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How to get fromMayfield Heights to Chicagoby bus, plane, train (Amtrak), car, or bus (Greyhound)

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There are 6 ways to get from Mayfield Heights to Chicago by bus, plane, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 9 bus, fly to Chicago Midway International Airport

    best
    1. Take the bus from Mayfield Rd & Commonwealth Av to Prospect Av & W 3Rd Stbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    4h 31m
    $68–380

  2. Bus

    cheapest
    1. Take the bus from Cleveland to Chicagobus bus Cleveland
    9h 47m
    $40–90

  3. Train (Amtrak)

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    9h 9m
    $112–232

  4. Drive 357.5 mi

    1. Drive from Mayfield Heights to Chicagocar car 357.5 mi
    5h 58m
    $66–95

  5. Line 9 bus, fly to Chicago O'Hare International Airport

    1. Take the bus from Mayfield Rd & Commonwealth Av to Prospect Av & W 3Rd Stbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane plane CLE - ORD
    4h 56m
    $378–810

  6. Bus via Brook Park (Greyhound)

    1. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    10h 8m
    $60–116

Mayfield Heights to Chicago by bus

Calendar7Weekly Buses
Duration9h 47mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

Map of how to get from Mayfield Heights to Chicago.ExpandLaunch map view
  • Distance: 344.5 mi
  • Duration: 4h 31m

What companies run services between Mayfield Heights, OH, USA and Chicago, IL, USA?

Amtrak operates a train from Cleveland Amtrak to Chicago Union Station 3 times a day. Tickets cost $110–230 and the journey takes 6h 46m. Alternatively, Barons Bus operates a bus from Cleveland to Chicago once daily. Tickets cost $35–85 and the journey takes 7h 35m.

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