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How to get fromMayo Clinic to Ann Arborby plane, bus, bus (Flixbus), train, car, or bus (Amtrak)

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There are 8 ways to get from Mayo Clinic to Ann Arbor by plane, bus, bus (Flixbus), train, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Rochester to Detroit, bus

    best
    1. Fly from Rochester (RST) to Detroit (DTW)plane plane RST - DTW
    2. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    7h 37m
    $90–507

  2. Bus

    1. Take the bus from Rochester, MN to Milwaukee, WI - Amtrakbus bus Minneapolis / ...
    2. Take the bus from Milwaukee Intermodal Station to Ann Arborbus bus FlixBus 2550
    14h 8m
    $124–191

  3. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Ann Arbor Amtrak Stationtrain train
    15h 9m
    $234–469

  4. Drive 586.7 mi

    1. Drive from Mayo Clinic to Ann Arborcar car 586.7 mi
    9h 42m
    $108–155

  5. Bus to Minneapolis–Saint Paul International Airport, fly to Detroit, bus

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Detroit (DTW)plane plane MSP - DTW
    3. Take the bus from Detroit Metro Airport to Ann Arbor- Blake Transit Ctr., MIbus bus
    6h 7m
    $529–1,270

  6. Fly Rochester to Capital Region International Airport, bus

    1. Fly from Rochester (RST) to Capital Region International Airport (LAN)plane plane RST - LAN
    2. Take the bus from East Lansing, MI to Ann Arbor- Blake Transit Ctr., MIbus bus
    8h 57m
    $113–665

  7. Bus, train via Madison

    1. Take the bus from Rochester, MN to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Ann Arbor Amtrak Stationtrain train
    14h 55m
    $159–299

  8. Bus via Chicago

    1. Take the bus from Rochester, MN to UW-Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the bus from Chicago Union Station to Ann Arbor Amtrak Stationbus bus
    14h 55m
    $164–259

Mayo Clinic to Ann Arbor by foot and bus

Calendar4Weekly Services
Duration14h 8mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Ann Arbor.ExpandLaunch map view
  • Distance: 518.8 mi
  • Duration: 7h 37m

What companies run services between Mayo Clinic, MN, USA and Ann Arbor, MI, USA?

You can take a vehicle from Mayo Clinic to Ann Arbor via Rochester, MN and Milwaukee Intermodal Station in around 14h 8m.

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