There are 6 ways to get from Mayo Clinic to Boston by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Rochester
best- Fly from Rochester (RST) to Boston Logan Airport (BOS)plane RST - BOS
6h 24m$181–887Bus
- Take the bus from Rochester, MN to Milwaukee, WI - Amtrakbus
- Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to New York Midtownbus
- Take the bus from New York Midtown to Bostonbus
32h 31m$258–413Bus, train via Madison
- Take the bus from Rochester, MN to UW-Madisonbus
- Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus
- Take the train from Chicago Union Station to Bostontrain
32h 43m$414–839Drive 1,326.8 mi
- Drive from Mayo Clinic to Bostoncar 1,326.8 mi
22h 31m$243–350Bus to Minneapolis–Saint Paul International Airport, fly
- Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus
- Fly from Minneapolis–Saint Paul International Airport (MSP) to Boston Logan Airport (BOS)plane MSP - BOS
5h 6m$390–1,000Bus, train
- Take the bus from Rochester to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bostontrain
32h 57m$489–1,009
Mayo Clinic to Boston by foot and bus
Questions & Answers
The cheapest way to get from Mayo Clinic to Boston is to drive which costs $240 - $350 and takes 22h 31m.
The fastest way to get from Mayo Clinic to Boston is to bus and fly which takes 5h 6m and costs $390 - $1,000.
No, there is no direct bus from Mayo Clinic to Boston. However, there are services departing from Rochester, MN and arriving at Boston via Milwaukee Intermodal Station, Chicago Bus Station and New York Midtown. The journey, including transfers, takes approximately 32h 31m.
The distance between Mayo Clinic and Boston is 1100 miles. The road distance is 1334.6 miles.
The best way to get from Mayo Clinic to Boston without a car is to bus which takes 32h 31m and costs $250 - $420.
It takes approximately 6h 24m to get from Mayo Clinic to Boston, including transfers.
Mayo Clinic to Boston bus services, operated by Jefferson Lines, depart from Rochester, MN station.
The best way to get from Mayo Clinic to Boston is to fly which takes 6h 24m and costs $180 - $900. Alternatively, you can bus, which costs $250 - $420 and takes 32h 31m.
Mayo Clinic to Boston bus services, operated by Jefferson Lines, arrive at Milwaukee, WI - Amtrak station.
Yes, the driving distance between Mayo Clinic to Boston is 1335 miles. It takes approximately 22h 31m to drive from Mayo Clinic to Boston.
What companies run services between Mayo Clinic, MN, USA and Boston, MA, USA?
United Airlines, American Airlines, and Delta fly from Rochester (RST) to Boston Logan Airport (BOS) every 4 hours. Alternatively, you can take a vehicle from Mayo Clinic to Boston via Rochester, MN, Milwaukee Intermodal Station, Chicago Bus Station, and New York Midtown in around 32h 31m.
- Website
- delta.com
Flights from Rochester to Boston Logan Airport via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 6h 50m
- When
- Every day
- Estimated price
- $190–900
Flights from Minneapolis–Saint Paul International Airport to Boston Logan Airport
- Ave. Duration
- 2h 51m
- When
- Every day
- Estimated price
- $110–550
Flights from Minneapolis–Saint Paul International Airport to Boston Logan Airport via Madison
- Ave. Duration
- 4h 37m
- When
- Sunday and Thursday
- Estimated price
- $110–550
Flights from Minneapolis–Saint Paul International Airport to Boston Logan Airport via Detroit
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $110–550
Flights from Minneapolis–Saint Paul International Airport to Boston Logan Airport via Milwaukee
- Ave. Duration
- 5h 4m
- When
- Saturday
- Estimated price
- $110–550
- Website
- aa.com
Flights from Rochester to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 7h 8m
- When
- Every day
- Estimated price
- $180–850
- Website
- suncountry.com
Flights from Minneapolis–Saint Paul International Airport to Boston Logan Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $110–550
- Website
- united.com
Flights from Rochester to Boston Logan Airport via Chicago O'Hare
- Ave. Duration
- 5h 1m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $330–700
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 32m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Boston
- Ave. Duration
- 22h 2m
- Frequency
- Once daily
- Estimated price
- $330–700
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Rochester, MN to Milwaukee, WI - Amtrak
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $70–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–110
Bus from Rochester, MN to UW-Madison
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $55–80
- Book at
- https://www.jeffersonlines.com
- Adult
- $55–80
Bus from Rochester to St. Paul
- Ave. Duration
- 1h 15m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Milwaukee Intermodal Station to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $14–23
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 17h 5m
- Frequency
- Twice daily
- Estimated price
- $140–230
- Schedules at
- flixbus.com
Bus from New York Midtown to Boston
- Ave. Duration
- 4h 20m
- Frequency
- Hourly
- Estimated price
- $30–55
- Schedules at
- flixbus.com
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton St
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $26–60
- Schedules at
- coachusa.com
- Adult
- $26–60
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airport
- Ave. Duration
- 1h
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
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