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How to get fromMayo Clinic to Antiochby bus, car, plane, or train

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There are 8 ways to get from Mayo Clinic to Antioch by bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Rochester to Milwaukeebus bus Jefferson Lines 965
    2. Take the bus from Milwaukee Intermodal/Amtrak Station to Metro Train Station - 13th Avenue and 54th Streetbus bus Wisconsin Coach Lines
    8h 54m
    $128–178

  2. Fly Rochester to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Rochester (RST) to Chicago O'Hare International Airport (ORD)plane plane RST - ORD
    2. Take the train from O'Hare Transfer to Antiochtrain train
    5h 31m
    $42–349

  3. Drive 292.8 mi

    1. Drive from Mayo Clinic to Antiochcar car 292.8 mi
    5h 2m
    $54–78

  4. Bus, train

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Antiochtrain train Ncs
    11h 2m
    $102–164

  5. Bus, train via Madison

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Antiochtrain train Ncs
    11h 51m
    $86–142

  6. Bus, train via Madison #2

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from Madison to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Antiochtrain train Ncs
    12h 22m
    $86–132

  7. Bus to Minneapolis–Saint Paul International Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago O'Hare International Airport (ORD)plane plane MSP - ORD
    3. Take the train from O'Hare Transfer to Antiochtrain train
    6h 34m
    $276–562

  8. Bus to Minneapolis–Saint Paul International Airport, fly to Chicago Midway International Airport, train

    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Chicago Midway International Airport (MDW)plane plane MSP - MDW
    3. Take the train from Chicago Union Station to Antiochtrain train
    7h 20m
    $113–423

Mayo Clinic to Antioch by foot, bus, and train

Calendar7Weekly Services
Duration11h 2mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

Map of how to get from Mayo Clinic to Antioch.ExpandLaunch map view
  • Distance: 336.3 mi
  • Duration: 8h 54m

What companies run services between Mayo Clinic, MN, USA and Antioch, IL, USA?

You can take a vehicle from Mayo Clinic to Antioch via Rochester, Milwaukee, Milwaukee Intermodal/Amtrak Station, and Metro Train Station - 13th Avenue and 54th Street in around 8h 54m.

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Train operators
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