What is the cheapest way to get from Mattoon to Mayo Clinic?

The cheapest way to get from Mattoon to Mayo Clinic is to drive which costs $80 - $120 and takes 9h 6m.

What is the fastest way to get from Mattoon to Mayo Clinic?

The fastest way to get from Mattoon to Mayo Clinic is to train and fly which takes 7h 1m and costs $85 - $420.

Is there a direct bus between Mattoon and Mayo Clinic?

No, there is no direct bus from Mattoon station to Mayo Clinic. However, there are services departing from Phillips Gas Station - Arcola and arriving at Rochester via Milwaukee. The journey, including transfers, takes approximately 12h 7m.

How far is it from Mattoon to Mayo Clinic?

The distance between Mattoon and Mayo Clinic is 407 miles. The road distance is 453.7 miles.

How do I travel from Mattoon to Mayo Clinic without a car?

The best way to get from Mattoon to Mayo Clinic without a car is to bus which takes 12h 7m and costs $170 - $320.

How long does it take to get from Mattoon to Mayo Clinic?

It takes approximately 7h 1m to get from Mattoon to Mayo Clinic, including transfers.

Where do I catch the Mattoon to Mayo Clinic bus from?

Mattoon to Mayo Clinic bus services, operated by Tornado Bus Company, depart from Phillips Gas Station - Arcola.

Where does the Mattoon to Mayo Clinic bus arrive?

Mattoon to Mayo Clinic bus services, operated by Tornado Bus Company, arrive at Water & Chicago - Circle K station.

Can I drive from Mattoon to Mayo Clinic?

Yes, the driving distance between Mattoon to Mayo Clinic is 454 miles. It takes approximately 9h 6m to drive from Mattoon to Mayo Clinic.

Where can I stay near Mayo Clinic?

There are 73+ hotels available in Mayo Clinic.

Mattoon to Mayo Clinic - 8 ways to travel via train, plane, bus, and car

How to get fromMattoon to Mayo Clinic

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There are 8 ways to get from Mattoon to Mayo Clinic by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Train to University Of Illinois Willard Airport, fly
best
1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain
2. Fly from University Of Illinois Willard Airport (CMI) to Rochester (RST)plane CMI - RST
7h 1m
$89–411
Train, bus to Central Illinois Regional Airport At Bloomington-Normal, fly
cheapest
1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain
2. Take the bus from Champaign Intermodal Trans Ctr to Bloomington-Normalbus
3. Fly from Central Illinois Regional Airport At Bloomington-Normal (BMI) to Rochester (RST)plane BMI - RST
11h 12m
$75–406
Bus
1. Take the bus from Phillips Gas Station - Arcola to Water & Chicago - Circle Kbus Milwaukee
2. Take the bus from Milwaukee to Rochesterbus Jefferson 966 / ...
12h 7m
$171–318
Train, bus
1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain
2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain
3. Take the bus from St. Paul to Rochester, MNbus
14h 36m
$214–423
Drive 451 mi
1. Drive from Mattoon to Mayo Cliniccar 451 mi
9h 6m
$83–119
Train to Chicago O'Hare International Airport, fly
1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain
2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane ORD - RST
8h 10m
$104–448
Train, bus via Madison
1. Take the train from Mattoon Amtrak Station to Chicago Union Stationtrain
2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
3. Take the bus from Madison to Rochesterbus
13h 33m
$131–243
Train, bus via Lake Delton
1. Take the train from Mattoon Amtrak Station to Champaign-Urbanatrain
2. Take the bus from Champaign Intermodal Trans Ctr to Chicago Bus Stationbus
3. Take the bus from Chicago Bus Station to Wisconsin Dellsbus
4. Take the bus from Wisconsin Dells to Rochester, MNbus
14h 4m
$135–219

Mattoon to Mayo Clinic by train, bus, and foot

14Weekly Services

14h 36mAverage Duration

$214Cheapest Price

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Questions & Answers

Map of how to get from Mattoon to Mayo Clinic.

Launch map view

Distance: 404.4 mi
Duration: 7h 1m

What companies run services between Mattoon, IL, USA and Mayo Clinic, MN, USA?

You can take a vehicle from Mattoon to Mayo Clinic via Phillips Gas Station - Arcola, Water & Chicago - Circle K, Milwaukee, and Rochester in around 12h 7m.

Airlines

Train operators

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