 8h 2m

What companies run services between Mattoon, IL, USA and Knoxville, TN, USA?

There is no direct connection from Mattoon to Knoxville. However, you can take the taxi to Decatur Airport (DEC) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from Mattoon Amtrak Station to Knoxville via Chicago Union Station, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 38h 12m.

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