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How to get fromMayo Clinic Arizona to Grand Canyonby bus, car, plane, shuttle, train, or bus (Flixbus)

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There are 6 ways to get from Mayo Clinic Arizona to Grand Canyon by bus, car, plane, shuttle, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Phoenix Denny's Deer Valley to Flagstaff Amtrak Stationbus bus Phx
    2. Take the bus from Flagstaff Amtrak Station to Grand Canyon Maswik Lodgebus bus Flagstaff
    5h 53m
    $135–215

  2. Drive 215.2 mi

    cheapest
    1. Drive from Mayo Clinic Arizona to Grand Canyoncar car 215.2 mi
    3h 50m
    $40–57

  3. Line 72 bus, fly, bus

    1. Take the bus from Scottsdale Rd & Mayo Bl to Rural Rd & Tyler Stbus bus
    2. Fly from Phoenix (PHX) to Flagstaff (FLG)plane plane PHX - FLG
    3. Take the bus from Flagstaff Pulliam Airport to Grand Canyon Maswik Lodgebus bus
    6h 52m
    $84–329

  4. Shuttle

    1. Take a shuttle bus from Sky Harbor International Airport to Grand Canyon Villageshuttle bus Phoenix
    6h 57m
    $282

  5. Bus, train

    1. Take the bus from Phoenix Denny's Deer Valley to Flagstaff University Northbus bus Phx
    2. Take the bus from Flagstaff Amtrak Station to Williams Grand Canyon Railway Resortbus bus
    3. Take the train from Williams, AR to Grand Canyontrain train
    7h 58m
    $179–435

  6. Bus via Rural Rd & Tyler St

    1. Take the bus from Tempe to Flagstaff Train Stationbus bus FlixBus 2047
    2. Take the bus from Flagstaff Amtrak Station to Grand Canyon Maswik Lodgebus bus Flagstaff
    8h 28m
    $76–122

Mayo Clinic Arizona to Grand Canyon by foot and bus

Calendar20Weekly Services
Duration8h 28mAverage Duration
Ticket$76Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic Arizona to Grand Canyon.ExpandLaunch map view
  • Distance: 240 mi
  • Duration: 5h 53m

What companies run services between Mayo Clinic Arizona, AZ, USA and Grand Canyon, AZ, USA?

You can take a vehicle from Mayo Clinic Arizona to Grand Canyon Maswik Lodge via Phoenix Denny's Deer Valley and Flagstaff Amtrak Station in around 5h 53m.

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Train operators
Bus operators

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